Abstract: A turbomachine module with a longitudinal axis comprising an unducted propeller rotated about the longitudinal axis and at least one straightener. The module includes a plurality of unducted variable-pitch stator blades extending along a radial axis, perpendicular to the longitudinal axis, from a fixed casing. The module includes a first stator blade pitch-changing system. The pitch-changing system includes at least one first control that includes a first fixed body connected to the fixed casing and a first body which is axially mobile in relation to the first fixed body and at least one first joining mechanism joining each stator blade to the first mobile body of the first control. The first joining mechanism includes: a joining ring centered on the longitudinal axis, joined to the feet of each stator blade and at least one lever joined, on one hand, to the joining ring and, on the other hand, to the first mobile body of the first control.

Abstract: A turbomachine module with a longitudinal axis comprising an unducted propeller rotated about the longitudinal axis and at least one straightener. The module includes a plurality of unducted variable-pitch stator blades extending along a radial axis, perpendicular to the longitudinal axis, from a fixed casing. The module includes a first stator blade pitch-changing system. The pitch-changing system includes at least one first control that includes a first fixed body connected to the fixed casing and a first body which is axially mobile in relation to the first fixed body and at least one first joining mechanism joining each stator blade to the first mobile body of the first control. The first joining mechanism includes: a joining ring centered on the longitudinal axis, joined to the feet of each stator blade and at least one lever joined, on one hand, to the joining ring and, on the other hand, to the first mobile body of the first control.

Abstract: A system for the axial retention of a holding ring for a bearing for guiding in rotation a rotary shaft of a turbomachine is disclosed. The system includes an annular bearing support and a bearing holding ring that is borne by the annular bearing support. The bearing holder ring includes an upstream ring configured to be brought into contact with the bearing support and a downstream ring that is elastically deformable. The bearing support has a first axial retention element, and the bearing holding ring has a second axial retention element. The first and second axial retention elements are configured to cooperate with one another to axially retain the bearing holding ring in the event of damage to the downstream ring.

Abstract: A system for the axial retention of a holding ring for a bearing for guiding in rotation a rotary shaft of a turbomachine is disclosed. The system includes an annular bearing support and a bearing holding ring that is borne by the annular bearing support. The bearing holder ring includes an upstream ring configured to be brought into contact with the bearing support and a downstream ring that is elastically deformable. The bearing support has a first axial retention element, and the bearing holding ring has a second axial retention element. The first and second axial retention elements are configured to cooperate with one another to axially retain the bearing holding ring in the event of damage to the downstream ring.

Abstract: A turbomachine bearing housing comprising a fixed wall, a rotating shaft, first and second seals between the wall and the shaft, and a chamber between the fixed wall and a stator element supplied with air via an opening close to the shaft. An air guide is arranged along the surface of the wall of the housing, outside same, such that at least a portion of the air exiting the guide passes between the first seal and the shaft, the air guide being supplied with air by an air intake separated radially from the shaft, the air from the air intake being at a higher pressure than at the shaft.

Abstract: A turbomachine bearing housing comprising a fixed wall, a rotating shaft, first and second seals between the wall and the shaft, and a chamber between the fixed wall and a stator element supplied with air via an opening close to said shaft. An air guide means is arranged along the surface of the wall of the housing, outside same, such that at least a portion of the air exiting the guide means passes between the first seal and the shaft, said guide means being supplied with air by an air intake separated radially from the shaft, the air from the air intake being at a higher pressure than at the shaft.

Abstract: The present invention relates to methods of preventing and treating tuberculosis in a subject infected with Mycobacterium tuberculosis. The method involves inhibiting AhpD in the subject under conditions effective to make the pathogen susceptible to antimicrobial reactive nitrogen intermediates or reactive oxygen intermediates. The present invention also relates to methods of preventing and treating tuberculosis in a subject infected with Mycobacterium tuberculosis involving inhibiting dihydrolipoamide dehydrogenase or dihydrolipoamide succinyltransferase in Mycobacterium tuberculosis in the subject under conditions effective to make the pathogen susceptible to antimicrobial reactive nitrogen intermediates or reactive oxygen intermediates. Also disclosed are methods for identifying candidate compounds suitable for treatment or prevention of tuberculosis.

Abstract: A recombinant expression system for the expression of a poly amino acid, peptide or protein is provided. The poly amino acid of interest is expressed as a fusion protein that includes an amino acid sequence recognized and cleaved by a Ulp1 protease. The amino acid sequence joined to the poly amino acid of interest is preferably from a SUMO (small ubiquitin-like molecule) protein. This sequence imparts favorable solubility and refolding properties to the fusion protein. A purification tag may also be incorporated into the fusion protein for ease of isolation. The Ulp1 protease used to cleave the fusion protein may be the Ulp1 protease or the active Ulp1 protease fragment, Ulp1(403-621). The Ulp1 protease rapidly and specifically cleaves the fusion proteins of the invention at the Ulp1 cleavage site. The amino acid sequence recognized by a Ulp1 protease is cleaved asymetrically to leave only an N-terminal serine joined to the poly amino acid of interest.