Abstract: Neural network performance is improved in terms of training speed and/or accuracy by encoding (mapping) inputs to the neural network into a higher dimensional space via a hash function. The input comprises coordinates used to identify a point within a d-dimensional space (e.g., 3D space). The point is quantized and a set of vertex coordinates corresponding to the point are input to a hash function. For example, for d=3, space may be partitioned into axis-aligned voxels of identical size and vertex coordinates of a voxel containing the point are input to the hash function to produce a set of encoded coordinates. The set of encoded coordinates is used to lookup D-dimensional feature vectors in a table of size T that have been learned. The learned feature vectors are filtered (e.g., linearly interpolated, etc.) based on the coordinates of the point to compute a feature vector corresponding to the point.

Abstract: Embodiments described herein pertain to a machine-learning approach for shading. A system may determine a number of pixels associated with a viewpoint of a viewer. The system may determine, for each of the pixels, (1) a view direction based on the viewpoint and a pixel position of that pixel and (2) and a surface orientation of a surface visible to that pixel. The system may generate, using a first machine-learning model, a latent space representation of ambient lighting information associated with the pixels based on respective view directions and surface orientations. The system may determine color values for the pixels by processing the latent space representation of ambient lighting information using a second machine-learning model.

Abstract: The present invention relates to a compound for use in the treatment or prevention of a liver disease, wherein the compound is a amyloid beta related protein, the amyloid beta related protein being selected from the group consisting of amyloid beta protein, a amyloid beta peptide derived therefrom, amyloid precursor protein (APP), a compound involved in the generation of an amyloid beta peptide from APP, or a compound inhibiting the degradation of the amyloid beta protein or of amyloid peptides derived therefrom.

Abstract: Embodiments described herein pertain to a machine-learning approach for shading. A system may determine, for each of a plurality of pixels, object visibility information based on one or more objects in a virtual environment. The system may select, for each pixel, a light source from a plurality of light sources in the virtual environment. The system may determine, for each pixel, lighting information associated with the light source selected for that pixel based on the associated object visibility information. The system may generate a first latent representation of the lighting information associated with the plurality of pixels. The system may generate a second latent representation by processing the first latent representation using a first machine-learning model trained to denoise latent light representations. The system may then generate color values for the plurality of pixels by processing at least the second latent representation using a second machine-learning model.

Abstract: A grilling device has a body, a cooking grate and a charcoal grate. The charcoal grate has a top side and a bottom side, is permeable to air, and has at least two parts. The at least two parts are tiltably arranged and, in the tilted position, form a space for fuel. The charcoal grate has holes on the top side and on the bottom side.

Abstract: A communication channel for reconfiguration of a device, such as an FPGA, is described in various embodiments. One embodiment includes a physical input/output circuit, a dynamic layer, and a static layer. The static layer is programmed into the reconfigurable device to contain a configuration layer and a network layer. The configuration layer is able to receive additional layers, such as a virtual network layer and a virtual security layer and program them into the reconfigurable device. The virtual network layer can provide communication protocols, such as TCP/IP, and the virtual security layer can provide security protocols, such as TLS and IPSec. Various distributed applications can be programmed into the reconfigurable device over the network and configured to use the virtual network layer and the virtual security layer.

Abstract: A communication channel for reconfiguration of a device, such as an FPGA, is described in various embodiments. One embodiment includes a physical input/output circuit, a dynamic layer, and a static layer. The static layer is programmed into the reconfigurable device to contain a configuration layer and a network layer. The configuration layer is able to receive additional layers, such as a virtual network layer and a virtual security layer and program them into the reconfigurable device. The virtual network layer can provide communication protocols, such as TCP/IP, and the virtual security layer can provide security protocols, such as TLS and IPSec. Various distributed applications can be programmed into the reconfigurable device over the network and configured to use the virtual network layer and the virtual security layer.

Abstract: Provided herein are methods of diagnosing and/or treating ACVS, by determining expression levels of several ACVS-related molecules, such as FABP3, ANPR-1, IGFBP-3, F9, SELL, apoB100, ADPN, vWF, THBS1, PRL, PON3, EGFR, VEGF-D, HPX, MBT, F5, F10, SERPIN A5, HCII, and HABP2, for example in a blood sample.

