Patents by Inventor Christof Spitzley

Christof Spitzley has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Pharmaceutical preparation containing oxycodone and naloxone
    Patent number: 10420762
    Abstract: The invention concerns a storage stable pharmaceutical preparation comprising oxycodone and naloxone for use in pain therapy, with the active compounds being released from the preparation in a sustained, invariant and independent manner.
    Type: Grant
    Filed: January 26, 2018
    Date of Patent: September 24, 2019
    Assignee: Purdue Pharma L.P.
    Inventors: Bianca Brögmann, Silke Mühlau, Christof Spitzley
  • PHARMACEUTICAL PREPARATION CONTAINING OXYCODONE AND NALOXONE
    Publication number: 20180214443
    Abstract: The invention concerns a storage stable pharmaceutical preparation comprising oxycodone and naloxone for use in pain therapy, with the active compounds being released from the preparation in a sustained, invariant and independent manner.
    Type: Application
    Filed: January 26, 2018
    Publication date: August 2, 2018
    Inventors: Bianca BRÖGMANN, Silke MÜHLAU, Christof SPITZLEY
  • ALCOHOL RESISTANT DOSAGE FORMS
    Publication number: 20180153812
    Abstract: Opioid controlled release formulation resistant to alcohol extraction of the opioid.
    Type: Application
    Filed: February 1, 2018
    Publication date: June 7, 2018
    Inventors: Richard O. Mannion, William H. Mckenna, Edward P. O'donnell, Helen Kathleen Danagher, Geoffrey Gerard Hayes, Hassan Mohammad, Derek Allan Prater, Harjit Tamber, Malcolm Walden, Steve Whitelock, Wolfgang Fleischer, Udo Hahn, Christof Spitzley, Christian Leuner
  • Pharmaceutical preparation containing oxycodone and naloxone
    Patent number: 9907793
    Abstract: The invention concerns a storage stable pharmaceutical preparation comprising oxycodone and naloxone for use in pain therapy, with the active compounds being released from the preparation in a sustained, invariant and independent manner.
    Type: Grant
    Filed: January 5, 2017
    Date of Patent: March 6, 2018
    Assignee: Purdue Pharma L.P.
    Inventors: Bianca Brögmann, Silke Mühlau, Christof Spitzley
  • MATRIX FOR SUSTAINED, INVARIANT AND INDEPENDENT RELEASE OF ACTIVE COMPOUNDS
    Publication number: 20170231978
    Abstract: The invention concerns a storage stable pharmaceutical formulation comprising preferably two active compounds in a non-swellable diffusion matrix, whereby the compounds are released from the matrix in a sustained, invariant and, if several compounds are present, independent manner and the matrix is determined with respect to its substantial release characteristics by ethylcellulose and at least one fatty alcohol. The invention also concerns methods for producing such pharmaceutical formulations.
    Type: Application
    Filed: April 28, 2017
    Publication date: August 17, 2017
    Inventors: Bianca BRÖGMANN, Silke MÜHLAU, Christof SPITZLEY
  • Matrix for sustained, invariant and independent release of active compounds
    Patent number: 9655855
    Abstract: The invention concerns a storage stable pharmaceutical formulation comprising preferably two active compounds in a non-swellable diffusion matrix, whereby the compounds are released from the matrix in a sustained, invariant and, if several compounds are present, independent manner and the matrix is determined with respect to its substantial release characteristics by ethylcellulose and at least one fatty alcohol. The invention also concerns methods for producing such pharmaceutical formulations.
    Type: Grant
    Filed: September 17, 2014
    Date of Patent: May 23, 2017
    Assignee: Purdue Pharma L.P.
    Inventors: Bianca Brögmann, Silke Mühlau, Christof Spitzley
  • PHARMACEUTICAL PREPARATION CONTAINING OXYCODONE AND NALOXONE
    Publication number: 20170112828
    Abstract: The invention concerns a storage stable pharmaceutical preparation comprising oxycodone and naloxone for use in pain therapy, with the active compounds being released from the preparation in a sustained, invariant and independent manner.
    Type: Application
    Filed: January 5, 2017
    Publication date: April 27, 2017
    Inventors: Bianca BRÖGMANN, Silke MÜHLAU, Christof SPITZLEY
  • ALCOHOL RESISTANT DOSAGE FORMS
    Publication number: 20170079923
    Abstract: Opioid controlled release formulation resistant to alcohol extraction of the opioid.
