Patents by Inventor Christophe Michoud

Christophe Michoud has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Tetrahydro-benzodiazepinones
    Patent number: 10053431
    Abstract: Disclosed are compounds of Formula I, or pharmaceutically acceptable salts thereof, wherein W, X, Y, Z, R1, R2, R3, R4 and R5 are as described in this application, and methods of using said compounds in the treatment of cancer.
    Type: Grant
    Filed: November 14, 2014
    Date of Patent: August 21, 2018
    Assignee: Hoffmann-La Roche Inc.
    Inventors: Shaoqing Chen, Andrew F. Donnell, Robert Francis Kester, Kang Le, Yan Lou, Christophe Michoud, Stacy Remiszewski, Kenneth C. Rupert, Martin Weisel
  • Antiproliferative benzo [B] azepin-2-ones
    Patent number: 9611224
    Abstract: Disclosed are compounds of Formula (I) or pharmaceutically acceptable salts thereof, wherein W, X, Y, Z, R1, R2, R3 and R4 are described in this application, and methods of using said compounds in the treatment of cancer.
    Type: Grant
    Filed: July 11, 2013
    Date of Patent: April 4, 2017
    Assignee: HOFFMANN-LA ROCHE INC.
    Inventors: Xiaochun Han, Yan Lou, Christophe Michoud, Steven Gregory Mischke, Stacy Remiszewski, Kenneth Carey Rupert
  • TETRAHYDRO-BENZODIAZEPINONES
    Publication number: 20160272596
    Abstract: Disclosed are compounds of Formula I, or pharmaceutically acceptable salts thereof, wherein W, X, Y, Z, R1, R2, R3, R4 and R5 are as described in this application, and methods of using said compounds in the treatment of cancer.
    Type: Application
    Filed: November 14, 2014
    Publication date: September 22, 2016
    Inventors: Shaoqing Chen, Andrew F. Donnell, Robert Francis Kester, Kang Le, Yan Lou, Christophe Michoud, Stacy Remiszewski, Kenneth C. Rupert, Martin Weisel
  • Substituted hetero-azepinones
    Patent number: 9394263
    Abstract: There are provided compounds of the formula wherein: V, W, X, Y, Z, R1, R2, R3, R4, R5 and R6 are described herein. The compounds are useful for the treatment of proliferative diseases, including cancer.
    Type: Grant
    Filed: August 6, 2013
    Date of Patent: July 19, 2016
    Assignee: F. HOFFMANN-LA ROCHE AG
    Inventors: Andrew F. Donnell, Xiaochun Han, Robert Francis Kester, Norman Kong, Kang Le, Yan Lou, Christophe Michoud, John Anthony Moliterni, Stacy Remiszewski, Kenneth Carey Rupert, Weiya Yun
  • SUBSTITUTED HETERO-AZEPINONES
    Publication number: 20150361059
    Abstract: There are provided compounds of the formula wherein: V, W, X, Y, Z, R1, R2, R3, R4, R5 and R6 are described herein. The compounds are useful for the treatment of proliferative diseases, including cancer.
    Type: Application
    Filed: August 6, 2013
    Publication date: December 17, 2015
    Applicant: Hoffman-La Roche Inc.
    Inventors: Andrew F. Donnell, Xiaochun Han, Robert Francis Kester, Norman Kong, Kang Le, Yan Lou, Christophe Michoud, John Anthony Moliterni, Stacy Remiszewski, Kenneth Carey Rupert, Weiya Yun
  • ANTIPROLIFERATIVE BENZO [B] AZEPIN-2-ONES
    Publication number: 20150353499
    Abstract: Disclosed are compounds of Formula (I) or pharmaceutically acceptable salts thereof, wherein W, X, Y, Z, R1, R2, R3 and R4 are described in this application, and methods of using said compounds in the treatment of cancer.
    Type: Application
    Filed: July 11, 2013
    Publication date: December 10, 2015
    Applicant: Hoffman-La Roche Inc.
