Patents by Inventor Christoph Freiberg

Christoph Freiberg has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • NEUTRALIZING PROLACTIN RECEPTOR ANTIBODIES AND THEIR THERAPEUTIC USE
    Publication number: 20130022606
    Abstract: The present invention is directed to the neutralizing prolactin receptor antibody 006-H07, and antigen binding fragments, pharmaceutical compositions containing them and their use in the treatment or prevention of benign disorders and indications mediated by the prolactin receptor such as endometriosis, adenomyosis, non-hormonal female contraception, benign breast disease and mastalgia, lactation inhibition, benign prostate hyperplasia, fibroids, hyper- and normoprolactinemic hair loss, and cotreatment in combined hormone therapy to inhibit mammary epithelial cell proliferation. The antibodies of the invention block prolactin receptor-mediated signaling.
    Type: Application
    Filed: November 18, 2010
    Publication date: January 24, 2013
    Applicant: BAYER INTELLECTUAL PROPERTY GMBH
    Inventors: Christiane Otto, Siegmund Wolf, Christoph Freiberg, Axel Harrenga, Simone Greven, Mark Trautwein, Sandra Bruder
  • NEUTRALIZING PROLACTIN RECEPTOR ANTIBODIES AND THEIR THERAPEUTIC USE
    Publication number: 20120321632
    Abstract: The present invention is directed to pharmaceutical compositions containing one or more neutralizing prolactin receptor antibodies and antigen binding fragments, and their use in the treatment or prevention of benign disorders and indications mediated by the prolactin receptor such as endometriosis, adenomyosis, non-hormonal female contraception, benign breast disease and mastalgia, lactation inhibition, benign prostate hyperplasia, fibroids, hyper- and normoprolactinemic hair loss, and cotreatment in combined hormone therapy to inhibit mammary epithelial cell proliferation. The composition of the invention blocks prolactin receptor-mediated signaling.
    Type: Application
    Filed: November 18, 2010
    Publication date: December 20, 2012
    Applicant: BAYER INTELLECTUAL PROPERTY GMBH
    Inventors: Christiane Otto, Siegmund Wolf, Christoph Freiberg, Axel Harrenga, Simone Greven, Mark Trautwein, Sandra Bruder, Andrea Eicker, Andreas Wilmen
  • NEUTRALIZING PROLACTIN RECEPTOR ANTIBODIES AND THEIR THERAPEUTIC USE
    Publication number: 20120315276
    Abstract: The present invention is directed to the neutralizing prolactin receptor antibody 002-H08, and antigen binding fragments, pharmaceutical compositions containing them and their use in the treatment or prevention of benign disorders and indications mediated by the prolactin receptor such as endometriosis, adenomyosis, non-hormonal female contraception, benign breast disease and mastalgia, lactation inhibition, benign prostate hyperplasia, fibroids, hyper- and normoprolactinemic hair loss, and cotreatment in combined hormone therapy to inhibit mammary epithelial cell proliferation. The antibodies of the invention block prolactin receptor-mediated signaling.
    Type: Application
    Filed: November 18, 2010
    Publication date: December 13, 2012
    Applicant: BAYER INTELLECTUAL PROPERTY GMBH
    Inventors: Christiane Otto, Siegmund Wolf, Christoph Freiberg, Axel Harrenga, Simone Greven, Mark Trautwein, Sandra Bruder
  • Cinnamic acid amides
    Publication number: 20090149528
    Abstract: The present invention relates to compounds, to processes for preparing them, to pharmaceutical compositions comprising them, and to their use in the therapy and/or prophylaxis in illnesses in people or animals, especially diseases of bacterial infection.
    Type: Application
    Filed: July 2, 2008
    Publication date: June 11, 2009
    Applicant: Bayer HealthCare AG
    Inventors: Nina Brunner, Christoph Freiberg, Thomas Lampe, Ben Newton, Michael Otteneder, Joseph Pernerstorfer, Jens Pohlmann, Guido Schiffer, Mitsuyuki Shimada, Niels Svenstrup, Rainer Endermann, Peter Nell
  • Derivatives of andrimide and moiramide B having antibacterial properties
    Patent number: 7544709
    Abstract: The invention relates to compounds of general formula (I), to a method for the production thereof, to pharmaceutical compositions containing them, and to their use in the treatment and/or prophlaxis of diseases in humans or animals, particularly bacterial infections diseases. The compounds are derivatives of the natural substances andrimide and moiramide B.
    Type: Grant
    Filed: November 7, 2002
    Date of Patent: June 9, 2009
    Assignee: Bayer Healthcare AG
    Inventors: Nina Brunner, Christoph Freiberg, Thomas Lampe, Ben Newton, Michael Otteneder, Josef Pernerstorfer, Jens Pohlmann, Guido Schiffer, Mitsuyuki Shimada
  • Antibacterial amide macrocycles IV
    Patent number: 7446102
    Abstract: The invention relates to antibacterial amide macrocycles and processes for their preparation, their use for the treatment and/or prophylaxis of diseases and their use for the manufacture of medicaments for the treatment and/or prophylaxis of diseases, especially bacterial infections.
