Patents by Inventor Christoph Methfessel

Christoph Methfessel has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 6984297
    Abstract: A method and a device are used for carrying out measurements on cells located in a liquid environment. Each cell is positioned with an underside of its membrane on a surface having a channel running through it. A negative pressure is established to aspirate the cells. Each cell is electrically scanned via at least one electrode which is spaced apart from the cell. The negative pressure is preferably established in a pulse-like manner to rupture the membrane in such a way that the cell interior enclosed by the membrane is connected to the channel.
    Type: Grant
    Filed: November 20, 2002
    Date of Patent: January 10, 2006
    Assignees: NMI Naturwissenschaftliches und Medizinisches Institut an der Universität Tübingen, Bayer AG
    Inventors: Wilfried Nisch, Martin Stelzle, Alfred Stett, Thomas Krahn, Thomas Müller, Christoph Methfessel
  • Publication number: 20050227139
    Abstract: The invention relates to a measuring arrangement for measuring electrical signals on biological membrane bodies, whereby an electroconductive acess into the membrane body is created by gap junction channels.
    Type: Application
    Filed: July 28, 2003
    Publication date: October 13, 2005
    Inventors: Christoph Methfessel, Frank Lison, Ingmar Dorn
  • Publication number: 20050209236
    Abstract: The invention relates to novel heteroaryl carboxamides, processes for their preparation, and their use for producing medicaments for the treatment and/or prophylaxis of diseases and for improving perception, concentration, learning and/or memory.
    Type: Application
    Filed: November 6, 2002
    Publication date: September 22, 2005
    Inventors: Martin Hendrix, Frank-Gerhard Boss, Christina Erb, Joachim Kruger, Joachim Luithle, Christoph Methfessel, Rudy Schreiber, Welf-Burkhard Wiese
  • Publication number: 20050154045
    Abstract: The invention relates to novel 1-aza-bicyclic N-biarylamides, methods for production and use thereof for the production of medicaments for the treatment and/or prophylaxis of diseases and for improving perception, concentration, learning ability and memory.
    Type: Application
    Filed: March 3, 2003
    Publication date: July 14, 2005
    Applicant: Bayer Healthcare AG
    Inventors: Joachim Luithle, Frank-Gerhard Boss, Christiana Erb, Katrin Schnizler, Timo Flessner, Marja Kampen, Christoph Methfessel, Frank-Thorsten Hafner
  • Publication number: 20050119325
    Abstract: The invention relates to novel 2-heteroarylcarboxamides, processes for their preparation, and their use for producing medicaments for the treatment and/or prophylaxis of diseases and for improving perception, concentration, learning and/or memory.
    Type: Application
    Filed: December 16, 2002
    Publication date: June 2, 2005
    Inventors: Martin Hendrix, Frank-Gerhard Boss, Christina Erb, Timo Flessner, Marja Kampen, Joachim Luithle, Christoph Methfessel, Welf-Burkhard Wiese
  • Publication number: 20050107460
    Abstract: The invention relates to novel bicylic N-arylamides, to a method for the production thereof, and to the use of the same for producing pharmaceuticals for the treatment and/or prophylaxis of diseases and for improving perception, power of concentration, learnig capacity and/or memory retention.
    Type: Application
    Filed: December 6, 2002
    Publication date: May 19, 2005
    Inventors: Joachim Luithle, Frank-Gerhard Boss, Christina Erb, Timo Flessner, Martin Hendrix, Marja Kampen, Christoph Methfessel
  • Publication number: 20050048671
    Abstract: A device for spatially separating a biochemical activity from a detection reaction that detects the biochemical activity. The device comprises a first membrane body comprising the biochemical activity, and a second membrane body comprising the detection reaction. The first and second membrane bodies each comprise lipid bilayers, wherein the first and second membrane bodies are connected by gap junctions.