    Inventors: Xiaochun Han, Yan Lou, Christophe Michoud, Steven Gregory Mischke, Stacy Remiszewski, Kenneth Carey Rupert
  • Benzotriazole kinase modulators
    Patent number: 8962622
    Abstract: Compounds of formula I modulate jnk and cdk: or a pharmaceutically acceptable salt thereof, where R, R1, R2, R3, and m are defined herein.
    Type: Grant
    Filed: September 7, 2007
    Date of Patent: February 24, 2015
    Assignee: Roche Palo Alto LLC
    Inventors: David Michael Goldstein, Levi Gong, Christophe Michoud, Wylie Solang Palmer, Achyutharao Sidduri
  • Thiazole and thiophene compounds
    Patent number: 8404859
    Abstract: Provided herein are compounds of the formula (I): as well as pharmaceutically acceptable salts thereof, wherein the substituents are as those disclosed in the specification. These compounds, and the pharmaceutical compositions containing them, are useful for the treatment of inflammatory diseases and disorders such as, for example, asthma and COPD.
    Type: Grant
    Filed: February 17, 2012
    Date of Patent: March 26, 2013
    Assignee: Hoffmann-La Roche Inc.
    Inventors: Paul Gillespie, Christophe Michoud, Kenneth Carey Rupert, Kshitij Chhabilbhai Thakkar
  • JNK modulators
    Patent number: 8399462
    Abstract: Compounds of formula I modulate JNK: wherein the variables are as defined herein.
    Type: Grant
    Filed: December 7, 2007
    Date of Patent: March 19, 2013
    Assignee: Roche Palo Alto LLC
    Inventors: James Patrick Dunn, Leyi Gong, David Michael Goldstein, Xiaochun Han, Joan Heather Hogg, Wylie Solang Palmer, Lubica Raptova, Tania Silva, Parcharee Tivitmahaisoon, Teresa Alejandra Trejo-Martin, Christophe Michoud, Achyutharao Sidduri
  • PYRIMIDINE AMIDE COMPOUNDS
    Publication number: 20120270875
    Abstract: Provided herein are compounds of the formula (I): as well as pharmaceutically acceptable salts thereof, wherein the substituents are as those disclosed in the specification. These compounds, and the pharmaceutical compositions containing them, are useful for the treatment of inflammatory diseases and disorders such as, for example, asthma and COPD.
    Type: Application
    Filed: February 17, 2012
    Publication date: October 25, 2012
    Inventors: Paul Gillespie, Christophe Michoud, Kenneth Carey Rupert, Kshitij Chhabilbhai Thakkar, Lin Yi
  • THIAZOLE AND THIOPHENE COMPOUNDS
    Publication number: 20120238569
    Abstract: Provided herein are compounds of the formula (I): as well as pharmaceutically acceptable salts thereof, wherein the substituents are as those disclosed in the specification. These compounds, and the pharmaceutical compositions containing them, are useful for the treatment of inflammatory diseases and disorders such as, for example, asthma and COPD.
    Type: Application
    Filed: February 17, 2012
    Publication date: September 20, 2012
    Inventors: Paul Gillespie, Christophe Michoud, Kenneth Carey Rupert, Kshitij Chhabilbhai Thakkar
  • Thiazolyl-benzimidazoles
    Patent number: 7504513
    Abstract: The invention is directed to compounds of formula (1) and pharmaceutically acceptable salts thereof, methods for the preparation thereof, and methods of use thereof.
    Type: Grant
    Filed: February 7, 2007
    Date of Patent: March 17, 2009
    Assignee: Hoffman-La Roche Inc.
    Inventors: John Frederick Boylan, Jianping Cai, Nader Fotouhi, Paul Gillespie, Robert Alan Goodnow, Jr., Kang Le, Christophe Michoud
  • Diacylglycerol acyltransferase inhibitors
    Patent number: 7485752
    Abstract: Provided herein are compounds of the formula (I): as well as pharmaceutically acceptable salts thereof, wherein the substituents are as those disclosed in the specification. These compounds, and the pharmaceutical compositions containing them, are useful for the treatment of diseases such as, for example, obesity, type II diabetes mellitus and metabolic syndrome.
