Abstract: A topically applicable preparation, particularly a cosmetic or dermatological preparation, comprising a substance combination of water, hyaluronic acid and/or hyaluronate salt, one or more fruit acids, one or more skin moisturizers and one or more alcohols can be successfully used for skin care, especially for preventing and treating the damage caused by atopic dermatitis of the skin and caring for such skin, without containing lipids and emollients that are typically included.

Abstract: Disclosed is a “Powder Bed Fusion” technique by sintering or melting through a sinter/melting device executed by a simulation model assigned to a control unit and under a control sovereignty of the control unit powder material, being fillable into a powder material bed, to tilt according to the simulation model and under the control sovereignty of the control unit a build platform of the powder material bed, in which the sintered or melted powder material an additive manufactured object is built up layer by layer on the build platform in a cavity of an additive manufacturing machine and wherein the build platform is both, moveable downwards or upwards and tiltable clockwise or counter-clockwise,: within the cavity during the layer by layer build-up an overhang angle as a maximum allowable additive manufacturing angle either referring to an additive manufacturing level is not undershot or an additive manufacturing direction is not exceeded.

Abstract: Various examples are directed to systems and methods of using a database management system (DBMS) to post a transaction. An enterprise resource planning (ERP) application may receive first transaction data associated with a first transaction including acquisition of a first component of a first component type. The first transaction data may describe an indicator of the first component, a cost of the first component of a first component type, and a first environmental metric associated with the first component. The ERP application may write a first transaction entry to a universal journal table of the DBMS, the first transaction entry comprising a description of the first transaction, and a component breakdown key. The ERP application may also write a first component breakdown entry to a component breakdown table of the DBMS.

Abstract: Compounds, pharmaceutical compositions, and methods of use of said compounds and pharmaceutical compositions for treating or preventing a microbial infection or for inducing antimicrobial activity against a microbial infection.

Abstract: The present invention relates to novel compounds that inhibit Lp-PLA2 activity, processes for their preparation, to compositions containing them and to their use in the treatment of diseases associated with the activity of Lp-PLA2, for example Alzheimer's disease.

Abstract: A computer-implemented method of monitoring and/or controlling an electro-mechanical device, such as an electrical motor and/or generator, includes determining a first probability distribution of a virtual measurement variable, such as temperature at a predetermined position, of the electro-mechanical device. A confidence level is determined for a first value of the virtual measurement variable based on the first probability distribution. An operating mode of the electro-mechanical device is changed based on the confidence level, and/or an indication is displayed on a display. The indication instructs a user to change the operating mode of the electro-mechanical device.

Abstract: For detecting a cyber-attack on a machine controller, a concurrent simulation of the machine is run in a secured access domain. From the machine controller actual control data are transmitted to the machine and resulting monitoring data are transmitted to a monitoring device. Furthermore, sensor data of the machine are transmitted to the concurrent simulation on a first secured transmission path. Based on the sensor data, the concurrent simulation simulates an operational behavior of the machine, thus inferring simulated monitoring data. The simulated monitoring data are then compared with the resulting monitoring, and an alarm signal is triggered depending on the comparison.

Abstract: In order to repair a workpiece, a requirement specification about a requirement to be met by the workpiece and a numerical simulation model for simulating a physical behavior of the workpiece are imported. Furthermore, a current shape of the workpiece is detected by means of a sensor. Where a deviation of the current shape from a target shape S of the workpiece is identified, a respective physical behavior of the workpiece in its current shape and in a shape added to by means of a 3D printer are simulated using the simulation model. Furthermore, a check is performed on the basis of the requirement specification to ascertain whether the simulated physical behavior meets the requirement. Depending on the outcome of the check, the workpiece is then either left in its current shape, added to by the 3D printer or discarded.

Abstract: Cosmetic preparation containing a) 4-(tert.-butyl)-4?-methoxydibenzoyl methane and/or (2-[-4-(diethylamino)-2-hydroxybenzoyl] benzoic acid hexyl ester (INCI: Diethylamino Hydroxybenzoyl Hexyl Benzoate) and b) diisostearoyl polyglyceryl-3-dimer-dilinoleate.

