Patents by Inventor Christoph M. Dehnhardt

Christoph M. Dehnhardt has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Process for the synthesis of cPLA inhibitors
    Patent number: 7582771
    Abstract: A process for making the compound of formula (I) wherein Ac represents acetate; X represents O or CH2; Y represents C1-C6alkyl; and Z is selected from the group consisting of H, halogen, CN, CHO, CF3, OCF3, OH, C1-C6alkyl, C1-C6alkoxy, C1-C6thioalkyl, NH2, N(C1-C6alkyl)2, NH(C1-C6alkyl), NC(O)—(C1C6alkyl), and NO2. In his process, a compound of formula (II) is reacted with hydrazine to form a primary alkylamine, and then the primary alkylamine is reacted with acetic anhydride, to produce the compound of formula (I).
    Type: Grant
    Filed: August 31, 2004
    Date of Patent: September 1, 2009
    Assignee: Wyeth
    Inventors: Christoph M. Dehnhardt, Sreenivasulu Megati, Ronald S. Michalak, Panolil Raveendranath, Jianxin Ren, Charles C. Wu, Yangzhong Wu
  • Process for the Synthesis of a CPLA2 Inhibitor
    Publication number: 20080177085
    Abstract: A process for making a substituted indole compound, including the steps of: reacting the compounds in a non-protic polar solvent in the presence of a catalyst to form the intermediate compound wherein Ph and X are as defined herein; and then, heating this intermediate compound in the solvent in the presence of the catalyst to form the substituted indole compound The invention also includes compounds formed by this process.
    Type: Application
    Filed: March 4, 2008
    Publication date: July 24, 2008
    Inventors: Christoph M. Dehnhardt, Sreenivasulu Megati, Ronald S. Michalak, Panolil Raveendranath
  • Process for the synthesis of a CPLAinhibitor
    Patent number: 7342119
    Abstract: A process for making a substituted indole compound, including the steps of: reacting the compounds in a non-protic polar solvent in the presence of a catalyst to form the intermediate compound wherein Ph and X are as defined herein; and then, heating this intermediate compound in the solvent in the presence of the catalyst to form the substituted indole compound The invention also includes compounds formed by this process.
    Type: Grant
    Filed: September 23, 2004
    Date of Patent: March 11, 2008
    Inventors: Christoph M. Dehnhardt, Sreenivasulu Megati, Ronald S. Michalak, Panolil Raveendranath