Abstract: Disclosed herein are embodiments of a system and method for preparing matrix-coated samples for analysis using mass spectrometry. In particular disclosed embodiments, the system and methods of using the system utilize an electric field to enhance results obtained from mass spectrometric analysis of the matrix-coated samples. The methods disclosed herein can be used to prepare biological samples that have improved characteristics facilitating the detection, localization, and/or identification of biomarkers for disease.

Abstract: A method for designing a stage for an axial turbomachine having a guide blade ring and a rotor blade ring arranged downstream of the guide blade ring is provided. The method includes: profiling a guide blade ring having guide blades arranged regularly over the circumference of the guide blade ring in accordance with basic aerodynamic and mechanical conditions; moving at least one profile section of at least one of the guide blades in the circumferential direction in such a way that the pitch angle for the at least one guide blade and a guide blade arranged adjacent thereto varies over the blade height in such a way that during operation of the axial turbomachine the departing flow formed downstream of the guide blade ring is irregularly formed over the circumference of the axial turbomachine, such that the vibration excitation of the rotor blades of the rotor blade ring is low.

Abstract: Disclosed herein are embodiments of a system and method for preparing matrix-coated samples for analysis using mass spectrometry. In particular disclosed embodiments, the system and methods of using the system utilize an electric field to enhance results obtained from mass spectrometric analysis of the matrix-coated samples. The methods disclosed herein can be used to prepare biological samples that have improved characteristics facilitating the detection, localization, and/or identification of biomarkers for disease.

Abstract: The present invention relates to a method for the in vitro selection of at least one therapeutic cell subpopulation from an original cell population of eukaryotic cells, as well as to the therapeutic cell subpopulation selected by the method, which can be used for the treatment of diseases of tissues or organs. The selected cells are highly migrative and the method according to the invention provides for the selection of these highly migrative subpopulations from a sample comprising a mixture of cells.

Abstract: The present invention relates to a method for the in vitro selection of at least one therapeutic cell subpopulation from an original cell population of eukaryotic cells, as well as to the therapeutic cell subpopulation selected by the method, which can be used for the treatment of diseases of tissues or organs. The selected cells are highly migrative and the method according to the invention provides for the selection of these highly migrative subpopulations from a sample comprising a mixture of cells.

Abstract: An imaging system (100) includes a radiation source (112) that emits radiation that traverses an examination region and a detector array (114) with a plurality of photon counting detector pixels (116) that detect radiation traversing the examination region and respectfully generate a signal indicative of the detected radiation. The photon counting detector pixel includes a direct conversion layer (122) having a first radiation receiving side (202) and second opposing side (206), a cathode (118) affixed to and covering all of or a substantial portion of the first side, an anode (120) affixed to a centrally located region (208) of the second side, wherein the anode includes at least two sub-anodes (120, 120i, 1202, 120N), and a metallization (124) affixed to the second side, surrounding the anode and the anode region, with a gap between the anode and the metallization.

Abstract: A method for designing a stage for an axial turbomachine having a guide blade ring and a rotor blade ring arranged downstream of the guide blade ring is provided. The method includes: profiling a guide blade ring having guide blades arranged regularly over the circumference of the guide blade ring in accordance with basic aerodynamic and mechanical conditions; moving at least one profile section of at least one of the guide blades in the circumferential direction in such a way that the pitch angle for the at least one guide blade and a guide blade arranged adjacent thereto varies over the blade height in such a way that during operation of the axial turbomachine the departing flow formed downstream of the guide blade ring is irregularly formed over the circumference of the axial turbomachine, such that the vibration excitation of the rotor blades of the rotor blade ring is low.

Abstract: A turbine blade fastening is provided. The turbine blade fastening include a blade root implemented in a fir tree design, which includes anchoring teeth implemented toward the blade casting tip such that the height of the anchoring teeth is reduced toward the blade casting tip. The anchoring teeth are designed for fitting into corresponding recesses in a rotor.