Abstract: Allergenic substances, allergens, are captured by topically applicable preparations comprising peptides that consist of 2-10 amino acids, at least one amino acid having one or more reactive side chains. The preparation comprises antioxidants and/or the pH of the preparation is less than 7. This barrier effect of the preparation allows for a novel anti-allergic form of therapy.

Abstract: Allergenic substances, allergens, are intercepted by peptides that consist of 2-10 amino acids, at least one amino acid having one or more reactive side chains. This barrier effect of the peptides, in particular in topically administrable preparations, allows for a new antiallergic form of therapy.

Abstract: A computer-implemented method is provided for predicting a fatigue response of a material. The method includes receiving a user input specifying one or more surface roughness parameters that characterize a surface of a material for which fatigue life is to be predicted. The method further includes generating at least one realistic virtual surface profile from the specified one or more surface roughness parameters. The method further includes predicting fatigue life of the material in dependence of a stress field applied to the generated virtual surface profile. In accordance with specific embodiments, the prediction of the fatigue life may be carried out using finite element analysis based simulations, machine learning methods, or combinations thereof.

Abstract: Described herein are pretreatment compositions, coated aluminum alloy products, and methods for coating the alloys. The pretreatment compositions include inorganic chemical corrosion inhibitors dispersed in a silane-based matrix and may further include clay particles. The inorganic chemical corrosion inhibitors include rare earth metals and salts thereof. The pretreatment compositions, when applied to the surface of an alloy, inhibit corrosion of the alloys. The pretreatment compositions can be used in automotive, electronics, industrial, transportation, and other applications.

Abstract: The present invention relates to novel compounds that inhibit Lp-PLA2 activity, processes for their preparation, to compositions containing them and to their use in the treatment of diseases associated with the activity of Lp-PLA2, for example Alzheimer's disease.

Abstract: A microwave branching switch for selectively interconnecting terminals of a plurality of microwave transmission lines, involving microwave transmission lines with a terminal; a housing in which the terminals are arranged; a switching portion with a junction portion for selectively interconnecting terminals of the microwave transmission lines through selective interconnection. The switching portion is switchable between a first position and a second position; wherein the switching portion with the junction portion is dimensioned and positioned inside the housing in dependence of an arrangement of the microwave transmission lines such that the junction portion interconnects a first group of terminals when the switching portion is in the first position and interconnects a second group of terminals when the switching portion is in the second position. The first and second groups of terminals differ in at least one terminal and the first group of terminals involves at least three terminals.

Abstract: The present invention relates to novel compounds that inhibit Lp-PLA2 activity, processes for their preparation, to compositions containing them and to their use in the treatment of diseases associated with the activity of Lp-PLA2, for example Alzheimer's disease.

Abstract: Described herein are pretreatment compositions, coated aluminum alloy products, and methods for coating the alloys. The pretreatment compositions include inorganic chemical corrosion inhibitors dispersed in a silane-based matrix and may further include clay particles. The inorganic chemical corrosion inhibitors include rare earth metals and salts thereof. The pretreatment compositions, when applied to the surface of an alloy, inhibit corrosion of the alloys. The pretreatment compositions can be used in automotive, electronics, industrial, transportation, and other applications.

Abstract: The present invention relates to novel compounds that inhibit Lp-PLA2 activity, processes for their preparation, to compositions containing them and to their use in the treatment of diseases associated with the activity of Lp-PLA2, for example Alzheimer's disease.

Abstract: The present invention relates to novel compounds that inhibit Lp-PLA2 activity, processes for their preparation, to compositions containing them and to their use in the treatment of diseases associated with the activity of Lp-PLA2, for example Alzheimer's disease.

Abstract: A microwave branching switch for selectively interconnecting terminals of a plurality of microwave transmission lines, involving microwave transmission lines with a terminal; a housing in which the terminals are arranged; a switching portion with a junction portion for selectively interconnecting terminals of the microwave transmission lines through selective interconnection. The switching portion is switchable between a first position and a second position; wherein the switching portion with the junction portion is dimensioned and positioned inside the housing in dependence of an arrangement of the microwave transmission lines such that the junction portion interconnects a first group of terminals when the switching portion is in the first position and interconnects a second group of terminals when the switching portion is in the second position. The first and second groups of terminals differ in at least one terminal and the first group of terminals involves at least three terminals.