Patents by Inventor Christof Brehm

Christof Brehm has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Preparing silicone emulsions
    Patent number: 8575266
    Abstract: The invention provides a process for preparing emulsions of organopolysiloxanes (O), which includes polymerizing: (1) 100 parts by weight of hydroxyl-terminated organopolysiloxanes and (2) at least 0.01 part by weight of trialkylsilyl-terminated organopolysiloxanes having a viscosity of at least 55 mm2/s in the presence of (3) acidic catalyst and (4) emulsifier in an aqueous medium until the desired molecular size is reached.
    Type: Grant
    Filed: May 2, 2011
    Date of Patent: November 5, 2013
    Assignee: Wacker Chemie AG
    Inventors: Christof Brehm, Robert Schroeck
  • FULLY ACYLATED AMINO-FUNCTIONAL ORGANOPOLYSILOXANES
    Publication number: 20130280201
    Abstract: Fully acylated hydroxyl-terminated organopolysiloxanes bearing pendant aminoalkyl groups are easily prepared by reacting a hydroxyl-terminated, aminoalkyl organopolysiloxane with a carboxylic anhydride in stoichiometric amount relative to amino groups, in the presence of at least one emulsifier.
    Type: Application
    Filed: September 19, 2011
    Publication date: October 24, 2013
    Applicant: WACKER CHEMIE AG
    Inventors: Christof Brehm, Gerhard Beer, Markus Merget
  • PREPARING SILICONE EMULSIONS
    Publication number: 20110269892
    Abstract: The invention provides a process for preparing emulsions of organopolysiloxanes (O), which includes polymerizing: (1) 100 parts by weight of hydroxyl-terminated organopolysiloxanes and (2) at least 0.01 part by weight of trialkylsilyl-terminated organopolysiloxanes having a viscosity of at least 55 mm2/s in the presence of (3) acidic catalyst and (4) emulsifier in an aqueous medium until the desired molecular size is reached.
    Type: Application
    Filed: May 2, 2011
    Publication date: November 3, 2011
    Applicant: WACKER CHEMIE AG
    Inventors: Christof BREHM, Robert SCHROECK
  • Spiro-benzimidazoles as inhibitors of gastric acid secretion
    Publication number: 20090093473
    Abstract: The invention provides compounds of the formula (I) In which the substituents and symbols are as defined in the description. The compounds inhibit the secretion of gastric acid.
    Type: Application
    Filed: June 13, 2006
    Publication date: April 9, 2009
    Inventors: Peter Jan Zimmermann, Jorg Senn-Bilfinger, Christof Brehm, Wilm Buhr, Maria Vittoria Chiesa, Andreas Palmer, Wolfgang-Alexander Simon, Stefan Postius, Wolfgang Kromer
  • Process For the Production of Intermediates For the Preparation of Tricyclic Benzimidazoles
    Publication number: 20080280855
    Abstract: The invention relates to a process for the synthesis of compounds of the formula 1-a and compounds of the formula 1-b. The compounds of the formula 1-a and the compounds of the formula 1-b, in which the substituents R1, R2, R3, and Ar have the meanings indicated in the description, are valuable intermediates for the preparation of pharmaceutically active compounds.
    Type: Application
    Filed: June 20, 2006
    Publication date: November 13, 2008
    Applicant: NYCOMED GmbH
    Inventors: Maria Vittoria Chiesa, Andreas Palmer, Wilm Buhr, Peter Jan Zimmermann, Christof Brehm, Wolfgang-Alexander Simon, Stefan Postius, Wolfgang Kromer, Antonio Zanotti-Gerosa
  • Substituted Imidazo [4,5-B] Pyridines As Inhibitors Of Gastric Acid Secretion
    Publication number: 20080119510
    Abstract: The invention provides compounds of the formula (I) in which the substituents and symbols are as defined in the description. The compounds inhibit the secretion of gastric acid.
