Patents by Inventor Christoph Uherek

Christoph Uherek has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • AGENT FOR TREATING DISEASE
    Publication number: 20110059082
    Abstract: The present invention provides a pharmaceutical composition for treating an autoimmune disease comprising a pharmaceutically acceptable carrier and an agent capable of activating CD4+CD25+ regulatory T cells, wherein the composition is to be administered to a subject in a dose of the agent from 10 mg to 200 mg.
    Type: Application
    Filed: September 13, 2010
    Publication date: March 10, 2011
    Inventors: Matthias Germer, Frank Osterroth, Silke Aigner, Christoph Uherek, Elmar Kraus, Andrea Wartenberg-Demand, Daniele Wolf, Sibylle Kaiser, Juergen Lindner, Christoph Bruecher, Benjamin Daelken
  • AGENT FOR TREATING DISEASE
    Publication number: 20110059084
    Abstract: The present invention provides a pharmaceutical composition for treating an autoimmune disease comprising a pharmaceutically acceptable carrier and an agent capable of activating CD4+CD25+ regulatory T cells, wherein the composition is to be administered to a subject in a dose of the agent from 0.2 mg to 30 mg.
    Type: Application
    Filed: September 13, 2010
    Publication date: March 10, 2011
    Inventors: FRANK OSTERROTH, SILKE AIGNER, MATTHIAS GERMER, CHRISTOPH UHEREK, ELMAR KRAUS, ANDREA WARTENBERG-DEMAND, DANIELE WOLF, SIBYLLE KAISER, JUERGEN LINDNER, CHRISTOPH BRUECHER, BENJAMIN DAELKEN
  • AGENT FOR TREATING DISEASE
    Publication number: 20110059083
    Abstract: The present invention provides pharmaceutical composition for treating an autoimmune disease comprising a pharmaceutically acceptable carrier and an agent capable of activating CD4+CD25+ regulatory T cells, wherein the composition is to be administered to a subject at most every 3 days.
    Type: Application
    Filed: September 13, 2010
    Publication date: March 10, 2011
    Inventors: SILKE AIGNER, MATTHIAS GERMER, FRANK OSTERROTH, CHRISTOPH UHEREK, ELMAR KRAUS, ANDREA WARTENBERG-DEMAND, DANIELE WOLF, SIBYLLE KAISER, JUERGEN LINDNER, CHRISTOPH BRUECHER, BENJAMIN DAELKEN
  • IMMUNOCONJUGATES TARGETING CD138 AND USES THEREOF
    Publication number: 20090232810
    Abstract: Disclosed are immunoconjugates having in particular specificity for CD138 expressed on target cells and which display homogenous targeting. The immunoconjugates may be sterially hindered and/or contain a cleavable linker.
    Type: Application
    Filed: December 23, 2008
    Publication date: September 17, 2009
    Inventors: Elmar Kraus, Christoph Bruecher, Benjamin Daelken, Steffen Zeng, Frank Osterroth, Christoph Uherek, Silke Aigner, Matthias Germer
  • METHOD OF DECREASING CYTOTOXIC SIDE-EFFECTS AND IMPROVING EFFICACY OF IMMUNOCONJUGATES
    Publication number: 20090181038
    Abstract: Disclosed are methods, compositions and kits for improving targeting, in particular tumor targeting, of immunoconjugates. The method and composition relies on the sequestration of non-target cells that also express the antigen the immunoconjugate targets. Sequestration of those non-target cells in a variety of ways is disclosed. The methods, compositions and kits allow appropriate sequestration of non-target cells while maintaining a high degree of effectiveness of the immunoconjugates against target cells.
    Type: Application
    Filed: December 23, 2008
    Publication date: July 16, 2009
    Inventors: Gregor Schulz, Christoph Bruecher, Frank Osterroth, Steffen Zeng, Christoph Uherek, Silke Aigner, Benjamin Daelken, Markus Ruehle, Elmar Kraus
  • AGENTS TARGETING CD138 AND USES THEREOF
    Publication number: 20090175863
    Abstract: Disclosed is a human murine chimeric antibody which substantially retains the antigen binding region of its murine counterpart and displays improved binding affinities to the antigen and/or more homogenous binding to target cells.
    Type: Application
    Filed: December 23, 2008
    Publication date: July 9, 2009
    Inventors: Elmar Kraus, Christoph Bruecher, Benjamin Daelken, Matthias Germer, Steffen Zeng, Frank Osterroth, Christoph Uherek, Silke Aigner
  • METHODS AND AGENTS FOR IMPROVING TARGETING OF CD138 EXPRESSING TUMOR CELLS
    Publication number: 20090169570
    Abstract: Disclosed are immunoconjugates having specificity for CD138 that diminish adhesion of CD138 expressing tumor cells to stroma cells and methods of using the same. This diminished adhesion renders the tumor cells not only susceptible to the immunoconjugate, but also to other agents, in particular cytotoxic agents.
    Type: Application
    Filed: December 23, 2008
    Publication date: July 2, 2009
    Inventors: Benjamin Daelken, Christoph Uherek, Kenneth Anderson, Teru Hideshima, Christoph Bruecher