Patents by Inventor Christoph Koellner

Christoph Koellner has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • SYNTHESIS OF BORONIC ESTER AND ACID COMPOUNDS
    Publication number: 20220204558
    Abstract: The invention relates to the synthesis of boronic ester and acid compounds. More particularly, the invention provides improved synthetic processes for the large-scale production of boronic ester and acid compounds, including the peptide boronic acid proteasome inhibitor bortezomib.
    Type: Application
    Filed: March 14, 2022
    Publication date: June 30, 2022
    Inventors: Vince Ammoscato, John E. Bishop, Fang-Ting Chiu, Achim Geiser, Jean-Marc Gomez, Robert Hett, Christoph Koellner, Vithalanand R. Kulkami, Young Lo, Stephen Munk, I. Fraser Pickersgill
  • SYNTHESIS OF BORONIC ESTER AND ACID COMPOUNDS
    Publication number: 20210395301
    Abstract: The invention relates to the synthesis of boronic ester and acid compounds. More particularly, the invention provides improved synthetic processes for the large-scale production of boronic ester and acid compounds, including the peptide boronic acid proteasome inhibitor bortezomib.
    Type: Application
    Filed: September 2, 2021
    Publication date: December 23, 2021
    Inventors: Vince Ammoscato, John E. Bishop, Fang-Ting Chiu, Achim Geiser, Jean-Marc Gomez, Robert Hett, Christoph Koellner, Vithalanand R. Kulkarni, Young Lo, Stephen Munk, I. Fraser Pickersgill
  • SYNTHESIS OF BORONIC ESTER AND ACID COMPOUNDS
    Publication number: 20210171574
    Abstract: The invention relates to the synthesis of boronic ester and acid compounds. More particularly, the invention provides improved synthetic processes for the large-scale production of boronic ester and acid compounds, including the peptide boronic acid proteasome inhibitor bortezomib.
    Type: Application
    Filed: February 19, 2021
    Publication date: June 10, 2021
    Inventors: Vince Ammoscato, John E. Bishop, Fang-Ting Chiu, Achim Geiser, Jean-Marc Gomez, Robert Hett, Christoph Koellner, Vithalanand R. Kulkarni, Young Lo, Stephen Munk, I. Fraser Pickersgill
  • SYNTHESIS OF BORONIC ESTER AND ACID COMPOUNDS
    Publication number: 20200369722
    Abstract: The invention relates to the synthesis of boronic ester and acid compounds. More particularly, the invention provides improved synthetic processes for the large-scale production of boronic ester and acid compounds, including the peptide boronic acid proteasome inhibitor bortezomib.
    Type: Application
    Filed: August 13, 2020
    Publication date: November 26, 2020
    Inventors: Vince Ammoscato, John E. Bishop, Fang-Ting Chiu, Achim Geiser, Jean-Marc Gomez, Robert Hett, Christoph Koellner, Vithalanand R. Kulkarni, Young Lo, Stephen Munk, I. Fraser Pickersgill
  • SYNTHESIS OF BORONIC ESTER AND ACID COMPOUNDS
    Publication number: 20200157143
    Abstract: The invention relates to the synthesis of boronic ester and acid compounds. More particularly, the invention provides improved synthetic processes for the large-scale production of boronic ester and acid compounds, including the peptide boronic acid proteasome inhibitor bortezomib.
    Type: Application
    Filed: January 24, 2020
    Publication date: May 21, 2020
    Inventors: Vince Ammoscato, John E. Bishop, Fang-Ting Chiu, Achim Geiser, Jean-Marc Gomez, Robert Hett, Christoph Koellner, Vithalanand R. Lulkarni, Young Lo, Stephen Munk, I.Fraser Pickersgill
  • SYNTHESIS OF BORONIC ESTER AND ACID COMPOUNDS
    Publication number: 20190330270
    Abstract: The invention relates to the synthesis of boronic ester and acid compounds. More particularly, the invention provides improved synthetic processes for the large-scale production of boronic ester and acid compounds, including the peptide boronic acid proteasome inhibitor bortezomib.
    Type: Application
    Filed: July 11, 2019
    Publication date: October 31, 2019
    Inventors: Vince Ammoscato, John E. Bishop, Fang-Ting Chiu, Achim Geiser, Jean-Marc Gomez, Robert Hett, Christoph Koellner, Vithalanand R. Kulkarni, Young Lo, Stephen Munk, I. Fraser Pickersgill
  • SYNTHESIS OF BORONIC ESTER AND ACID COMPOUNDS
    Publication number: 20190112334
    Abstract: The invention relates to the synthesis of boronic ester and acid compounds. More particularly, the invention provides improved synthetic processes for the large-scale production of boronic ester and acid compounds, including the peptide boronic acid proteasome inhibitor bortezomib.
    Type: Application
    Filed: December 13, 2018
    Publication date: April 18, 2019
  • SYNTHESIS OF BORONIC ESTER AND ACID COMPOUNDS
    Publication number: 20180265546
    Abstract: The invention relates to the synthesis of boronic ester and acid compounds. More particularly, the invention provides improved synthetic processes for the large-scale production of boronic ester and acid compounds, including the peptide boronic acid proteasome inhibitor bortezomib.
    Type: Application
    Filed: May 23, 2018
    Publication date: September 20, 2018
  • Synthesis of boronic ester and acid compounds
    Patent number: 10000529
    Abstract: The invention relates to the synthesis of boronic ester and acid compounds. More particularly, the invention provides improved synthetic processes for the large-scale production of boronic ester and acid compounds, including the peptide boronic acid proteasome inhibitor bortezomib.