    Type: Application
    Filed: August 5, 2004
    Publication date: March 3, 2005
    Applicant: Bayer Technology Services GmbH
    Inventors: Christoph Methfessel, John Goossens
  • Publication number: 20050009820
    Abstract: The invention relates to novel thiochromenones and processes for their preparation, to their use for the treatment and/or prophylaxis of diseases, especially for the treatment and/or prophylaxis of states of pain and neurodegenerative disorders.
    Type: Application
    Filed: May 21, 2002
    Publication date: January 13, 2005
    Inventors: Heinrich Meier, Swen Allerheilingen, Michael Gerisch, Rudolfd Schohe-Loop, Arnd Voerste, Frank Mauler, Jean Marie de Vry, Thomas Muller, Christoph Methfessel
  • Publication number: 20030219884
    Abstract: The present invention relates to a method for carrying out electrical measurements on biological membrane bodies, which are located on a substrate. The electrically conductive access to the membrane body, which is needed for the measurement, is made in situ by intense laser beams.
    Type: Application
    Filed: January 30, 2003
    Publication date: November 27, 2003
    Applicant: Bayer Aktiengesellschaft
    Inventors: Frank Lison, Christoph Methfessel, Katrin Schnizler
  • Publication number: 20030080314
    Abstract: A method and a device are used for carrying out measurements on cells located in a liquid environment. Each cell is positioned with an underside of its membrane on a surface having a channel running through it. A negative pressure is established to aspirate the cells. Each cell is electrically scanned via at least one electrode which is spaced apart from the cell. The negative pressure is preferably established in a pulse-like manner to rupture the membrane in such a way that the cell interior enclosed by the membrane is connected to the channel.
    Type: Application
    Filed: November 20, 2002
    Publication date: May 1, 2003
    Inventors: Wilfried Nisch, Martin Stelzle, Alfred Stett, Thomas Krahn, Thomas Muller, Christoph Methfessel
  • Publication number: 20020150975
    Abstract: The present invention relates to a peptide having the amino acid sequence 1 Leu Thr Cys Leu Asn Cys Pro Glu Met Phe   1             5                10 Cys Gly Lys Phe Gln Ile Cys Arg Asn Gly                15                20 Glu Lys Ile Cys Phe Lys Lys Leu His Gln                25                30 Arg Arg Pro Leu Ser Trp Arg Tyr Ile Arg                35                40 Gly Cy
    Type: Application
    Filed: July 23, 2001
    Publication date: October 17, 2002
    Inventors: Christoph Methfessel, Viktor Tsetlin, Yuri Utkin
  • Publication number: 20020146765
    Abstract: The invention relates to modified acetylcholine receptor subunits, to nucleic acids coding modified acetylchloine receptor subunits, and to methods for finding active ingredients for crop protection and active pharmaceutical ingredients for treating humans and/or animals.
    Type: Application
    Filed: August 27, 2001
    Publication date: October 10, 2002
    Inventors: Martin Adamczewski, Ulrich Ebbinghaus-Kintscher, Christoph Methfessel, Thomas Schulte
  • Publication number: 20020046412
    Abstract: The invention relates to nucleic acids which encode insect acetylcholine receptor &bgr; subunits, and to polypeptides which exert the biological function of such acetylcholine receptor &bgr; subunits, and in particular to their use for finding active compounds for crop protection.
    Type: Application
    Filed: December 8, 2000
    Publication date: April 18, 2002
    Inventors: Martin Adamczewski, Christoph Methfessel, Thomas Schulte
  • Patent number: 5547965
    Abstract: The invention relates to the use of substituted amines for the treatment and prevention of brain function disorders. The substituted amines are suitable on the basis of their properties as agonistic or antagonistic ligands for nicotinergic receptors, in particular for the treatment and prevention of senile and presenile dementia and dementia of the Alzheimer type, and of depressions.
    Type: Grant
    Filed: April 19, 1995
    Date of Patent: August 20, 1996
    Assignee: Bayer Aktiengesellschaft
    Inventors: Bernd-Wieland Kr uger, Fritz Maurer, Christoph Methfessel, Klaus Tietjen, Alfred Maelicke, Bernard Schmidt, Kozo Shiokawa