    Type: Application
    Filed: December 6, 2005
    Publication date: May 22, 2008
    Applicant: Altana Pharma AG
    Inventors: Christof Brehm, Wilm Buhr, M. Vittoria Chiesa, Andreas Palmer, Peter Jan Zimmermann, Wolfgang-Alexander Simon, Stefan Postius, Wolfgang Kromer
  • Difluoro-Substituted Imidazopyridines
    Publication number: 20080114020
    Abstract: The invention provides compounds of the formula (I) in which the substituents and symbols are as defined in the description. The compounds inhibit the secretion of gastric acid.
    Type: Application
    Filed: October 13, 2005
    Publication date: May 15, 2008
    Applicant: Altana Pharma AG
    Inventors: Wilm Buhr, Peter Jan Zimmermann, Christof Brehm, Adreas Palmer, M.Vittoria Chiesa, Wolfgang-Alexander Simon, Stefan Postius, Wolfgang Kromer, Georg Rast, Udo Doelling
  • Condensed Tricyclic Benzimidazoles For the Treatment of Gastrointestinal Disorders
    Publication number: 20080113962
    Abstract: The invention relates to condensed tricyclic benzimidazoles of formula (I) in which the substituents and symbols have the meanings indicated in the description. The compounds have gastric secretion inhibiting and excellent gastric and intestinal protective action properties.
    Type: Application
    Filed: September 30, 2005
    Publication date: May 15, 2008
    Applicant: Aitana Pharma AG
    Inventors: Peter Jan Zimmermann, Wilm Buhr, Christof Brehm, Andreas Palmer, M. Vittoria Chiesa, Wolfgang-Alexander Simon, Stefan Postius, Wolfgang Kromer
  • Substituted Tricyclic Benzimidazoles
    Publication number: 20070244154
    Abstract: The invention relates to compounds of the formula (1) in which the substituents and symbols have the meanings indicated in the description. The compounds have gastric secretion inhibiting and excellent gastric and intestinal protective action properties.
    Type: Application
    Filed: June 7, 2005
    Publication date: October 18, 2007
    Applicant: Altana Pharma AG
    Inventor: Christof Brehm
  • Imidazopyridine intermediates
    Patent number: 7256293
    Abstract: The invention relates to compounds of the formula 1, in which the substituents and symbols have the meanings indicated in the description. The compounds are valuable intermediates for the preparation of pharmaceutical active compounds.
    Type: Grant
    Filed: May 4, 2004
    Date of Patent: August 14, 2007
    Assignee: Altana Pharma AG
    Inventors: Christof Brehm, Wilm Buhr
  • Imidazopyridine intermediates
    Publication number: 20060276499
    Abstract: The invention relates to compounds of the formula (I), in which the substituents and symbols have the meanings indicated in the description. The compounds are valuable intermediates for the preparation of pharmaceutical active compounds.
    Type: Application
    Filed: May 4, 2004
    Publication date: December 7, 2006
    Applicant: Altana Pharma AG
    Inventors: Christof Brehm, Wilm Buhr
  • Combinations and use of selected pharmaceutically active compounds
    Publication number: 20060154954
    Abstract: The present invention relates to new combinations and new uses of certain selected tricyclic imidazo [1,2-a]pyridine compounds in the prevention or treatment of medicament caused gastrointestinal diseases.
    Type: Application
    Filed: February 16, 2004
    Publication date: July 13, 2006
    Applicant: ALTANA PHARMA AG
    Inventors: Wilm Buhr, Wolfgang Kromer, Peter Zimmermann, Andreas Palmer, Christof Brehm, Thomas Klein, Joerg Senn-Bilfinger, Wolfgang-Alexander Simon, Stefan Postius
  • 6-Substituted imidazopyrazines
    Publication number: 20060148796
    Abstract: The present invention relates to 6-substituted imidazopyrazines of formula 1 in which the substituents and symbols have the meanings indicated in the description. The compounds have gastric secretion inhibiting and excellent gastric and intestinal protective action properties.
    Type: Application
    Filed: February 16, 2004
    Publication date: July 6, 2006
    Inventors: Peter Zimmermann, Wilm Buhr, M. Chiesa, Andreas Palmer, Christof Brehm, Gerhard Grundler, Joerg Senn-Bilfinger, Wolfgang-Alexander Simon, Stefan Postius, Wolfgang Kromer