Patents by Inventor Christophe Philippo

Christophe Philippo has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Thiadiazole and oxadiazole derivatives, preparation thereof and therapeutic use thereof
    Patent number: 8546391
    Abstract: The invention relates to compounds of the formula (I) either (i) in the state of a base or an acid addition salt, or (ii) in the state of an acid or a base addition salt, as well as to a method for preparing same and to the therapeutic applications thereof.
    Type: Grant
    Filed: January 27, 2010
    Date of Patent: October 1, 2013
    Assignee: Sanofi
    Inventors: Eykmar Fett, Patrick Mougenot, Claudie Namane, Eric Nicolai, Christophe Philippo
  • Substituted adamantanes and their therapeutic application
    Patent number: 8530657
    Abstract: The present invention relates to tetrahydroquinoxaline urea derivatives of formula (I) as defined herein, and, to their preparation and to their therapeutic application.
    Type: Grant
    Filed: May 30, 2012
    Date of Patent: September 10, 2013
    Assignee: Sanofi
    Inventors: Alain Jean Braun, Olivier Crespin, Claudie Namane, Eric Nicolai, Francois Pacquet, Cecile Pascal, Christophe Philippo, Olivier Venier
  • TETRAHYDROQUINOXALINE UERA DERIVATIVES, THEIR PREPARATION AND THEIR THERAPEUTIC APPLICATION
    Publication number: 20120245148
    Abstract: The present invention relates to tetrahydroquinoxaline urea derivatives, to their preparation and to their therapeutic application.
    Type: Application
    Filed: May 30, 2012
    Publication date: September 27, 2012
    Applicant: SANOFI
    Inventors: Alain Jean Braun, Olivier Crespin, Claudie Namane, Eric Nicolai, Francois Pacquet, Cecile Pascal, Christophe Philippo, Olivier Venier
  • Tetrahydroquinoxaline urea derivatives
    Patent number: 8211892
    Abstract: The present invention relates to tetrahydroquinoxaline urea derivatives of Formula (I): as disclosed herein, to their preparation and to their therapeutic application.
    Type: Grant
    Filed: July 26, 2010
    Date of Patent: July 3, 2012
    Assignee: Sanofi-Aventis
    Inventors: Alain Jean Braun, Olivier Crespin, Claudie Namane, Eric Nicolai, Francois Pacquet, Cecile Pascal, Christophe Philippo, Olivier Venier
  • THIADIAZOLE AND OXADIAZOLE DERIVATIVES, PREPARATION THEREOF AND THERAPEUTIC USE THEREOF
    Publication number: 20120040984
    Abstract: The invention relates to compounds of the formula (I) either (i) in the state of a base or an acid addition salt, or (ii) in the state of an acid or a base addition salt, as well as to a method for preparing same and to the therapeutic applications thereof.
    Type: Application
    Filed: January 27, 2010
    Publication date: February 16, 2012
    Applicant: SANOFI
    Inventors: Eykmar Fett, Patrick Mougenot, Claudie Namane, Eric Nicolai, Christophe Philippo
  • Substituted quinoxalines, their preparation and their therapeutical use as 11?HSD1 modulators
    Patent number: 7947834
    Abstract: The present invention is related to a compound of formula (I): wherein i, j, n, o, p, q, r, R1a, R1b, R1c, R1d, R2a, R2b, R2c, R2d, R3a, R3b and R4 are as defined herein, or an addition salt with an acid thereof, or a hydrate or solvate thereof, its preparation, pharmaceutical composition, and uses for treating a disease in which the enzyme 11?-HSD1 is involved.
    Type: Grant
    Filed: December 18, 2008
    Date of Patent: May 24, 2011
    Assignee: Sanofi-Aventis
    Inventors: Alain Braun, Patrick Mougenot, Claudie Namane, Eric Nicolai, Francois Pacquet, Christophe Philippo, Olivier Venier, Olivier Crespin, Cecile Pascal, Michel Aletru, Stefan Gussregen
  • PYRAZOLE DERIVATIVES AND USE THEREOF AS OREXIN RECEPTOR ANTAGONISTS
    Publication number: 20110059964
    Abstract: The present invention relates to the orexin receptor antagonists compounds of the general formula (I) as well as to their isomers, salts and solvates, to the pharmaceutical compositions containing them and to the therapeutic application thereof.
    Type: Application
    Filed: February 3, 2010
    Publication date: March 10, 2011
    Applicant: sanofi-aventis
    Inventors: Michel Aletru, Peter Aranyi, Maria Balogh, Sandor Batori, Judit Bence, Philippe Bovy, Zoltan Kapui, Endre Mikus, Claudie Namane, Christophe Philippo, Tibor Szabo, Zsuzsanna Tomoskozi, Katalin Urban-Szabo
  • Urea derivatives of tropane, their preparation and their therapeutic application
    Patent number: 7897773
    Abstract: The present invention is related to a compound of formula (I) wherein R1a, R1b, R1c, R1d, R2a, R2b, R3, R4, p, r and are as defined herein, its preparation, pharmaceutical composition and use as a modulator of the activity of the 11?-hydroxysteroid dehydrogenase type 1 (11?HSD1).
