Patents by Inventor Christophe Guillaume Malan

Christophe Guillaume Malan has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Process for the preparation of enantiomerically enriched n-acyl-beta-amino acid derivatives by enantioselective hydrogenation of the corresponding (z)-enamides
    Publication number: 20040186314
    Abstract: A process for the preparation of an enantiomerically enriched beta-amino acid derivative of formula (1), or the opposite enantiomer thereof, wherein R1 is an optionally substituted alkyl, aryl or heteroaryl group of up to 20 C atoms, R2 is ann alkyl group of up to 20 C atoms, and R3 is H or an alkyl or aryl group of up to 20 C atoms, which comprises asymmetric hydrogenation of the (z)-enamide precursor (2) in an alcohol solvent or cosolvent, catalysed by a cationic rhodium complex of a chiral phosphine ligand having the partial formula (3), wherein n is 0 to 6 and R represents at least one non-hydrogen organic group of up to 20 C atoms.
    Type: Application
    Filed: January 28, 2004
    Publication date: September 23, 2004
    Inventors: Christophe Guillaume Malan, Christopher Cobley
  • Phosphorus p-cyclophane ligands and their use in transition metal catalyzed asymmetric reactions
    Patent number: 6613922
    Abstract: Chiral di-phosphonites and phosphhours diamides based on the ps-ortho disubstituted p-cyclophane skeleton are good ligands for transition metals, notably rhodium, iridium and ruthenium. Preferably, the transition metals are linked to the ligands by a diene compound chosen from 2,5-Norbornadiene (NBD) and 1,5-Cyclooctadiene (COD).
    Type: Grant
    Filed: January 22, 2002
    Date of Patent: September 2, 2003
    Assignee: Chirotech Technology Limited
    Inventors: Antonio Zanotti-Gerosa, Christophe Guillaume Malan, Julian Henschke, Daniela Herzberg
  • Chiral ligands for asymmetric catalysis
    Patent number: 6508753
    Abstract: A novel phosphine ligand is an enantiomerically enriched compound of formula 5 or the opposite enantiomer thereof, wherein Ar1 and Ar2 represent the same or different aromatic groups of up to 20 C atoms. A transition metal complex of this ligand is useful as a catalyst in stereoselective hydrogenation.
    Type: Grant
    Filed: June 4, 2001
    Date of Patent: January 21, 2003
    Assignee: Chirotech Technology Limited
    Inventors: Mark Joseph Burk, Christophe Guillaume Malan
  • Ligands and their use
    Publication number: 20020151735
    Abstract: A compound of the following formula: 1
    Type: Application
    Filed: January 22, 2002
    Publication date: October 17, 2002
    Inventors: Antonio Zanotti-Gerosa, Christophe Guillaume Malan, Julian Henschke, Daniela Herzberg
  • Chiral ligands for asymmetric catalysis
    Publication number: 20020035285
    Abstract: A novel phosphine ligand is an enantiomerically enriched compound of formula 5 1
    Type: Application
    Filed: June 4, 2001
    Publication date: March 21, 2002
    Inventors: Mark Joseph Burk, Christophe Guillaume Malan