Patents by Inventor Christophe D. Reymond

Christophe D. Reymond has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 6573059
    Abstract: The invention relates to the use of the regulatory subunit (R) of the cAMP dependent protein kinase (PKA) from Dictyostelium discoideum for cAMP detection. It includes constructs for expression of the R-subunit in E. coli and fusion to green fluorescent proteins (GFP). Fluorescence energy transfer is used as a way to monitor cAMP binding, either by using fluorescently labelled cAMP or cGMP, or by using mutant GFPs with modified absorption and emission spectra. FRET changes upon cAMP binding will allow measurement of cAMP level either in vitro or within living cells.
    Type: Grant
    Filed: June 2, 2000
    Date of Patent: June 3, 2003
    Assignee: RMF Dictagene S.A.
    Inventor: Christophe D. Reymond
  • Publication number: 20020110890
    Abstract: The invention relates to the use of the regulatory subunit (R) of the CAMP dependent protein kinase (PKA) from Dictyostelium discoideum for cAMP detection. It includes constructs for expression of the R-subunit in E. coli and fusion to green fluorescent proteins (GFP). Fluorescence energy transfer is used as a way to monitor cAMP binding, either by using fluorescently labelled cAMP or cGMP, or by using mutant GFPs with modified absorption and emission spectra. FRET changes upon cAMP binding will allow measurement of cAMP level either in vitro or within living cells.
    Type: Application
    Filed: April 11, 2002
    Publication date: August 15, 2002
    Applicant: RMF Dictagene S.A.
    Inventor: Christophe D. Reymond