    Type: Grant
    Filed: December 11, 2008
    Date of Patent: March 1, 2011
    Assignee: Sanofi-Aventis
    Inventors: Michel Aletru, Alain Jean Braun, Claudie Namane, Olivier Venier, Christophe Philippo, Patrick Mougenot, Eric Nicolai, Stefan Gussregen
  • TETRAHYDROQUINOXALINE UREA DERIVATIVES, THEIR PREPARATION AND THEIR THERAPEUTIC APPLICATION
    Publication number: 20110009391
    Abstract: The present invention relates to tetrahydroquinoxaline urea derivatives, to their preparation and to their therapeutic application.
    Type: Application
    Filed: July 26, 2010
    Publication date: January 13, 2011
    Applicant: SANOFI-AVENTIS
    Inventors: Alain Jean BRAUN, Olivier CRESPIN, Claudie NAMANE, Eric NICOLAI, Francois PACQUET, Cecile PASCAL, Christophe PHILIPPO, Olivier VENIER
  • UREA DERIVATIVES OF TROPANE, THEIR PREPARATION AND THEIR THERAPEUTIC APPLICATION
    Publication number: 20100324084
    Abstract: The present invention is related to a compound of formula (I) wherein R1a, R1b, R1c, R1d, R2a, R2b, R3, R4, p, r and are as defined herein, its preparation, pharmaceutical composition and use as a modulator of the activity of the 11?-hydroxysteroid dehydrogenase type 1 (11?HSD1).
    Type: Application
    Filed: August 30, 2010
    Publication date: December 23, 2010
    Applicant: SANOFI-AVENTIS
    Inventors: Michel ALETRU, Alain Jean BRAUN, Claudie NAMANE, Olivier VENIER, Christophe PHILIPPO, Patrick MOUGENOT, Eric NICOLAI, Stefan GUSSREGEN
  • NOVEL SUBSTITUTED INDAZOLES, THE PREPARATION THEREOF AND USE OF SAME IN THERAPEUTICS
    Publication number: 20100298377
    Abstract: This disclosure relates to compounds of formula (I): wherein R1, R2, R3, R4, E, and n1 are as defined in the disclosure, to compositions containing them, to processes for preparing them, and the use thereof.
    Type: Application
    Filed: December 11, 2009
    Publication date: November 25, 2010
    Applicant: SANOFI-AVENTIS
    Inventors: Michel ALETRU, Dominique DAMOUR, Patrick MOUGENOT, Frederico NARDI, Patrick NEMECEK, Christophe PHILIPPO, Catherine MONSEAU, Claudie NAMANE
  • Pyrimidine derivatives as orexin receptor antagonists
    Patent number: 7812031
    Abstract: The present invention relates to substituted pyrimidine compounds of formula I useful as orexin receptor antagonists. The invention also relates to pharmaceutical compositions containing said compounds.
    Type: Grant
    Filed: August 10, 2006
    Date of Patent: October 12, 2010
    Assignee: Sanofi-Aventis
    Inventors: Peter Aranyi, Maria Balogh, Sandor Batori, Judit Bence, Michel Finet, Zoltan Kapui, Christophe Philippo, Tibor Szabo, Zoltan Szlavik, Zsuzsanna Tomoskozi, Katalin Urban-Szabo, Olivier Venier
  • AZOLOARINE DERIVATIVES, METHOD FOR THE PRODUCTION THEREOF, PHARMACEUTICALS CONTAINING THESE COMPOUNDS AND THE USE THEREOF
    Publication number: 20100240580
    Abstract: The invention relates to azoloarine derivatives of formula I wherein R, A, B, D, Y, X, M and W are as defined herein, and their physiologically tolerated salts.
    Type: Application
    Filed: February 18, 2010
    Publication date: September 23, 2010
    Applicant: SANOFI-AVENTIS
    Inventors: Gerhard ZOLLER, Marc Dietrich VOSS, Hans MATTER, Andreas HERLING, Christophe Philippo, Claudie NAMANE, Juan-Antonio SANCHEZ-ARIAS
  • Pyrazole derivatives and use thereof as orexin receptor antagonists
    Patent number: 7659298
    Abstract: The present invention relates to the orexin receptor antagonists compounds of the general formula (I) as well as to their isomers, salts and solvates, to the pharmaceutical compositions containing them and to the therapeutic application thereof.
    Type: Grant
    Filed: June 21, 2006
    Date of Patent: February 9, 2010
    Assignee: sanofi-aventis
    Inventors: Michel Aletru, Peter Aranyi, Maria Balogh, Sandor Batori, Judit Bence, Philippe Bovy, Zoltan Kapui, Endre Mikus, Claudie Namane, Christophe Philippo, Tibor Szabo, Zsuzsanna Tomoskozi, Katalin Urban-Szabo
  • DERIVATIVES OF UREAS OF PIPERIDINE OR PYRROLIDINE, THEIR PREPARATION AND THEIR THERAPEUTICAL USE
    Publication number: 20090176775
    Abstract: The present invention is related to a compound of formula (I): wherein i, j, n, o, p, q, r, R1a, R1b, R1c, R1d, R2a, R2b, R2c, R2d, R3a, R3b and R4 are as defined herein, or an addition salt with an acid thereof, or a hydrate or solvate thereof, its preparation, pharmaceutical composition, and uses for treating a disease in which the enzyme 11?-HSD1 is involved.
