Patents by Inventor Christine Yang
Christine Yang has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 11752128Abstract: Novel compounds of the structural formula I, and the pharmaceutically acceptable salts thereof, are inhibitors of TarO and may be useful in the prevention, treatment and suppression of diseases mediated by TarO, such as bacterial infections, including gram negative bacterial infections and gram positive bacterial infections such as MRSA and MRSE, alone or in combination with a ?-lactam antibiotic.Type: GrantFiled: July 26, 2021Date of Patent: September 12, 2023Assignee: MERCK SHARP & DOHME CORPORATIONInventors: John P. Caldwell, Ginny Dai Ho, Sookhee N. Ha, Sandra J. Koseoglu, Marc A. Labroli, Sang Ho Lee, Christina Madsen-Duggan, Mihir Mandal, Jianping Pan, Weidong Pan, Terry Roemer, Jing Su, Christopher Michael Tan, Zheng Tan, Hao Wang, Christine Yang, Shu-Wei Yang
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Patent number: 11738010Abstract: Novel compounds of the structural formula I, and the pharmaceutically acceptable salts thereof, are inhibitors of TarO and may be useful in the prevention, treatment and suppression of diseases mediated by TarO, such as bacterial infections, including gram negative bacterial infections and gram positive bacterial infections such as MRSA and MRSE, alone or in combination with a ?-lactam antibiotic.Type: GrantFiled: July 26, 2021Date of Patent: August 29, 2023Assignee: MERCK SHARP & DOHME CORP.Inventors: John P. Caldwell, Reynalda De Jesus, Fa-Xiang Ding, Charles J. Gill, Ginny Dai Ho, Sookhee N. Ha, Sandra J. Koseoglu, Marc A. Labroli, Sang Ho Lee, Christina Madsen-Duggan, Mihir Mandal, Terry Roemer, Jing Su, Christopher Michael Tan, Zheng Tan, Haifeng Tang, Hao Wang, Christine Yang, Shu-Wei Yang
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Publication number: 20210346364Abstract: Novel compounds of the structural formula I, and the pharmaceutically acceptable salts thereof, are inhibitors of TarO and may be useful in the prevention, treatment and suppression of diseases mediated by TarO, such as bacterial infections, including gram negative bacterial infections and gram positive bacterial infections such as MRSA and MRSE, alone or in combination with a ?-lactam antibiotic.Type: ApplicationFiled: July 26, 2021Publication date: November 11, 2021Applicant: MERCK SHARP & DOHME CORP.Inventors: John P. CALDWELL, Reynalda DE JESUS, Fa-Xiang DING, Charles J. GIll, Ginny Dai HO, Sookhee N. HA, Sandra J. KOSEOGLU, Marc A. LABROLI, Sang Ho LEE, Christina MADSEN-DUGGAN, Mihir MANDAL, Terry ROEMER, Jing SU, Christopher Michael TAN, Zheng TAN, Haifeng TANG, Hao WANG, Christine YANG, Shu-Wei YANG
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Publication number: 20210346344Abstract: Novel compounds of the structural formula I, and the pharmaceutically acceptable salts thereof, are inhibitors of TarO and may be useful in the prevention, treatment and suppression of diseases mediated by TarO, such as bacterial infections, including gram negative bacterial infections and gram positive bacterial infections such as MRSA and MRSE, alone or in combination with a ?-lactam antibiotic.Type: ApplicationFiled: July 26, 2021Publication date: November 11, 2021Applicant: MERCK SHARP & DOHME CORP.Inventors: John P. CALDWELL, Ginny Dai HO, Sookhee N. HA, Sandra J. KOSEOGLU, Marc A. LABROLI, Sang Ho LEE, Christina MADSEN-DUGGAN, Mihir MANDAL, Jianping PAN, Weidong PAN, Terry ROEMER, Jing SU, Christopher Michael TAN, Zheng TAN, Hao WANG, Christine YANG, Shu-Wei YANG
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Patent number: 11141410Abstract: Novel compounds of the structural formula I, and the pharmaceutically acceptable salts thereof, are inhibitors of TarO and may be useful in the prevention, treatment and suppression of diseases mediated by TarO, such as bacterial infections, including gram negative bacterial infections and gram positive bacterial infections such as MRSA and MRSE, alone or in combination with a ?-lactam antibiotic.Type: GrantFiled: December 13, 2016Date of Patent: October 12, 2021Assignee: MERCK SHARP & DOHME CORPInventors: John P. Caldwell, Reynalda De Jesus, Fa-Xiang Ding, Charles J. Gill, Ginny Dai Ho, Sookhee N. Ha, Sandra J. Koseoglu, Marc A. Labroli, Sang Ho Lee, Christina Madsen-Duggan, Mihir Mandal, Terry Roemer, Jing Su, Christopher Michael Tan, Zheng Tan, Haifeng Tang, Hao Wang, Christine Yang, Shu-Wei Yang
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Patent number: 11141403Abstract: Novel compounds of the structural formula I, and the pharmaceutically acceptable salts thereof, are inhibitors of TarO and may be useful in the prevention, treatment and suppression of diseases mediated by TarO, such as bacterial infections, including gram negative bacterial infections and gram positive bacterial infections such as MRSA and MRSE, alone or in combination with a ?-lactam antibiotic.Type: GrantFiled: December 13, 2016Date of Patent: October 12, 2021Assignee: MERCK SHARP & DOHME CORPInventors: John P. Caldwell, Ginny Dai Ho, Sookhee N. Ha, Sandra J. Koseoglu, Marc A. Labroli, Sang Ho Lee, Christina Madsen-Duggan, Mihir Mandal, Jianping Pan, Weidong Pan, Terry Roemer, Jing Su, Christopher Michael Tan, Zheng Tan, Hao Wang, Christine Yang, Shu-Wei Yang
