Patents by Inventor Christoph L. BAUSCH

Christoph L. BAUSCH has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Ungulate-derived polyclonal immunoglobulin specific for coronavirus protein and uses thereof
    Patent number: 11975066
    Abstract: Provided are human polyclonal immunoglobulin products for use in treating or preventing coronavirus disease. Further provided are methods for making such compositions in a transgenic ungulate, e.g. using a transchromosomic bovine (TcB) system.
    Type: Grant
    Filed: June 30, 2021
    Date of Patent: May 7, 2024
    Assignee: SAB Biotherapeutics, Inc.
    Inventors: Tom Luke, Christoph L. Bausch, Eddie J. Sullivan, Hua Wu, Kristi A. Egland
  • UNGULATE-DERIVED POLYCLONAL IMMUNOGLOBULIN SPECIFIC FOR EGFR AND USES THEREOF
    Publication number: 20240010734
    Abstract: Provided are human polyclonal immunoglobulin products specific for Epidermal Growth Factor Receptor (EGFR) for use in treating or preventing cancer. Further provided are methods for making such compositions in a transgenic ungulate, e.g. using a transchromosomic bovine (TcB) system.
    Type: Application
    Filed: November 12, 2021
    Publication date: January 11, 2024
    Applicant: SAB, LLC
    Inventors: Hua WU, Eddie J. SULLIVAN, Kristi A. Egland, Christoph L. BAUSCH
  • ANTI-THYMOCYTE GLOBULIN
    Publication number: 20240002486
    Abstract: Provided are human anti-thymocyte globulin (ATG) products, and methods of making and using the same. In particular, the disclosure provides an ungulate-derived polyclonal immunoglobulin, comprising a population of fully human or substantially human immunoglobulins. The population of fully human or substantially human immunoglobulins specifically binds human thymocytes, T cells, B cells, and/or monocytes. Such compositions may be made by immunization of transgenic animals having a human Ig locus with human thymocyte. This method generates polyclonal immunoglobulin with yield, purity, and antigen specificity that enable use of this product in medical applications.
    Type: Application
    Filed: August 28, 2023
    Publication date: January 4, 2024
    Inventors: Eddie J. SULLIVAN, Hua WU, Christoph L. BAUSCH
  • UNGULATE-DERIVED POLYCLONAL IMMUNOGLOBULIN SPECIFIC FOR PD-LI AND USES THEREOF
    Publication number: 20230406934
    Abstract: Provided are human polyclonal immunoglobulin products specific for Programmed Death-Ligand 1 (PD-L1) for use in treating or preventing cancer. Further provided are methods for making such compositions in a transgenic ungulate, e.g. using a transchromosomic bovine (TcB) system.
    Type: Application
    Filed: November 12, 2021
    Publication date: December 21, 2023
    Applicant: SAB, LLC
    Inventors: Christoph L. BAUSCH, Hua Wu, Kristi A. EGLAND, Eddie J. SULLIVAN
  • UNGULATE-DERIVED POLYCLONAL IMMUNOGLOBULIN SPECIFIC FOR CORONAVIRUS PROTEIN AND USES THEREOF
    Publication number: 20220062405
    Abstract: Provided are human polyclonal immunoglobulin products for use in treating or preventing coronavirus disease. Further provided are methods for making such compositions in a transgenic ungulate, e.g. using a transchromosomic bovine (TcB) system.
    Type: Application
    Filed: June 30, 2021
    Publication date: March 3, 2022
    Inventors: Tom LUKE, Christoph L. BAUSCH, Eddie J. SULLIVAN, Hua WU, Kristi A. EGLAND
  • ANTI-THYMOCYTE GLOBULIN
    Publication number: 20210246197
    Abstract: Provided are human anti-thymocyte globulin (ATG) products, and methods of making and using the same. In particular, the disclosure provides an ungulate-derived polyclonal immunoglobulin, comprising a population of fully human or substantially human immunoglobulins. The population of fully human or substantially human immunoglobulins specifically binds human thymocytes, T cells, B cells, and/or monocytes. Such compositions may be made by immunization of transgenic animals having a human Ig locus with human thymocyte. This method generates polyclonal immunoglobulin with yield, purity, and antigen specificity that enable use of this product in medical applications.
    Type: Application
    Filed: February 9, 2021
    Publication date: August 12, 2021
    Inventors: Eddie J. SULLIVAN, Hua WU, Christoph L. BAUSCH