    Type: Grant
    Filed: March 23, 2007
    Date of Patent: November 4, 2008
    Assignee: AiCuris GmbH & Co. KG
    Inventors: Rainer Endermann, Kerstin Ehlert, Christoph Freiberg, Siegfried Raddatz, Martin Michels, Yolanda Cancho-Grande, Joachim Schuhmacher, Stefan Weigand
  • Cinnamic acid amides
    Patent number: 7402683
    Abstract: The present invention relates to compounds, to processes for preparing them, to pharmaceutical compositions comprising them, and to their use in the therapy and/or prophylaxis in illnesses in people or animals, especially diseases of bacterial infection.
    Type: Grant
    Filed: April 14, 2003
    Date of Patent: July 22, 2008
    Assignee: Bayer HealthCare AG
    Inventors: Nina Brunner, Christoph Freiberg, Thomas Lampe, Ben Newton, Michael Otteneder, Josef Pernerstorfer, Jens Pohlmann, Guido Schiffer, Mitsuyuki Shimada, Niels Svenstrup, Rainer Endermann, Peter Nell
  • ANTIBACTERIAL AMIDE MACROCYCLES IV
    Publication number: 20080076745
    Abstract: The invention relates to antibacterial amide macrocycles and processes for their preparation, their use for the treatment and/or prophylaxis of diseases and their use for the manufacture of medicaments for the treatment and/or prophylaxis of diseases, especially bacterial infections.
    Type: Application
    Filed: March 23, 2007
    Publication date: March 27, 2008
    Inventors: Rainer Endermann, Kerstin Ehlert, Christoph Freiberg, Siegfried Raddatz, Martin Michels, Yolanda Cancho-Grande, Joachim Schuhmacher, Stefan Weigand
  • Arylamides
    Patent number: 7348357
    Abstract: The present invention relates to compounds, to processes for preparing them, to pharmaceutical compositions comprising them, and to their use in the therapy and/or prophylaxis of diseases in people or animals, especially diseases of bacterial infection.
    Type: Grant
    Filed: July 28, 2003
    Date of Patent: March 25, 2008
    Assignee: Bayer HealthCare AG
    Inventors: Nina Brunner, Christoph Freiberg, Thomas Lampe, Peter Nell, Ben Newton, Michael Otteneder, Josef Pernerstorfer, Jens Pohlmann, Guido Schiffer, Mitsuyuki Shimada, Niels Svenstrup, Rainer Endermann
  • Cinnamic acid amides
    Publication number: 20060178369
    Abstract: The present invention relates to compounds, to processes for preparing them, to pharmaceutical compositions comprising them, and to their use in the therapy and/or prophylaxis in illnesses in people or animals, especially diseases of bacterial infection.
    Type: Application
    Filed: April 14, 2003
    Publication date: August 10, 2006
    Inventors: Nina Brunner, Christoph Freiberg, Thomas Lampe, Ben Newton, Michael Otteneder, Josef Pernerstorfer, Jens Pohlmann, Guido Schiffer, Mitsuyuki Shimada, Niels Svenstrup, Rainer Endermann
  • Arylamides
    Publication number: 20060173040
    Abstract: The present invention relates to compounds, to processes for preparing them, to pharmaceutical compositions comprising them, and to their use in the therapy and/or prophylaxis of diseases in people or animals, especially diseases of bacterial infection.
    Type: Application
    Filed: July 28, 2003
    Publication date: August 3, 2006
    Applicant: Bayer HealthCare AG
    Inventors: Nina Brunner, Christoph Freiberg, Thomas Lampe, Peter Nell, Ben Newton, Michael Otteneder, Josef Pernerstorfer, Jens Pohlmann, Guido Schiffer, Mitsuyuki Shimada, Niels Svenstrup, Rainer Endermann
  • Derivatives of andrimide and moiramide b having antibacterial properties
    Publication number: 20050080129
    Abstract: The invention relates to compounds of general formula (I), to a method for the production thereof, to pharmaceutical compositions containing them, and to their use in the treatment and/or prophlaxis of diseases in humans or animals, diseases. The compounds are derivatives of the natural substances andrimide and moiramide B.
    Type: Application
    Filed: November 7, 2002
    Publication date: April 14, 2005
    Applicant: Bayer HealthCare AG
    Inventors: Nina Brunner, Christoph Freiberg, Thomas Lampe, Ben Newton, Michael Otteneder, Josef Pernerstorfer, Jens Pohlmann, Guido Shiffer, Mitsuyuki Shimada