Abstract: A method for generating a continuous carrier gas/vapour mixture stream containing a carrier gas, and a vapour of a liquid. The method includes provision of a first metered carrier gas stream, provision of a second metered carrier gas stream, provision of a metered, vapour-saturated carrier gas/vapour mixture stream, mixing of the second stream and the metered stream to provide a first gaseous mixture stream; and provision of a metered liquid stream fed to an evaporation/mixing device for evaporating the liquid and mixing with the first gaseous mixture stream to provide a second gaseous mixture stream.

Abstract: A piston/damper tube assembly may include a damper tube with damping fluid, a movable piston rod, a working piston, a controllable 4-way bottom valve with a control member, and a compensation space. Two flow passage ways of the bottom valve connect the working space remote from the piston rod via the control member to the compensation space. Two control ways of the bottom valve load the control member on a first side with a pressure of the piston rod-side working space and on a second side with a pressure of the compensation space. The control member may control the flow passage ways in a manner dependent on the pressure of the piston-rod-side working space that prevails on the control member on the first side via a fluidic connection, and on the pressure of the compensation space that prevails on the control member on the second side via an opening.

Abstract: The present invention relates to a process for printing multicoloured printed images in which exclusively interference pigments are used for the coloured pigmentation of the printing inks, to printed products produced using a process of this type, to the use thereof, and to suitable interference pigments.

Abstract: The present invention relates to recombinant factor H and variants and conjugates thereof and methods of their production, as well as uses and methods of treatment involving the materials.

Abstract: A pigment mixture comprising at least two or three interference pigments of different interference colours selected from the colours red, green and blue, suitable for use in paints, coatings, printing inks, security printing inks, plastics, ceramic materials, glasses and in the preparation of pigment preparations, dry preparations and in particular cosmetic formulations.

Abstract: A piston/damper tube assembly may include a damper tube with damping fluid, a movable piston rod, a working piston, a controllable 4-way bottom valve with a control member, and a compensation space. Two flow passage ways of the bottom valve connect the working space remote from the piston rod via the control member to the compensation space. Two control ways of the bottom valve load the control member on a first side with a pressure of the piston rod-side working space and on a second side with a pressure of the compensation space. The control member may control the flow passage ways in a manner dependent on the pressure of the piston-rod-side working space that prevails on the control member on the first side via a fluidic connection, and on the pressure of the compensation space that prevails on the control member on the second side via an opening.

Abstract: The present invention relates to a multi-domain polypeptide comprising (i) a first complement control protein repeat (CCP)-comprising domain being a convertase decay accelerating domain for convertases of the classical and alternative pathways of complement activation, (ii) a host cell recognition domain, and (iii) a second CCP-comprising domains with cofactor activity. The present invention further relates to a polynucleotide encoding said multi-domain polypeptide, to a vector comprising said polynucleotide, and to a host cell comprising said polynucleotide and/or said vector. Further, the present invention relates to the multi-domain polypeptide, the polypeptide, and the vector for use in medicine and for treating and/or preventing inappropriate complement activation and/or a disease having inappropriate complement activation as a symptom. Moreover, the present invention relates to methods and uses related to multi-domain polypeptide, the polypeptide, and the vector.

Abstract: The present invention provides polymersomes comprising non-biodegradable amphiphilic block-copolymers and their enteral (e.g., oral) or topical use in the treatment of an ammonia or ammonia methylated analog-associated disease or disorder or symptom thereof (e.g., hyperammonemia or trimethylaminuria). More particularly, it provides a polymersome comprising (a) a membrane, which comprises a block copolymer of poly(styrene) (PS) and poly(ethylene oxide) (PEO), wherein the PS/PEO molecular weight ratio is higher than 1.0 and lower than 4.0; and (b) a core which encloses an acid. It also provides a method of making the polymersome comprising mixing the copolymer-containing organic solvent phase with an aqueous phase containing the acid.

Abstract: A gas mask is provided with a mask body, which is designed to cover the face of a user, and with an opening in the mask body, which is closed by a speech diaphragm (8) in a gas-tight manner. A funnel (4) is directed toward the speech diaphragm with an opening angle in the range of 20° to 90°. The funnel (4) is arranged in front of the speech diaphragm in the interior space of the mask body in order to focus sound waves onto the speech diaphragm.

Abstract: The invention relates to a stacking spacer for a photovoltaic module frame, to a photovoltaic module frame, and to a tracking device assembly for said photovoltaic module frame and stacking spacer. The stacking spacer comprises a main body extending in a longitudinal direction, a connecting member, extending in said longitudinal direction and protruding from said main body, adapted for being inserted at least one lateral profile groove of said photovoltaic module frame and two opposed support members, arranged on respective opposed longitudinal sides of said main body, extending in said longitudinal direction, wherein the two opposed support members have complementary forms, whereby at least two stacking spacers can be securely stacked on top of each other.

