Patents by Inventor Christophe GUIGNABERT

Christophe GUIGNABERT has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Pyrimidinone derivatives and uses thereof to neutralize the biological activity of chemokines
    Patent number: 11046657
    Abstract: A subject of the present invention is a compound having the general formula (I): a pharmaceutically acceptable salt thereof or a tautomeric form thereof, wherein A, B3, B4, B5, Y, X, B1 and B2 are as defined in any one of claims 1 to 10. Another subject of the invention is the compound as defined above for use as a medicament, in particular for preventing and/or treating inflammation and inflammatory diseases, immune and auto-immune diseases, pain related diseases, genetic diseases and/or cancer.
    Type: Grant
    Filed: July 13, 2017
    Date of Patent: June 29, 2021
    Assignees: Centre National de la Recherche Scientifique, Institut National de la Sante et de la Recherche Medicale, Universite de Strasbourg, Universite Paris-Sud, Centre International de Recherche aux Frontieres de la Chimie
    Inventors: Dominique Bonnet, Nelly Frossard, Jean-Luc Galzi, Christophe Guignabert, Marcel Hibert, Frédéric Simonin, Sylviane Muller
  • Pyrimidinone Derivatives and Uses Thereof to Neutralize the Biological Activity of Chemokines
    Publication number: 20200181093
    Abstract: A subject of the present invention is a compound having the general formula (I): a pharmaceutically acceptable salt thereof or a tautomeric form thereof, wherein A, B3, B4, B5, Y, X, B1 and B2 are as defined in any one of claims 1 to 10. Another subject of the invention is the compound as defined above for use as a medicament, in particular for preventing and/or treating inflammation and inflammatory diseases, immune and auto-immune diseases, pain related diseases, genetic diseases and/or cancer.
    Type: Application
    Filed: July 13, 2017
    Publication date: June 11, 2020
    Applicants: Centre National de la Recherche Scientifique (CNRS, Institut National de la Santé et de la Recherche Médicale (INSERM), Université de Strasbourg, Universite Paris-Sud, Centre International de Recherche aux Frontieres d e la Chimie
    Inventors: Dominique Bonnet, Nelly Frossard, Jean-Luc Galzi, Christophe Guignabert, Marcel Hibert, Frédéric Simonin, Sylviane Muller
  • MIF inhibitors for the acute or chronic treatment of pulmonary hypertension
    Patent number: 10071080
    Abstract: The present invention relates to the use of compounds of general Formula I and pharmaceutically acceptable enantiomers, salts or solvates thereof, for treating pulmonary hypertension in a subject.
    Type: Grant
    Filed: May 18, 2015
    Date of Patent: September 11, 2018
    Assignees: MIFCARE, INSERM (INSTITUT NATIONAL DE LA SANTÉ ET DE LA RECHERCHE MÉDICALE), UNIVERSITÉ PARIS-SUD 11
    Inventors: Gaël Jalce, Christophe Guignabert, Morane Le Hiress, Ly Tu, Bernardin Akagah
  • MIF INHIBITORS FOR THE ACUTE OR CHRONIC TREATMENT OF PULMONARY HYPERTENSION
    Publication number: 20170079958
    Abstract: The present invention relates to the use of compounds of general Formula I and pharmaceutically acceptable enantiomers, salts or solvates thereof, for treating pulmonary hypertension in a subject.
    Type: Application
    Filed: May 18, 2015
    Publication date: March 23, 2017
    Inventors: Gaël JALCE, Christophe GUIGNABERT, Morane LE HIRESS, Ly TU, Bernardin AKAGAH