Patents by Inventor Christoph Wittmann
Christoph Wittmann has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 11931558Abstract: A device for administering a fluid product includes a first housing part with a receiver for the product, a second housing part detachably connectable to the first housing part, a piston rod held such that it can be displaced for the exertion of an emptying movement, an actuatable or releasable drive element for the piston rod, a coupling element including a coupling input element that couples the drive element to the piston rod in a coupling engagement, transmits a driving force of the drive element to the piston rod, and triggers the emptying movement, and a decoupling element displaceably connected to the second housing part and coupled to the first housing part such that it is displaced, by a movement of the housing parts in relation to each other when the housing parts are separated into a decoupling position wherein the piston rod is decoupled from the coupling input element.Type: GrantFiled: July 7, 2021Date of Patent: March 19, 2024Assignee: Ypsomed AGInventors: Philippe Kohlbrenner, Daniel Kuenzli, Christoph Meier, Peter Stettler, Juergen Wittmann, Martin Wittwer
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Publication number: 20240068226Abstract: A combination of an anchor rail with a hammer head element for setting in concrete. In order to achieve the best possible load-carrying capacity in the longitudinal direction L of the anchor rail, the anchor rail has toothing, specifically in a region close to a slot-like opening for the insertion of the hammer head element. The hammer head element, in a force-free state, rests only on the toothing and comes to rest over an entire head upper side only in the case of increased tensile forces, as a result of which the force transmission moves outwards to side walls of the anchor rail. This facilitates the load-carrying capacity of the anchor rail with respect to tensile forces.Type: ApplicationFiled: March 3, 2022Publication date: February 29, 2024Applicant: fischerwerke GmbH & Co. KGInventors: Roland UNTERWEGER, Christoph WIEDNER, Falk WITTMANN
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Publication number: 20220348615Abstract: The present invention relates to the production of bacteriocins, and in particular the production of bacteriocins of class I or II by recombinant expression in coryneform bacteria as the bacterial cell host. Also provided are modified coryneform bacteria for use as production hosts for production of bacteriocins.Type: ApplicationFiled: April 20, 2022Publication date: November 3, 2022Applicants: Norwegian University of Science and Technology (NTNU), UNIVERSITÄT ULM, NORWEGIAN UNIVERSITY OF LIFE SCIENCES, DANMARKS TEKNISKE UNIVERSITET, UNIVERSITÄT DES SAARLANDESInventors: Gerd Michael SEIBOLD, Christoph WITTMANN, Dzung DIEP, Nadav BAR, Christian U. REIDEL, Dominik WEIXLER, Oliver GOLDBECK
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Patent number: 11279955Abstract: Described herein is a process of producing an organic compound, the process including: I) cultivating a genetically modified microorganism in a culture medium including sucrose as an assimilable carbon source to allow the genetically modified microorganism to produce the organic compound, and II) recovering the organic compound from the fermentation broth obtained in process step I) The genetically modified microorganism includes A) at least one genetic modification that leads to an increased activity of the enzyme encoded by the rbsK-gene, compared to the original microorganism that has not been genetically modified, and the original microorganism belongs to the family Pasteurellaceae. Also described herein are a genetically modified microorganism and the use thereof for the fermentative production of an organic compound from sucrose as an assimilable carbon source.Type: GrantFiled: May 18, 2018Date of Patent: March 22, 2022Assignee: BASF SEInventors: Hartwig Schroeder, Stefan Haefner, Oskar Zelder, Christoph Wittmann, Anna Christine Schroer, Birgit Hoff, Nico Boehmer