Abstract: A method for generating a continuous carrier gas/vapour mixture stream containing a carrier gas, and a vapour of a liquid. The method includes provision of a first metered carrier gas stream, provision of a second metered carrier gas stream, provision of a metered, vapour-saturated carrier gas/vapour mixture stream, mixing of the second stream and the metered stream to provide a first gaseous mixture stream; and provision of a metered liquid stream fed to an evaporation/mixing device for evaporating the liquid and mixing with the first gaseous mixture stream to provide a second gaseous mixture stream.

Abstract: The present invention relates to interference pigments based on multicoated flake-form substrates which have on the surface of the substrate a layer sequence comprising (A0) optionally a high-refractive-index coating consisting of a layer of TiO2, (A) a high-refractive-index coating consisting of a mixture of TiO2 and Fe2O3, which may optionally be doped with one or more further oxides, (B) a high-refractive-index layer consisting of SnO2, (C) a high-refractive-index coating which absorbs in the visible wavelength region, and optionally (D) an outer protective layer, and to the use thereof, in particular in paints, coatings, industrial coatings, automobile paints, automotive refinish paints, coil coating, powder coatings, printing inks, plastics, pigment pastes, pigment preparations and in dry preparations, such as, for example, granules.

Abstract: The present invention relates to a process for printing multicoloured printed images in which exclusively interference pigments are used for the coloured pigmentation of the printing inks, to printed products produced using a process of this type, to the use thereof, and to suitable interference pigments.

Abstract: The present invention relates to recombinant factor H and variants and conjugates thereof and methods of their production, as well as uses and methods of treatment involving the materials.

Abstract: A driver assistance system enables accelerate awareness of a danger source by the driver of a motor vehicle. The driver assistance system includes a display field that, from the viewpoint of the driver, is larger than a primary field of vision, which can be scanned without eye movement on the part of the vehicle driver. The driver assistance system also includes a control unit for displaying signs at different locations in the display field, and a hazard detection unit for detecting at least the direction in which a hazard outside the vehicle is located from the viewpoint of the driver. The control unit is configured to first display a preliminary signal in a preferred direction from the viewpoint of the driver, and then to display at least a first follow-up signal in an intermediate direction between the preferred direction and the direction in which the danger source is located.

Abstract: The present invention relates to five-layered pigments based on multi-coated platelet-shaped substrates which comprise a layer sequence comprising (A) a layer of SnO2 having a layer thickness of 0.1-50 nm, (B) a high-refractive-index coating consisting of TiO2 in the rutile modification having a layer thickness of 10-800 nm, (C) a colorless coating having a refractive index n?1.8 having a layer thickness of 20-800 nm, (D) a high-refractive-index coating consisting of SnO2 having a layer thickness of 0.1-50 nm, (E) a layer of TiO2 in the rutile modification having a layer thickness of 10-800 nm, and optionally (F) an outer protective layer, and to the use thereof in paints, coatings, powder coatings, printing inks, security printing inks, plastics, ceramic materials, glasses, as dopants for the laser marking of papers and plastics, in cosmetic formulations and for the preparation of pigment preparations and dry preparations.

Abstract: Pharmaceutically acceptable solubilizing compositions comprising (i) at least one tocopheryl compound having a polyalkylene glycol moiety and (ii) at least one alkylene glycol fatty acid monoester or mixture of alkylene glycol fatty acid mono-and diester are disclosed. The solubilizing compositions are useful in the manufacture of pharmaceutical dosage forms comprising a melt-processed mixture of at least one active ingredient and at least one pharmaceutically acceptable polymer. The solubilizing compositions enhance the bioavailability of the active ingredient following oral intake.

Abstract: Filler pigments based on platelet-shaped substrates, which are coated with barium sulfate and at least two metal oxides and/or metal hydroxides are highly suitable as filler pigments especially for cosmetic formulations.

Abstract: A potent complement regulator is disclosed. The complement regulator comprises a complement regulatory region connected by a flexible linker to a multifunctional binding region that enables binding to C3b activation/inactivation products and/or oxidation end products, as well as to polyanionic surface markers on host cells. An embodiment of the invention utilizes factor H SCRs 1-4 as the complement regulatory region and factor H SCRs 19 and 20 as the multifunctional binding region, linked together by a poly-Gly linker at least 12 residues in length. Pharmaceutical compositions comprising the complement regulator and methods of using the complement regulator are also disclosed.

Abstract: A process for producing a solid dispersion of an active ingredient which comprises feeding the active ingredient and a matrix-forming agent to an extruder and forming a uniform extrudate, wherein the extruder comprises at least two rotating shafts (2), each of the shafts (2) carrying a plurality of processing elements disposed axially one behind the other, the processing elements defining (i) a feeding and conveying section (R; A), (ii) at least one reverse-flight section (D), and (iii) a discharging section (E), wherein the processing elements defining the reverse-flight section (R; D) comprise at least one reverse-flight element (14) which is based on a screw-type element having a conveying direction being opposite to the general conveying direction of the extruder.