    Type: Grant
    Filed: September 22, 2017
    Date of Patent: June 19, 2018
  • SYNTHESIS OF BORONIC ESTER AND ACID COMPOUNDS
    Publication number: 20180044377
    Abstract: The invention relates to the synthesis of boronic ester and acid compounds. More particularly, the invention provides improved synthetic processes for the large-scale production of boronic ester and acid compounds, including the peptide boronic acid proteasome inhibitor bortezomib.
    Type: Application
    Filed: September 22, 2017
    Publication date: February 15, 2018
  • Synthesis of boronic ester and acid compounds
    Patent number: 9862745
    Abstract: The invention relates to the synthesis of boronic ester and acid compounds. More particularly, the invention provides improved synthetic processes for the large-scale production of boronic ester and acid compounds, including the peptide boronic acid proteasome inhibitor bortezomib.
    Type: Grant
    Filed: January 8, 2016
    Date of Patent: January 9, 2018
  • SYNTHESIS OF BORONIC ESTER AND ACID COMPOUNDS
    Publication number: 20160362449
    Abstract: The invention relates to the synthesis of boronic ester and acid compounds. More particularly, the invention provides improved synthetic processes for the large-scale production of boronic ester and acid compounds, including the peptide boronic acid proteasome inhibitor bortezomib.
    Type: Application
    Filed: January 8, 2016
    Publication date: December 15, 2016
  • SYNTHESIS OF BORONIC ESTER AND ACID COMPOUNDS
    Publication number: 20150038706
    Abstract: The invention relates to the synthesis of boronic ester and acid compounds. More particularly, the invention provides improved synthetic processes for the large-scale production of boronic ester and acid compounds, including the peptide boronic acid proteasome inhibitor bortezomib.
    Type: Application
    Filed: March 6, 2014
    Publication date: February 5, 2015
  • Methods for the synthesis of pyridoxamine
    Patent number: 8431712
    Abstract: The invention provides non-oxidative methods for the large scale manufacture of pyridoxamine (I) (4-aminomethyl-3-hydroxy-5-hydroxymethyl-2-methylpyridine): and salts thereof. The invention also provides intermediate compounds for the synthesis of pyridoxamine, as well as compositions and methods for the treatment and/or prevention of conditions associated with the formation of post-Amadori advanced glycation end-products.
    Type: Grant
    Filed: August 12, 2010
    Date of Patent: April 30, 2013
    Assignee: NephroGenex, Inc.
    Inventors: Raja G. Khalifah, Roland Keilitz, Christoph Koellner, Thorsten Degenhardt, Stephen Robert Brand
  • SYNTHESIS OF BORONIC ESTER AND ACID COMPOUNDS
    Publication number: 20130005968
    Abstract: The invention relates to the synthesis of boronic ester and acid compounds. More particularly, the invention provides improved synthetic processes for the large-scale production of boronic ester and acid compounds, including the peptide boronic acid proteasome inhibitor bortezomib.
    Type: Application
    Filed: September 14, 2012
    Publication date: January 3, 2013
  • Synthesis of boronic ester and acid compounds
    Patent number: 8283467
    Abstract: The invention relates to the synthesis of boronic ester and acid compounds. More particularly, the invention provides improved synthetic processes for the large-scale production of boronic ester and acid compounds, including the peptide boronic acid proteasome inhibitor bortezomib.
    Type: Grant
    Filed: February 16, 2010
    Date of Patent: October 9, 2012
  • Methods for the Synthesis of Pyridoxamine
    Publication number: 20100305162
    Abstract: The invention provides non-oxidative methods for the large scale manufacture of pyridoxamine (I) (4-aminomethyl-3-hydroxy-5-hydroxymethyl-2-methylpyridine): and salts thereof. The invention also provides intermediate compounds for the synthesis of pyridoxamine, as well as compositions and methods for the treatment and/or prevention of conditions associated with the formation of post-Amadori advanced glycation end-products.
    Type: Application
    Filed: August 12, 2010
    Publication date: December 2, 2010
    Inventors: Raja Khalifah, Roland Keilitz, Christoph Koellner, Thorsten Degenhardt, Stephen Robert Brand
  • SYNTHESIS OF BORONIC ESTER AND ACID COMPOUNDS
    Publication number: 20100174072
    Abstract: The invention relates to the synthesis of boronic ester and acid compounds. More particularly, the invention provides improved synthetic processes for the large-scale production of boronic ester and acid compounds, including the peptide boronic acid proteasome inhibitor bortezomib.
    Type: Application
    Filed: February 16, 2010
    Publication date: July 8, 2010
  • Synthesis of boronic ester and acid compounds
    Patent number: 7714159
    Abstract: The invention relates to the synthesis of boronic ester and acid compounds. More particularly, the invention provides improved synthetic processes for the large-scale production of boronic ester and acid compounds, including the peptide boronic acid proteasome inhibitor bortezomib.
    Type: Grant
    Filed: March 24, 2005
    Date of Patent: May 11, 2010
  • Methods for the synthesis of pyridoxamine
    Publication number: 20070161678
    Abstract: The invention provides non-oxidative methods for the large scale manufacture of pyridoxamine (I) (4-aminomethyl-3-hydroxy-5-hydroxymethyl-2-methylpyridine): (I), and salts thereof. The invention also provides intermediate compounds for the synthesis of pyridoxamine, as well as compositions and methods for the treatment and/or prevention of conditions associated with the formation of post-Amadori advanced glycation end-products.
    Type: Application
    Filed: March 16, 2007
    Publication date: July 12, 2007
    Inventors: Raja Khalifah, Roland Keilitz, Christoph Koellner, Thorsten Degenhardt, Stephen Brand