Patents by Inventor Christof M. Kramm

Christof M. Kramm has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Folypolyglutamyl synthetase gene transfer to enhance antifolate
    Patent number: 6770632
    Abstract: Methods of killing neoplastic cells are provided. The invention relates to the use of folylpolyglutamyl synthetase (FPGS) gene transfer to enhance the sensitivity of several types of tumor cells to polyglutamylatable antifolate drugs, such as methotrexate (MTX) and edatrexate (EDX).
    Type: Grant
    Filed: July 14, 2000
    Date of Patent: August 3, 2004
    Assignee: The General Hospital Corporation
    Inventors: Manish Aghi, Christof M. Kramm, Xandra O. Breakefield