Patents by Inventor Christoph Martin Stahl

Christoph Martin Stahl has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • NOVEL SULFONAMIDES AS L-CPT1 INHIBITORS
    Publication number: 20120232104
    Abstract: The invention is concerned with novel sulfonamide derivatives of formula (I) wherein R2, R3, R4, A, X, Y1, Y2, Y3, Y4 and Z1 are as defined in the description and in the claims, as well as physiologically acceptable salts and esters thereof. These compounds inhibit L-CPT1 and can be used as medicaments.
    Type: Application
    Filed: May 22, 2012
    Publication date: September 13, 2012
    Inventors: Konrad Bleicher, Simona Maria Ceccarelli, Odile Chomienne, Patrizio Mattei, Tanja Schulz-Gasch, Christoph Martin Stahl
  • NOVEL SULFONAMIDES AS L-CPT1 INHIBITORS
    Publication number: 20110319438
    Abstract: The invention is concerned with novel sulfonamide derivatives of formula (I) wherein R2, R3, R4, A, X, Y1, Y2, Y3, Y4 and Z1 are as defined in the description and in the claims, as well as physiologically acceptable salts and esters thereof. These compounds inhibit L-CPT1 and can be used as medicaments.
    Type: Application
    Filed: September 7, 2011
    Publication date: December 29, 2011
    Inventors: Konrad Bleicher, Simona Maria Ceccarelli, Odile Chomienne, Patrizio Mattei, Tanja Schulz-Gasch, Christoph Martin Stahl
  • NOVEL SULFONAMIDES AS L-CPT1 INHIBITORS
    Publication number: 20100144762
    Abstract: The invention is concerned with novel sulfonamide derivatives of formula (I) wherein R2, R3, R4, A, X, Y1, Y2, Y3, Y4 and Z1 are as defined in the description and in the claims, as well as physiologically acceptable salts and esters thereof. These compounds inhibit L-CPT1 and can be used as medicaments.
    Type: Application
    Filed: February 8, 2010
    Publication date: June 10, 2010
    Inventors: Konrad Bleicher, Simona Maria Ceccarelli, Odile Chomienne, Patrizio Mattei, Tanja Schulz-Gasch, Christoph Martin Stahl
  • Sulfonamides as L-CPT1 inhibitors
    Patent number: 7723538
    Abstract: The invention is concerned with novel sulfonamide derivatives of formula (I) wherein R2, R3, R4, A, X, Y1, Y2, Y3, Y4 and Z1 are as defined in the description and in the claims, as well as physiologically acceptable salts and esters thereof. These compounds inhibit L-CPT1 and can be used as medicaments.
    Type: Grant
    Filed: June 1, 2006
    Date of Patent: May 25, 2010
    Assignee: Hoffmann-La Roche Inc.
    Inventors: Konrad Bleicher, Simona Maria Ceccarelli, Odile Chomienne, Patrizio Mattei, Tanja Schulz-Gasch, Christoph Martin Stahl
  • DICARBOXAMIDE DERIVATIVES
    Publication number: 20090270360
    Abstract: The invention is concerned with novel dicarboxamide derivatives of formula (I) wherein A, B, Rc, D and E are as defined in the description and in the claims, as well as physiologically acceptable salts thereof. These compounds inhibit the coagulation factor Xa and can be used as medicaments.
    Type: Application
    Filed: January 16, 2009
    Publication date: October 29, 2009
    Inventors: Markus Boehringer, Katrin Groebke Zbinden, Wolfgang Haap, Hans Hilpert, Jacques Himber, Roland Humm, Hans Iding, Dietmar Knopp, Narendra Panday, Fabienne Ricklin, Christoph Martin Stahl
  • Pyrrolidine-3,4-dicarboxamide derivatives
    Patent number: 7550487
    Abstract: The invention is concerned with novel pyrrolidine-3,4-dicarboxamide derivatives of formula (I) wherein R1 to R9 and X are as defined in the description and in the claims, as well as physiologically acceptable salts thereof. These compounds inhibit the coagulation factor Xa and can be used as medicaments.