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Publication number: 20200181653Abstract: Described herein is a process of producing an organic compound, the process including: I) cultivating a genetically modified microorganism in a culture medium including sucrose as an assimilable carbon source to allow the genetically modified microorganism to produce the organic compound, and II) recovering the organic compound from the fermentation broth obtained in process step I) The genetically modified microorganism includes A) at least one genetic modification that leads to an increased activity of the enzyme encoded by the rbsK-gene, compared to the original microorganism that has not been genetically modified, and the original microorganism belongs to the family Pasteurellaceae. Also described herein are a genetically modified microorganism and the use thereof for the fermentative production of an organic compound from sucrose as an assimilable carbon source.Type: ApplicationFiled: May 18, 2018Publication date: June 11, 2020Inventors: Hartwig Schroeder, Stefan Haefner, Oskar Zelder, Christoph Wittmann, Anna Christine Schroer, Birgit Hoff, Nico Boehmer
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Publication number: 20200017771Abstract: Conversion of organic educts, in particular biomass feedstock, into useful organic compounds via pyrolysis and bio-catalysts.Type: ApplicationFiled: March 8, 2018Publication date: January 16, 2020Inventors: Christoph Wittmann, Jost Van Duuren, Michael Kohlstedt, Jessica Stolzenberger, Soeren Starck, Nadja Barton, Mirjam Selzer, Michael Fritz, Paul De Wild, Martin Kuhl, Judith Becker
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Patent number: 10520488Abstract: A method for determination of the growth rate of biofilm using an electrical impedance analyses is disclosed. The method comprises the steps of: bringing a culture medium fluid in contact to an electrode structure, having biofilm grown within the fluid culture medium with the biofilm arranged in distance to the electrodes structure, so that the fluid culture medium is placed between the growing biofilm and the electrode structure; measuring the impedance of the electrodes structure over a monitoring time, and determining the growth rate of the biofilm as a function of the reduction rate of the impedance values measured on the electrode structure.Type: GrantFiled: December 18, 2015Date of Patent: December 31, 2019Assignee: Helmholtz-Zentrum fuer Infektionsforschung GmbHInventors: Jost Van Duuren, Blanka Karge, Christoph Wittmann, Mark Broenstrup
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Patent number: 10287558Abstract: The present invention relates to a modified microorganism having, compared to its wild-type, a reduced activity of the enzyme that is encoded by the pykA-gene. The present invention also relates to a method for producing an organic compound and to the use of modified microorganisms.Type: GrantFiled: February 2, 2015Date of Patent: May 14, 2019Assignee: BASF SEInventors: Joanna Martyna Krawczyk, Stefan Haefner, Hartwig Schröder, Esther Dantas Costa, Oskar Zelder, Gregory Von Abendroth, Christoph Wittmann, René Stellmacher, Judith Becker, Anna Lange, Benjamin J. Lyons, Thomas J. Lyons, Eudes De Crecy, Ewa Hughes
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Patent number: 10273485Abstract: The present invention relates to a modified microorganism having, compared to its wild-type, a reduced activity of the enzyme that is encoded by the wcaJ-gene. The present invention also relates to a method for producing an organic compound and to the use of a modified microorganism.Type: GrantFiled: February 6, 2015Date of Patent: April 30, 2019Assignee: BASF SEInventors: Joanna Martyna Krawczyk, Stefan Haefner, Hartwig Schröder, Esther Dantas Costa, Oskar Zelder, Gregory Von Abendroth, Christoph Wittmann, René Stellmacher, Judith Becker
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Publication number: 20180282768Abstract: The present invention relates to the field of biotechnology. It involves the decomposition and conversion of organic educts, in particular biomass feedstock, lignin, guaiacol; p-coumaryl alcohol; coniferyl alcohol; sinapyl alcohol; cresol; phenol; catechol; polysaccharides; cellulose hemicellulose; xylose; glucose; fructose; proteins; amino acids; triacylglycerides and/or fatty acids into useful organic compounds with the help of biocatalysts. A method of producing an organic product comprises i) fluid-assisted decomposition of an organic educt under sub- or supercritical conditions ii) obtaining an intermediate product from step i) iii) subjecting the intermediate product to biocatalytic conversion, by contacting the intermediate product obtained in step ii) with a biocatalyst, wherein said biocatalyst is a host cell selected from the group consisting of bacteria, yeast, filamentous fungi, cyanobacteria, algae, and plant cells.Type: ApplicationFiled: August 29, 2016Publication date: October 4, 2018Inventors: Jozef van Duuren, Jessica Stolzenberger, Mich Kohlstedt, Sören Starck, Mirjam Selzer, Michel Fritz, Heike HöItzen, Rudolf Richter, Christoph Wittmann
