Patents by Inventor Christoph Kratky

Christoph Kratky has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Isolated protein having hydroxynitrile lyase activity
    Patent number: 7202075
    Abstract: New genes containing a DNA sequence coding for hydroxynitrile lyase, which genes can be prepared via a primer combination based on the DNA sequence of the 5?-region of the mdl genes from the Prunus serotina and from Prunus amygdalus and/or a primer 2 based on the 3?-region of the DNA sequences of one of the hydroxynitrile lyase isoenzymes from Prunus serotina or from Prunus amygdalus, subsequent amplification with a DNA polymerase using a DNA from organisms, containing genes coding for hydroxynitrile lyase, as templates and cloning, and also recombinant proteins which can be prepared in suitable host cells by heterologous expression of the DNA sequence of said HNL genes, and proteins and fusion proteins derived therefrom and use of said proteins for preparing (R)- or (S)-cyanohydrins.
    Type: Grant
    Filed: September 15, 2004
    Date of Patent: April 10, 2007
    Assignee: DSM Fine Chemicals Austria NFG GmbH & Co KG
    Inventors: Helmut Schwab, Anton Glieder, Christoph Kratky, Ingrid Dreveny, Rodolfo Bona, Peter Pöchlauer, Wolfgang Skranc, Herbert Mayrhofer, Irma Wirth, Rudolf Neuhofer
  • Genes containing a DNA sequence coding for hydroxynitrile lyase, recombinant proteins derived therefrom and having hydroxynitrile lyase activity, and use thereof
    Publication number: 20050064552
    Abstract: New genes containing a DNA sequence coding for hydroxynitrile lyase, which genes can be prepared via a primer combination based on the DNA sequence of the 5?-region of the mdl genes from the Prunus serotina and from Prunus amygdalus and/or a primer 2 based on the 3?-region of the DNA sequences of one of the hydroxynitrile lyase isoenzymes from Prunus serotina or from Prunus amygdalus, subsequent amplification with a DNA polymerase using a DNA from organisms, containing genes coding for hydroxynitrile lyase, as templates and cloning, and also recombinant proteins which can be prepared in suitable host cells by heterologous expression of the DNA sequence of said HNL genes, and proteins and fusion proteins derived therefrom and use of said proteins for preparing (R)- or (S)-cyanohydrins.
    Type: Application
    Filed: September 15, 2004
    Publication date: March 24, 2005
    Inventors: Helmut Schwab, Anton Glieder, Christoph Kratky, Ingrid Dreveny, Rodolfo Bona, Peter Pochlauer, Wolfgang Skranc, Herbert Mayrhofer, Irma Wirth, Rudolf Neuhofer
  • Genes containing a DNA sequence coding for hydroxynitrile lyase, recombinant proteins derived therefrom and having hydroxynitrile lyase activity, and use thereof
    Patent number: 6861243
    Abstract: New genes containing a DNA sequence coding for hydroxynitrile lyase, which genes can be prepared via a primer combination based on the DNA sequence of the 5?-region of the mdl genes from Prunus serotina and from Prunus amygdalus and/or a primer 2 based on the 3?-region of the DNA sequences of one of the hydroxynitrile lyase isoenzymes from Prunus serotina or from Prunus amygdalus, subsequent amplification with a DNA polymerase using a DNA from organisms, containing genes coding for hydroxynitrile lyase, as templates and cloning, and also recombinant proteins which can be prepared in suitable host cells by heterologous expression of the DNA sequence of said HNL genes, and proteins and fusion proteins derived therefrom and use of said proteins for preparing (R)- or (S)-cyanohydrins.
    Type: Grant
    Filed: January 16, 2002
    Date of Patent: March 1, 2005
    Assignee: DSM Fine Chemicals Austria NFG GmbH & Co. KG
    Inventors: Helmut Schwab, Anton Glieder, Christoph Kratky, Ingrid Dreveny, Peter Pöchlauer, Wolfgang Skranc, Herbert Mayrhofer, Irma Wirth, Rudolf Neuhofer, Rodolfo Bona
  • Genes containing a DNA sequence coding for hydroxynitrile lyase, recombinant proteins derived therefrom and having hydroxynitrile lyase activity, and use thereof
    Publication number: 20030119099
    Abstract: New genes containing a DNA sequence coding for hydroxynitrile lyase, which genes can be prepared via a primer combination based on the DNA sequence of of the 5′-region of the mdl genes from Prunus serotina and from Prunus amygdalus and/or a primer 2 based on the 3′-region of the DNA sequences of one of the hydroxynitrile lyase isoenzymes from Prunus serotina or from Prunus amygdalus, subsequent amplification with a DNA polymerase using a DNA from organisms, containing genes coding for hydroxynitrile lyase, as templates and cloning, and also recombinant proteins which can be prepared in suitable host cells by heterologous expression of the DNA sequence of said HNL genes, and proteins and fusion proteins derived therefrom and use of said proteins for preparing (R)- or (S)-cyanohydrins.
    Type: Application
    Filed: January 16, 2002
    Publication date: June 26, 2003
    Inventors: Helmut Schwab, Anton Glieder, Christoph Kratky, Ingrid Dreveny, Peter Pochlauer, Wolfgang Skranc, Herbert Mayrhofer, Irma Wirth, Rudolf Neuhofer, Rodolfo Bona
  • (S)-hydroxynitrile lyases with improved substrate acceptance and their use
    Patent number: 6319697
    Abstract: (S)-Hydroxynitrile lyases which have an improved substrate acceptance and which are derived from the Hevea brasiliensis and Manihot esculenta (S)-hydroxynitrile lyases, wherein one or more bulky amino acid residues within the hydrophobic channel leading to the active center have been replaced with less bulky amino acid residues.
    Type: Grant
    Filed: July 1, 1999
    Date of Patent: November 20, 2001
    Assignee: DSM Fine Chemicals Austria GmbH
    Inventors: Franz Effenberger, Harald Wajant, Peter Lauble, Siegfried Förster, Holger Buhler, Helmut Schwab, Christoph Kratky, Ulrike Wagner, Ernst Steiner