    Type: Grant
    Filed: March 9, 2005
    Date of Patent: June 23, 2009
    Assignee: Hoffmann-La Roche Inc.
    Inventors: Lilli Anselm, Katrin Groebke Zbinden, Wolfgang Haap, Jacques Himber, Christoph Martin Stahl, Stefan Thomi
  • Dicarboxamide derivatives
    Patent number: 7501413
    Abstract: The invention is concerned with novel dicarboxamide derivatives of formula (I) wherein A, B, Rc, D and E are as defined in the description and in the claims, as well as physiologically acceptable salts thereof. These compounds inhibit the coagulation factor Xa and can be used as medicaments.
    Type: Grant
    Filed: October 31, 2005
    Date of Patent: March 10, 2009
    Assignee: Hoffmann-La Roche Inc.
    Inventors: Markus Boehringer, Katrin Groebke Zbinden, Wolfgang Haap, Hans Hilpert, Jacques Himber, Roland Humm, Hans Iding, Dietmar Knopp, Narendra Panday, Fabienne Ricklin, Christoph Martin Stahl
  • Substituted quinazoline compounds useful as p38 kinase inhibitors
    Patent number: 7456185
    Abstract: Compounds having the formula (I), are useful as p38 kinase inhibitors, wherein R4 and R5 are hydrogen, halogen, cyano, haloalkyl, or haloalkoxy, but are not both hydrogen; R6 and R7 are optional substituents, and Q is a non-aromatic moiety as defined in the specification.
    Type: Grant
    Filed: March 27, 2007
    Date of Patent: November 25, 2008
    Assignee: Roche Palo Alto LLC
    Inventors: James Patrick Dunn, David Michael Goldstein, Christoph Martin Stahl, Teresa Alejandra Trejo-Martin
  • 6-Substituted pyrido-pyrimidines
    Patent number: 7449581
    Abstract: The present invention provides compounds of the Formula I and II: wherein R1, R3, W, Z, X1, X2, Ar1, R8 and R9 are as defined herein, and methods and intermediates for their preparation and uses thereof.
    Type: Grant
    Filed: January 9, 2007
    Date of Patent: November 11, 2008
    Assignee: Poche Palo Alto LLC
    Inventors: Jian Jeffrey Chen, James Patrick Dunn, David Michael Goldstein, Christoph Martin Stahl
  • Methods of inhibiting p38 with substituted bicyclic pyrimidines
    Patent number: 7449472
    Abstract: The present invention discloses compounds corresponding to the formula wherein A, X, Y, R, R1 and R2 are as defined within, pharmaceutical formulations, methods of making and uses thereof.
    Type: Grant
    Filed: August 12, 2005
    Date of Patent: November 11, 2008
    Assignee: Roche Palo Alto LLC
    Inventors: Jian Jeffrey Chen, Nolan James Dewdney, Christoph Martin Stahl
  • Bicyclic pyridine and pyrimidine P38 kinase inhibitors
    Patent number: 7439247
    Abstract: The present invention discloses compounds corresponding to formula wherein A, R, X, Y, R, R1 and R2 are as defined above, pharmaceutical formulations, methods of making and uses thereof.
    Type: Grant
    Filed: November 30, 2005
    Date of Patent: October 21, 2008
    Assignee: Roche Palo Altop LLC
    Inventors: Jian Jeffrey Chen, Nolan James Dewdney, Christoph Martin Stahl
  • Substituted quinazoline compounds useful as p38 kinase inhibitors
    Patent number: 7238698
    Abstract: Compounds having the formula (I), are useful as p38 kinase inhibitors, wherein R4 and R5 are hydrogen, halogen, cyano, haloalkyl, or haloalkoxy, but are not both hydrogen; R6 and R7 are optional substituents, and Q is a non-aromatic moiety as defined in the specification.