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Patent number: 9915297Abstract: A clutch device has a counter-pressure plate and a contact plate which is movable to a limited extent in an axial direction of the clutch device by at least one lever element to clamp a clutch plate frictionally between the counter-pressure plate and the contact plate, wherein the counter-pressure plate has at least one strap segment extending essentially in an axial direction, to which a cover component is connected.Type: GrantFiled: October 14, 2013Date of Patent: March 13, 2018Assignee: Schaeffler Technologies AG & Co. KGInventors: Igor Loran, Christoph Raber, Christoph Wittmann
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Publication number: 20170350875Abstract: A method for determination of the growth rate of biofilm (7) using an electrical impedance analyses is disclosed. The method comprises the steps of: bringing a culture medium fluid (3) in contact to an electrode structure (4a, 4b), having biofilm (7) grown within the fluid culture medium (3) with the biofilm (7) arranged in distance to the electrodes structure (4a, 4b), so that the fluid culture medium (3) is placed between the growing biofilm (7) and the electrode structure (4a, 4b); measuring the impedance of the electrodes structure (4a, 4b) over a monitoring time, and determining the growth rate of the biofilm (7) as a function of the reduction rate of the impedance values measured on the electrode structure (4a, 4b).Type: ApplicationFiled: December 18, 2015Publication date: December 7, 2017Applicant: Helmholtz-Zentrum fuer Infektionsforschung GmbHInventors: Jost VAN DUUREN, Blanka KARGE, Christoph WITTMANN, Mark BROENSTRUP
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Patent number: 9745608Abstract: Recombinant microorganisms comprising DNA molecules in a deregulated form which improve the production of cadaverine or N-acetylcadaverine, as well as recombinant DNA molecules and polypeptides used to produce the microorganisms are provided. Said microorganisms comprise an intracellular lysine decarboxylase activity and a deregulated cadaverine export activity, or comprise a decreased cadaverine export activity and an enhanced N-acetylcadaverine forming activity. Processes for the production of cadaverine N-acetylcadaverine using the recombinant microorganisms are also provided.Type: GrantFiled: February 20, 2012Date of Patent: August 29, 2017Assignee: BASF SEInventors: Christoph Wittmann, Stefanie Kind
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Patent number: 9709570Abstract: The present invention relates to an isotope labeling chamber for labeling metabolites in an organism, comprising a reactor chamber (1) and an air regulation chamber (2), wherein the reactor chamber (1) comprises the following components: optionally, a housing frame (3), housing walls (4), at least one injection valve (5), where at least one housing wall (4) can be opened fully and/or in part and where at least one housing wall has a lock (6), and furthermore wherein the air regulation chamber (2) comprises the following components: a temperature-regulating unit (7), an air humidification unit (8) and a gas absorption unit (9). Furthermore, the invention relates to a labeling method for plants in which the labeling chamber according to the invention is employed.Type: GrantFiled: November 7, 2013Date of Patent: July 18, 2017Assignee: BASF PLANT SCIENCE COMPANY GMBHInventors: Regine Fuchs, Olaf Woiwode, Enrico Peter, Hardy Schön, Christoph Wittmann, Detlev Rasch, Veronique Beckers, Lisa Dersch