    Type: Application
    Filed: December 18, 2008
    Publication date: July 9, 2009
    Applicant: SANOFI-AVENTIS
    Inventors: Alain BRAUN, Patrick MOUGENOT, Claudie NAMANE, Eric NICOLAI, Francois PACQUET, Christophe PHILIPPO, Olivier VENIER, Olivier CRESPIN, Cecile PASCAL, Michel ALETRU, Stefan GUSSREGEN
  • UREA DERIVATIVES OF TROPANE, THEIR PREPARATION AND THEIR THERAPEUTIC APPLICATION
    Publication number: 20090170894
    Abstract: The present invention is related to a compound of formula (I) wherein R1a, R1b, R1c, R1d, R2a, R2b, R3, R4, p, r and are as defined herein, its preparation, pharmaceutical composition and use as a modulator of the activity of the 11?-hydroxysteroid dehydrogenase type 1 (11?HSD1).
    Type: Application
    Filed: December 11, 2008
    Publication date: July 2, 2009
    Applicant: SANOFI-AVENTIS
    Inventors: Michel ALETRU, Alain Jean BRAUN, Claudie NAMANE, Olivier VENIER, Christophe PHILIPPO, Patrick MOUGENOT, Eric NICOLAI, Stefan GUSSREGEN
  • PYRIMIDINE DERIVATIVES AS OREXIN RECEPTOR ANTAGONISTS
    Publication number: 20070043037
    Abstract: The present invention relates to the orexin receptor antagonists of the general formula (I), which are selective to orexin I receptors.
    Type: Application
    Filed: August 10, 2006
    Publication date: February 22, 2007
    Applicant: SANOFI-AVENTIS
    Inventors: Peter ARANYI, Maria BALOGH, Sandor BATORI, Judit BENCE, Michel FINET, Zoltan KAPUI, Christophe PHILIPPO, Tibor SZABO, Zoltan SZLAVIK, Zsuzsanna TOMOSKOZI, Katalin URBAN-SZABO, Olivier VENIER
  • PYRAZOLE DERIVATIVES AND USE THEREOF AS OREXIN RECEPTOR ANTAGONISTS
    Publication number: 20070021459
    Abstract: The present invention relates to the orexin receptor antagonists compounds of the general formula (I) as well as to their isomers, salts and solvates, to the pharmaceutical compositions containing them and to the therapeutic application thereof.
    Type: Application
    Filed: June 21, 2006
    Publication date: January 25, 2007
    Applicant: SANOFI-AVENTIS
    Inventors: Michel ALETRU, Peter ARANYI, Maria BALOGH, Sandor BATORI, Judit BENCE, Philippe BOVY, Zoltan KAPUI, Endre MIKUS, Claudie NAMANE, Christophe PHILIPPO, Tibor SZABO, Zsuzsanna TOMOSKOZI, Katalin URBAN-SZABO
  • 2-arylquinoline derivatives, preparation and therapeutic use thereof
    Patent number: 6617336
    Abstract: Compounds of general formula (I) in which: A represents a hydrogen atom, a hydroxyl, a C1-3 alkoxy group, a hydroxy(C1-6 alkyl) group, a (C1-3 alkoxy)(C1-3 alkyl) group, a thiol, (C1-6 alkyl)sulfanyl or a halogen; B and D represent, independently of one another, a hydrogen atom, a C1-6 alkyl group, a fluoro(C1-6 alkyl) group or a perfluoro(C1-2 alkyl) group or B and D together from an oxo; R1 represents a phenyl, a naphthyl or a heteroaryl comprising 4 or 5 carbon atoms; R2 and R3 represent, independently of one another, a hydrogen atom, a halogen or a C1-6 alkyl group, R4 represents a hydrogen atom, a hydroxyl or a halogen, and R5 and R6 represent, independently of one another, a hydrogen atom, a C1-6 alkyl group, a C2-6 alkenyl group, a C3-6 cycloalkyl group, a C3-6 cycloalkenyl group, a fluoro(C1-6 alkyl) group or a perfluoro(C1-2 alkyl) group or R5 and R6 together form a C2-6 alkylene chain or a C3-6 alkenylene chain, to give, with the nitrogen to which they are attached, a heteroc
    Type: Grant
    Filed: May 22, 2002
    Date of Patent: September 9, 2003
    Assignee: Sanofi-Synthelabo
    Inventors: Philippe R Bovy, Alain Braun, Christophe Philippo
  • 2-Phenyl-quinoline derivatives, preparation method and therapeutic use thereof
    Publication number: 20030097000
    Abstract: Compounds of general formula (I) 1
    Type: Application
    Filed: June 14, 2002
    Publication date: May 22, 2003
    Inventors: Philippe R. Bovy, Alain Braun, Christophe Philippo