    Type: Application
    Filed: December 1, 2016
    Publication date: March 23, 2017
    Inventors: Richard O. MANNION, William H. MCKENNA, Edward P. O'DONNELL, Helen Kathleen DANAGHER, Geoffrey Gerard HAYES, Hassan MOHAMMAD, Derek Allan PRATER, Harjit TAMBER, Malcolm WALDEN, Steve WHITELOCK, Wolfgang FLEISCHER, Udo HAHN, Christof SPITZLEY, Christian LEUNER
  • Pharmaceutical preparation containing oxycodone and naloxone
    Patent number: 9555000
    Abstract: The invention concerns a storage stable pharmaceutical preparation comprising oxycodone and naloxone for use in pain therapy, with the active compounds being released from the preparation in a sustained, invariant and independent manner.
    Type: Grant
    Filed: June 16, 2014
    Date of Patent: January 31, 2017
    Assignee: Purdue Pharma L.P.
    Inventors: Bianca Brögmann, Silke Mühlau, Christof Spitzley
  • USE OF BINDERS FOR MANUFACTURING STORAGE STABLE FORMULATIONS
    Publication number: 20160095853
    Abstract: The present invention relates to storage stable prolonged release pharmaceutical dosage forms comprising oxycodone or a pharmaceutically acceptable salt thereof and naloxone or a pharmaceutically acceptable salt thereof, the manufacture thereof as well as their use for administration to human beings.
    Type: Application
    Filed: December 14, 2015
    Publication date: April 7, 2016
    Inventors: Derek Allan PRATER, Christof SPITZLEY, Gerhard Josef HEUN, Alexander SCHÜTZ, Udo HAHN, Christian LEUNER
  • MATRIX FOR SUSTAINED, INVARIANT AND INDEPENDENT RELEASE OF ACTIVE COMPOUNDS
    Publication number: 20150005335
    Abstract: The invention concerns a storage stable pharmaceutical formulation comprising preferably two active compounds in a non-swellable diffusion matrix, whereby the compounds are released from the matrix in a sustained, invariant and, if several compounds are present, independent manner and the matrix is determined with respect to its substantial release characteristics by ethylcellulose and at least one fatty alcohol. The invention also concerns methods for producing such pharmaceutical formulations.
    Type: Application
    Filed: September 17, 2014
    Publication date: January 1, 2015
    Inventors: Bianca BRÖGMANN, Silke MÜHLAH, Christof Spitzley
  • PHARMACEUTICAL PREPARATION CONTAINING OXYCODONE AND NALOXONE
    Publication number: 20140296277
    Abstract: The invention concerns a storage stable pharmaceutical preparation comprising oxycodone and naloxone for use in pain therapy, with the active compounds being released from the preparation in a sustained, invariant and independent manner.
    Type: Application
    Filed: June 16, 2014
    Publication date: October 2, 2014
    Inventors: Bianca Brögmann, Silke Mühlau, Christof Spitzley
  • Matrix for sustained, invariant and independent release of active compounds
    Patent number: 8846091
    Abstract: The invention concerns a storage stable pharmaceutical formulation comprising preferably two active compounds in a non-swellable diffusion matrix, whereby the compounds are released from the matrix in a sustained, invariant and, if several compounds are present, independent manner and the matrix is determined with respect to its substantial release characteristics by ethylcellulose and at least one fatty alcohol. The invention also concerns methods for producing such pharmaceutical formulations.
    Type: Grant
    Filed: October 18, 2013
    Date of Patent: September 30, 2014
    Assignee: Euro-Celtique S.A.
    Inventors: Bianca Brögmann, Silke Mühlah, Christof Spitzley
  • Matrix for sustained, invariant and independent release of active compounds
    Patent number: 8846090
    Abstract: The invention concerns a storage stable pharmaceutical formulation comprising preferably two active compounds in a non-swellable diffusion matrix, whereby the compounds are released from the matrix in a sustained, invariant and, if several compounds are present, independent manner and the matrix is determined with respect to its substantial release characteristics by ethylcellulose and at least one fatty alcohol. The invention also concerns methods for producing such pharmaceutical formulations.