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Patent number: 9644220Abstract: Recombinant microorganisms with deregulated succinyl-CoA synthetase activity, as well as the uses for producing lysine, ?-lysine, cadaverine or N-acetylcadaverine thereby are provided. Recombinant polypeptides comprising an amino acid sequence being at least 80% identical to SEQ ID NO: 51 or 53 are also provided. The method of producing fine chemicals using said recombinant microorganisms, in particular the method of producing lysine, or derivatives thereof, such as ?-lysine, cadaverine or N-acetylcadaverine is further provided.Type: GrantFiled: December 14, 2012Date of Patent: May 9, 2017Assignee: BASF SEInventors: Christoph Wittmann, Stefanie Kind, Judith Becker
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Publication number: 20160362696Abstract: The present invention relates to a modified microorganism having, compared to its wild-type, a reduced activity of the enzyme that is encoded by the wcaJ-gene. The present invention also relates to a method for producing an organic compound and to the use of a modified microorganism.Type: ApplicationFiled: February 6, 2015Publication date: December 15, 2016Inventors: Joanna Martyna Krawczyk, Stefan Haefner, Hartwig Schröder, Esther Dantas Costa, Oskar Zelder, Gregory Von Abendroth, Christoph Wittmann, René Stellmacher, Judith Becker
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Publication number: 20160348082Abstract: The present invention relates to a modified microorganism having, compared to its wild-type, a reduced activity of the enzyme that is encoded by the pykA-gene. The present invention also relates to a method for producing an organic compound and to the use of modified microorganisms.Type: ApplicationFiled: February 2, 2015Publication date: December 1, 2016Inventors: Joanna Martyna Krawczyk, Stefan Haefner, Hartwig Schröder, Esther Dantas Costa, Oakar Zelder, Gregory von Abendroth, Christoph Wittmann, René Stellmacher, Judith Becker, Anna Lange, Benjamin J. Lyons, Thomas J. Lyons, Eudes De Crecy, Ewa Hughes
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Publication number: 20150309038Abstract: The present invention relates to an isotope labeling chamber for labeling metabolites in an organism, comprising a reactor chamber (1) and an air regulation chamber (2), wherein the reactor chamber (1) comprises the following components: optionally, a housing frame (3), housing walls (4), at least one injection valve (5), where at least one housing wall (4) can be opened fully and/or in part and where at least one housing wall has a lock (6), and furthermore wherein the air regulation chamber (2) comprises the following components: a temperature-regulating unit (7), an air humidification unit (8) and a gas absorption unit (9). Furthermore, the invention relates to a labeling method for plants in which the labeling chamber according to the invention is employed.Type: ApplicationFiled: November 7, 2013Publication date: October 29, 2015Inventors: Regine Fuchs, Olaf Woiwode, Enrico Peter, Hardy Schön, Christoph Wittmann, Detlev Rasch, Veronique Beckers, Lisa Dersch
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Patent number: 9169502Abstract: The present invention is directed to a method utilizing a recombinant microorganism for the production of aspartate derived amino acids and precursors thereof, in particular for the production of L-lysine. Furthermore, the present invention relates to a recombinant microorganism having improved aspartate-derived amino acid synthesis activity in comparison to the initial microorganism and the use of such microorganisms in producing said amino acids and precursors and derivatives, in particular in the synthesis of L-lysine.Type: GrantFiled: June 15, 2010Date of Patent: October 27, 2015Assignee: Paik Kwang Industrial Co., Ltd.Inventors: Christoph Wittmann, Judith Becker
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Publication number: 20150300419Abstract: The present invention relates to a clutch device having a counter-pressure plate and a contact plate which is movable to a limited extent in an axial direction of the clutch device by at least one lever element to clamp a clutch plate frictionally between the counter-pressure plate and the contact plate, wherein the counter-pressure plate has at least one strap segment extending essentially in an axial direction, to which a cover component is connected.Type: ApplicationFiled: October 14, 2013Publication date: October 22, 2015Applicant: SCHAEFFLER TECHNOLOGIES AG & CO. KGInventors: Igor Loran, Christoph Raber, Christoph Wittmann