    Type: Grant
    Filed: May 5, 2006
    Date of Patent: February 3, 2009
    Assignee: Hoffman-La Roche Inc.
    Inventor: Christophe Michoud
  • JNK modulators
    Publication number: 20080146565
    Abstract: Compounds of formula I modulate JNK: wherein the variables are as defined herein.
    Type: Application
    Filed: December 7, 2007
    Publication date: June 19, 2008
    Inventors: James Patrick Dunn, Leyi Gong, David Michael Goldstein, Xiaochun Han, Joan Heather Hogg, Wylie Solang Palmer, Lubica Raptova, Tania Silva, Parcharee Tivitmahaisoon, Teresa Alejandra Trejo-Martin, Christophe Michoud, Achyutharao Sidduri
  • Benzotriazole kinase modulators
    Publication number: 20080103142
    Abstract: Compounds of formula I modulate jnk and cdk: or a pharmaceutically acceptable salt thereof, where R, R1, R2, R3, and m are defined herein.
    Type: Application
    Filed: September 7, 2007
    Publication date: May 1, 2008
    Inventors: David Goldstein, Leyi Gong, Christophe Michoud, Wylie Palmer, Achyutharao Sidduri
  • Diacylglycerol acyltransferase inhibitors
    Patent number: 7317125
    Abstract: Provided herein are compounds of the formula (I): as well as pharmaceutically acceptable salts thereof, wherein the substituents are as those disclosed in the specification. These compounds, and the pharmaceutical compositions containing them, are useful for the treatment of diseases such as, for example, obesity, type II diabetes mellitus and metabolic syndrome.
    Type: Grant
    Filed: January 31, 2006
    Date of Patent: January 8, 2008
    Assignee: Hoffman-La Roche Inc.
    Inventors: David Robert Bolin, Christophe Michoud
  • Thiazolyl-benzimidazoles
    Publication number: 20070203210
    Abstract: The invention is directed to compounds of formula (1) and pharmaceutically acceptable salts thereof, methods for the preparation thereof, and methods of use thereof.
    Type: Application
    Filed: February 7, 2007
    Publication date: August 30, 2007
    Inventors: John Frederick Boylan, Jianping Cai, Nader Fotouhi, Paul Gillespie, Robert Alan Goodnow, Kang Le, Christophe Michoud
  • Thiazolinone 3,4-disubstituted quinolines
    Patent number: 7250515
    Abstract: Thiazolinone disubstituted quinoline derivatives where the quinoline ring is disubstituted at the 3, 4 positions which derivatives demonstrate CDK1 antiproliferative activity and are useful as anti-cancer agents.
    Type: Grant
    Filed: June 29, 2005
    Date of Patent: July 31, 2007
    Assignee: Hoffman-La Roche Inc.
    Inventors: Li Chen, Shaoqing Chen, Christophe Michoud
  • Thiazolinone 2-substituted quinolines
    Patent number: 7241893
    Abstract: Thiazolinone substituted quinoline derivatives where the quinoline ring is substituted at the 2 position which derivatives demonstrates CDK1 antiproliferative activity and are useful as anti-cancer agents.
    Type: Grant
    Filed: September 12, 2005
    Date of Patent: July 10, 2007
    Assignee: Hoffman-La Roche Inc.
    Inventors: Li Chen, Shaoqing Chen, Christophe Michoud
  • Diacylglycerol acyltransferase inhibitors
    Publication number: 20060258740
    Abstract: Provided herein are compounds of the formula (I): as well as pharmaceutically acceptable salts thereof, wherein the substituents are as those disclosed in the specification. These compounds, and the pharmaceutical compositions containing them, are useful for the treatment of diseases such as, for example, obesity, type II diabetes mellitus and metabolic syndrome.
    Type: Application
    Filed: May 5, 2006
    Publication date: November 16, 2006
    Inventor: Christophe Michoud