    Type: Grant
    Filed: January 11, 2012
    Date of Patent: September 30, 2014
    Assignee: Euro-Celtique S.A.
    Inventors: Bianca Brögmann, Silke Muhlau, Christof Spitzley
  • MATRIX FOR SUSTAINED, INVARIANT AND INDEPENDENT RELEASE OF ACTIVE COMPOUNDS
    Publication number: 20140045878
    Abstract: The invention concerns a storage stable pharmaceutical formulation comprising preferably two active compounds in a non-swellable diffusion matrix, whereby the compounds are released from the matrix in a sustained, invariant and, if several compounds are present, independent manner and the matrix is determined with respect to its substantial release characteristics by ethylcellulose and at least one fatty alcohol. The invention also concerns methods for producing such pharmaceutical formulations.
    Type: Application
    Filed: October 18, 2013
    Publication date: February 13, 2014
    Applicant: Euro-Celtique S.A.
    Inventors: Bianca BRÖGMANN, Silke MÜHLAH, Christof SPITZLEY
  • PHARMACEUTICAL PREPARATION CONTAINING OXYCODONE AND NALOXONE
    Publication number: 20140045877
    Abstract: The invention concerns a storage stable pharmaceutical preparation comprising oxycodone and naloxone for use in pain therapy, with the active compounds being released from the preparation in a sustained, invariant and independent manner.
    Type: Application
    Filed: October 18, 2013
    Publication date: February 13, 2014
    Applicant: Purdue Pharma L.P.
    Inventors: Bianca BRÖGMANN, Silke MÜHLAH, Christof SPITZLEY
  • USE OF BINDERS FOR MANUFACTURING STORAGE STABLE FORMULATIONS
    Publication number: 20130245054
    Abstract: The present invention relates to storage stable prolonged release pharmaceutical dosage forms comprising oxycodone or a pharmaceutically acceptable salt thereof and naloxone or a pharmaceutically acceptable salt thereof, the manufacture thereof as well as their use for administration to human beings.
    Type: Application
    Filed: August 11, 2011
    Publication date: September 19, 2013
    Inventors: Derek Allan Prater, Christof Spitzley, Gerhard Heun, Alexander Schütz, Udo Hahn, Christian Leuner
  • MATRIX FOR SUSTAINED, INVARIANT AND INDEPENDENT RELEASE OF ACTIVE COMPOUNDS
    Publication number: 20120183612
    Abstract: The invention concerns a storage stable pharmaceutical formulation comprising preferably two active compounds in a non-swellable diffusion matrix, whereby the compounds are released from the matrix in a sustained, invariant and, if several compounds are present, independent manner and the matrix is determined with respect to its substantial release characteristics by ethylcellulose and at least one fatty alcohol. The invention also concerns methods for producing such pharmaceutical formulations.
    Type: Application
    Filed: January 11, 2012
    Publication date: July 19, 2012
    Applicant: Euro-Celtique S.A.
    Inventors: Bianca BRÖGMANN, Silke Mühlau, Christof Spitzley
  • ALCOHOL RESISTANT DOSAGE FORMS
    Publication number: 20120141583
    Abstract: Opioid controlled release formulation resistant to alcohol extraction of the opioid.
    Type: Application
    Filed: June 9, 2011
    Publication date: June 7, 2012
    Applicant: Euro-Celtique S.A.
    Inventors: Richard O. Mannion, William H. Mckenna, Edward P. O'Donnell, Helen Kathleen Danagher, Geoffrey Gerard Hayes, Hassan Mohammad, Derek Allan Prater, Harjit Tamber, Malcom Walden, Steve Whitelock, Wolfgang Fleischer, Udo Hahn, Christof Spitzley, Christian Leuner
  • PHARMACEUTICAL PREPARATION CONTAINING OXYCODONE AND NALOXONE
    Publication number: 20120108621
    Abstract: The invention concerns a storage stable pharmaceutical preparation comprising oxycodone and naloxone for use in pain therapy, with the active compounds being released from the preparation in a sustained, invariant and independent manner.
    Type: Application
    Filed: September 30, 2011
    Publication date: May 3, 2012
    Applicant: Purdue Pharma L.P.
    Inventors: Bianca BRÖGMANN, Silke Mühlau, Christof Spitzley