Patents by Inventor Christoph Brandenbusch

Christoph Brandenbusch has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 10343130
    Abstract: A method processes a stable emulsion having components from whole-cell biotransformations such as cells, soluble cell components, organic solvents and/or water. In this connection, the emulsion, which is stable after the biotransformation, is mixed with further parts of organic phase, and subsequently the mixture is continuously stirred until a catastrophic phase inversion of the emulsion takes place while mixing; subsequently, this phase-inverted mixture is transferred to a settling container, where the phases of the emulsion separate from one another and can be separated from one another.
    Type: Grant
    Filed: November 5, 2014
    Date of Patent: July 9, 2019
    Assignee: Technische Universitaet Dortmund
    Inventors: Christoph Brandenbusch, Gabriele Sadowski, Bruno Buehler, Jonathan A. Collins
  • Publication number: 20150125931
    Abstract: A method processes a stable emulsion having components from whole-cell biotransformations such as cells, soluble cell components, organic solvents and/or water. In this connection, the emulsion, which is stable after the biotransformation, is mixed with further parts of organic phase, and subsequently the mixture is continuously stirred until a catastrophic phase inversion of the emulsion takes place while mixing; subsequently, this phase-inverted mixture is transferred to a settling container, where the phases of the emulsion separate from one another and can be separated from one another.
    Type: Application
    Filed: November 5, 2014
    Publication date: May 7, 2015
    Applicant: TECHNISCHE UNIVERSITAET DORTMUND
    Inventors: Christoph BRANDENBUSCH, Gabriele SADOWSKI, Bruno BUEHLER, Jonathan A. COLLINS
  • Patent number: 8431358
    Abstract: The method separates emulsions derived from whole-cell biotransformations, including stable emulsions derived from typical biocatalytic two-phase processes that result with such a biotransformation. A supercritical extraction to obtain the valuable product can follow directly, because of the use of compressed or supercritical gas as the separation agent. It is unimportant whether the valuable product is present in the aqueous or the organic phase. Recycling of the organic phase is possible, since the surfactant cell components decisively responsible for the formation of the stable emulsion can be separated off via sedimentation, because of the treatment. The achieved separation remains in existence even after the gas has gassed out, so that aside from extraction, other methods for product isolation can also follow, if necessary.
    Type: Grant
    Filed: July 20, 2008
    Date of Patent: April 30, 2013
    Assignee: Technische Universitaet Dortmund
    Inventors: Gabriele Sadowski, Andreas Schmid, Bruno Buehler, Michael Goernert, Christoph Brandenbusch
  • Publication number: 20100145082
    Abstract: The method presented represents a possibility for separating emulsions derived from whole-cell biotransformations, which method makes it possible to effectively separate stable emulsions derived from typical biocatalytic two-phase processes that result in connection with such a biotransformation, by means of at least one compressed or supercritical gas. In this connection, a supercritical extraction to obtain the valuable product can follow directly, because of the use of compressed or supercritical gas as the separation agent. It is unimportant, in this connection, whether the valuable product is present in the aqueous or the organic phase. Recycling of the organic phase is possible, since the surfactant cell components, which are decisively responsible for the formation of the stable emulsion, can be separated off by means of sedimentation, because of the treatment.
    Type: Application
    Filed: July 20, 2008
    Publication date: June 10, 2010
    Inventors: Gabriele Sadowski, Andreas Schmid, Bruno Buehler, Michael Goernert, Christoph Brandenbusch