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Publication number: 20200261436Abstract: Novel compounds of the structural formula I, and the pharmaceutically acceptable salts thereof, are inhibitors of TarO and may be useful in the prevention, treatment and suppression of diseases mediated by TarO, such as bacterial infections, including gram negative bacterial infections and gram positive bacterial infections such as MRSA and MRSE, alone or in combination with a ?-lactam antibiotic.Type: ApplicationFiled: December 13, 2016Publication date: August 20, 2020Applicant: MERCK SHARP & DOHME CORP.Inventors: John P. CALDWELL, Reynalda DE JESUS, Fa-Xiang DING, Charles J. GIll, Ginny Dai HO, Sookhee N. HA, Sandra J. KOSEOGLU, Marc A. LABROLI, Sang Ho LEE, Christina MADSEN-DUGGAN, Mihir MANDAL, Terry ROEMER, Jing SU, Christopher Michael TAN, Zheng TAN, Haifeng TANG, Hao WANG, Christine YANG, Shu-Wei YANG
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Publication number: 20200261410Abstract: Novel compounds of the structural formula I, and the pharmaceutically acceptable salts thereof, are inhibitors of TarO and may be useful in the prevention, treatment and suppression of diseases mediated by TarO, such as bacterial infections, including gram negative bacterial infections and gram positive bacterial infections such as MRSA and MRSE, alone or in combination with a ?-lactam antibiotic.Type: ApplicationFiled: December 13, 2016Publication date: August 20, 2020Applicant: MERCK SHARP & DOHME CORP.Inventors: John P. CALDWELL, Ginny Dai HO, Sookhee N. HA, Sandra J. KOSEOGLU, Marc A. LABROLI, Sang Ho LEE, Christina MADSEN-DUGGAN, Mihir MANDAL, Jianping PAN, Weidong PAN, Terry ROEMER, Jin SU, Christopher Michael TAN, Zheng TAN, Hao WANG, Christine YANG, Shu-Wei YANG
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Patent number: 9505730Abstract: The present invention is directed to compounds of the Formula I as well as pharmaceutically acceptable salts thereof, that are potentially useful for treating aldosterone-mediated diseases. The invention furthermore relates to processes for preparing compounds of the Formula I, to their possible use in the treatment of the abovementioned diseases and for preparing pharmaceuticals for this purpose, and to pharmaceutical compositions which comprise compounds of the Formula I.Type: GrantFiled: October 8, 2012Date of Patent: November 29, 2016Assignee: Merck Sharp & Dohme Corp.Inventors: Hong Shen, Jason M. Cox, Christine Yang, Zhicai Wu
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Patent number: 9487506Abstract: Compounds of the Formula (I) as well as pharmaceutically acceptable salts thereof, that may be useful for treating aldosterone-mediated diseases are disclosed. Processes for preparing compounds of the Formula (I), use of the compounds for the therapy and prophylaxis of the abovementioned diseases and for preparing pharmaceuticals for this purpose, and pharmaceutical compositions which comprise compounds of the Formula (I) are disclosed.Type: GrantFiled: April 11, 2012Date of Patent: November 8, 2016Assignee: Merck Sharp & Dohme Corp.Inventors: Ping Lan, Kun Liu, Anthony Ogawa, Hong Shen, Christine Yang, Yuguang Wang, Richard Beresis, Changhe Qi
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Patent number: 9193717Abstract: The present invention is directed to compounds of the Formula (I) as well as pharmaceutically acceptable salts thereof, that are aldosterone receptor antagonists which might be useful for treating aldosterone-mediated diseases. The invention furthermore relates to processes for preparing compounds of the Formula (I), to their possible use for the treatment of the abovementioned diseases and for preparing pharmaceuticals for this purpose, and to pharmaceutical compositions which comprise compounds of the Formula (I).Type: GrantFiled: October 8, 2012Date of Patent: November 24, 2015Assignee: Merck Sharp & Dohme Corp.Inventors: Hong Shen, Christine Yang, Jason M. Cox, Kun Liu
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Publication number: 20150166490Abstract: The present invention is directed to compounds of the Formula I as well as pharmaceutically acceptable salts thereof, that are potentially useful for treating aldosterone-mediated diseases. The invention furthermore relates to processes for preparing compounds of the Formula I, to their possible use in the treatment of the abovementioned diseases and for preparing pharmaceuticals for this purpose, and to pharmaceutical compositions which comprise compounds of the Formula I.Type: ApplicationFiled: October 8, 2012Publication date: June 18, 2015Inventors: Hong Shen, Jason M. Cox, Christine Yang, Zhicai Wu
