Patents by Inventor Christoph Hoh

Christoph Hoh has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Cleavage of precursors of insulins by a variant of trypsin
    Patent number: 7981635
    Abstract: The present invention relates to the production of a variant of recombinant trypsin with increased substrate specificity for arginine versus lysine in non-animal host organisms. Moreover, the present invention relates to a variant of recombinant trypsin and their production. Also provided are use of recombinant porcine pancreatic trypsin variants for cleavage of precursors of insulins, and kits containing the variant of trypsin.
    Type: Grant
    Filed: August 26, 2006
    Date of Patent: July 19, 2011
    Assignees: Sanofi-Aventis Deutschland GmbH, Roche Diagnostics Operations, Inc.
    Inventors: Frank Zocher, Christoph Hoh, Rainer Mueller, Erhard Kopetzki, Frank Geipel, Stephan Glaser
  • CLEAVAGE OF PRECURSORS OF INSULINS BY A VARIANT OF TRYPSIN
    Publication number: 20100196953
    Abstract: The present invention relates to the production of a variant of recombinant trypsin with increased substrate specificity for arginine versus lysine in non-animal host organisms. Moreover, the present invention relates to a variant of recombinant trypsin and their production. Also provided are use of recombinant porcine pancreatic trypsin variants for cleavage of precursors of insulins, and kits containing the variant of trypsin.
    Type: Application
    Filed: August 26, 2006
    Publication date: August 5, 2010
    Applicants: SANOFI-AVENTIS DEUTSCHLAND GMBH, F. HOFFMAN-LA ROCHE AG
    Inventors: Frank Geipel, Stephan Glaser, Christoph Hoh, Erhard Kopetzki, Rainer Mueller, Frank Zocher