    Type: Grant
    Filed: April 15, 2004
    Date of Patent: July 3, 2007
    Assignee: Roche Palo Alto LLC
    Inventors: James Patrick Dunn, David Michael Goldstein, Christoph Martin Stahl, Teresa Alejandra Trejo-Martin
  • 6-substituted pyrido-pyrimidines
    Patent number: 7169794
    Abstract: The present invention provides compounds of the Formula I and II: wherein R1, R3, W, Z, X1, X2, Ar1, R8 and R9 are as defined herein, and methods and intermediates for their preparation and uses thereof.
    Type: Grant
    Filed: November 25, 2003
    Date of Patent: January 30, 2007
    Assignee: Roche Palo Alto LLC
    Inventors: Jian Jeffrey Chen, James Patrick Dunn, David Michael Goldstein, Christoph Martin Stahl
  • Mandelic acid derivatives
    Patent number: 7129238
    Abstract: The invention is concerned with novel mandelic acid derivatives of formula (I) wherein R1 to R10, X and Y are as defined in the description and in the claims, as well as pharmaceutically acceptable salts thereof. These compounds inhibit the formation of coagulation factors Xa, IXa and thrombin induced by factor VIIa and tissue factor.
    Type: Grant
    Filed: November 21, 2003
    Date of Patent: October 31, 2006
    Assignee: Hoffmann-La Roche Inc.
    Inventors: David William Banner, Luca Claudio Gobbi, Katrin Groebke Zbinden, Ulrike Obst, Christoph Martin Stahl
  • Bicyclic pyridine and pyrimidine p38 kinase inhibitors
    Patent number: 7091347
    Abstract: The present invention discloses compounds corresponding to formula wherein A, R, X, Y, R, R1 and R2 are as defined above, pharmaceutical formulations, methods of making and uses thereof.
    Type: Grant
    Filed: March 6, 2003
    Date of Patent: August 15, 2006
    Assignee: Roche Palo Alto LLC
    Inventors: Jian Jeffrey Chen, Nolan James Dewdney, Christoph Martin Stahl
  • Substituted quinazoline compounds useful as P38 kinase inhibitors
    Publication number: 20040209904
    Abstract: Compounds having the formula (I), 1
    Type: Application
    Filed: April 15, 2004
    Publication date: October 21, 2004
    Inventors: James Patrick Dunn, David Michael Goldstein, Christoph Martin Stahl, Teresa Alejandra Trejo-Martin
  • Novel mandelic acid derivatives
    Publication number: 20040122057
    Abstract: The invention is concerned with novel mandelic acid derivatives of formula (I) 1
    Type: Application
    Filed: November 21, 2003
    Publication date: June 24, 2004
    Inventors: David William Banner, Luca Claudio Gobbi, Katrin Groebke Zbinden, Ulrike Obst, Christoph Martin Stahl
  • 6-Substituted pyrido-pyrimidines
    Publication number: 20040116698
    Abstract: The present invention provides compounds of the Formula I and II: 1
    Type: Application
    Filed: November 25, 2003
    Publication date: June 17, 2004
    Inventors: Jian Jeffrey Chen, James Patrick Dunn, David Michael Goldstein, Christoph Martin Stahl
  • 6-substituted pyrido-pyrimidines
    Patent number: 6696566
    Abstract: The present invention provides compounds of the Formula I and II: wherein R1, R3, W, Z, X1, X2, Ar1, R8 and R9 are as defined herein, and methods and intermediates for their preparation and uses thereof.
    Type: Grant
    Filed: February 11, 2002
    Date of Patent: February 24, 2004
    Assignee: Syntex (U.S.A.) LLC
    Inventors: Jian Jeffrey Chen, James Patrick Dunn, David Michael Goldstein, Christoph Martin Stahl
  • Bicyclic pyridine and pyrimidine p38 kinase inhibitors
    Publication number: 20030207900
    Abstract: The present invention discloses compounds corresponding to formula 1
    Type: Application
    Filed: March 6, 2003
    Publication date: November 6, 2003
    Inventors: Jian Jeffrey Chen, Nolan James Dewdney, Christoph Martin Stahl