Patents by Inventor Christoph Rosenbohn

Christoph Rosenbohn has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Method for preparation of LNA phosphoramidites
    Patent number: 7153954
    Abstract: The present invention relates to large scale preparation of LNA phosphoramidites using a 2-cyanoethyl-N,N,N?,N?-tetra-substituted phosphoramidite and a nucleophilic activator, e.g. 2-cyanoethyl-N,N,N?,N?-tetraisopropylphosphoramidite and 4,5-dicyanoimidazole. The method is faster and more cost efficient that previously known methods.
    Type: Grant
    Filed: July 12, 2002
    Date of Patent: December 26, 2006
    Assignee: Santaris Pharma A/S
    Inventors: Troels Koch, Christoph Rosenbohn, Daniel Sejer Pedersen