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Publication number: 20140336224Abstract: Compounds of the Formula (I) as well as pharmaceutically acceptable salts thereof, that may be useful for treating aldosterone-mediated diseases are disclosed. Processes for preparing compounds of the Formula (I), use of the compounds for the therapy and prophylaxis of the abovementioned diseases and for preparing pharmaceuticals for this purpose, and pharmaceutical compositions which comprise compounds of the Formula (I) are disclosed.Type: ApplicationFiled: October 18, 2012Publication date: November 13, 2014Inventors: Ping Lan, Kun Liu, Anthony Ogawa, Hong Shen, Christine Yang, Yuguang Wang, Richard Beresis, Changhe Qi
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Publication number: 20140256723Abstract: The present invention is directed to compounds of the Formula (I) as well as pharmaceutically acceptable salts thereof that are aldosterone receptor antagonists which might be useful for treating aldosterone-mediated diseases. The invention furthermore relates to processes for preparing compounds of the Formula (I), to their possible use for the treatment of the above-mentioned diseases and for preparing pharmaceuticals for this purpose, and to pharmaceutical compositions which comprise compounds of the Formula (I).Type: ApplicationFiled: October 8, 2012Publication date: September 11, 2014Inventors: Hong Shen, Christine Yang, Jason M. Cox, Kun Liu
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Publication number: 20080010585Abstract: A digital document and authoring tool for generating a digital document comprising a multi-channel interface is provided that achieves improved user interaction. The digital document includes a plurality of content channels providing primary content continuously in a looping manner and at least one supplementary channel on a single page. The supplementary channel is configured to provide supplementary content upon the occurrence of an event during playback of the document. Channel content may include video, text, images, 3D content, web page content, audio and any other suitable content. In addition to media content, a channel may contain interactive regions in the form of hot spots, and interactive mapping regions, and other interactive features. The codument can utilize a stage layout having at least one channel to present media and a collection of properties, the collection of properties forming a program.Type: ApplicationFiled: July 10, 2007Publication date: January 10, 2008Applicant: Fuji Xerox Co., Ltd.Inventors: Tina Schneider, Bee Liew, Christine Yang
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Publication number: 20050071736Abstract: A media collection and management tool for collecting, managing, and configuring media and media related properties. The tool configures media along with related media properties as a program, wherein a program is a collection of properties. Configurable media may include video, text, images, 3D content, web page content and audio. In addition to media content, a program may be configured to include interactive regions in the form of hot spots, interactive mapping regions, and other interactive features. The media collection and management tool utilizes intuitive interfaces to configure programs. The media and programs can be exported to other media components, such as a digital document authoring tool.Type: ApplicationFiled: September 26, 2003Publication date: March 31, 2005Applicant: Fuji Xerox Co., Ltd.Inventors: Tina Schneider, Bee Liew, Christine Yang, Jonathan Helfman
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Publication number: 20050069225Abstract: A digital document and authoring tool for generating a digital document comprising a multi-channel interface is provided that achieves improved user interaction. The digital document includes a plurality of content channels providing primary content continuously in a looping manner and at least one supplementary channel on a single page. The supplementary channel is configured to provide supplementary content upon the occurrence of an event during playback of the document. Channel content may include video, text, images, 3D content, web page content, audio and any other suitable content. In addition to media content, a channel may contain interactive regions in the form of hot spots, and interactive mapping regions, and other interactive features. The codument can utilize a stage layout having at least one channel to present media and a collection of properties, the collection of properties forming a program.Type: ApplicationFiled: September 26, 2003Publication date: March 31, 2005Applicant: Fuji Xerox Co., Ltd.Inventors: Tina Schneider, Bee Liew, Christine Yang