Patents by Inventor Christophe Piot

Christophe Piot has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Inhibitors of apoptosis and uses thereof
    Patent number: 9814758
    Abstract: The invention relates to fragments of the Death-Domain Associated protein (DAXX protein) and of the Fas-Associated Death Domain protein (FADD protein) that inhibit cell apoptosis, in particular cell apoptosis mediated by the Fas receptor. The invention also relates to derivatives of said anti-apoptotic fragments, conjugates comprising said fragments, pharmaceutical compositions comprising said fragments, and to the medical applications of said fragments, derivatives, conjugates, and pharmaceutical compositions thereof in the treatment or prevention of diseases and conditions associated with apoptosis.
    Type: Grant
    Filed: November 17, 2011
    Date of Patent: November 14, 2017
    Assignees: CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE-CNRS, UNIVERSITE MONTPELLIER 2-SCIENCES ET TECHNIQUE, UNIVERSITE DE MONTPELLIER 1
    Inventors: Stéphanie Barrere, Joël Nargeot, Bernard Lebleu, Prisca Boisguerin, Christophe Piot
  • Inhibitors of Apoptosis and Uses Thereof
    Publication number: 20130288979
    Abstract: The invention relates to fragments of the DAXX and FADD proteins that inhibit cell apoptosis, in particular cell apoptosis mediated by the Fas receptor. The invention also relates to derivatives of said anti-apoptotic fragments, conjugates comprising said fragments, pharmaceutical compositions comprising said fragments, and to the medical applications of said fragments, derivatives, conjugates, and pharmaceutical compositions thereof in the treatment or prevention of diseases and conditions associated with apoptosis.
    Type: Application
    Filed: November 17, 2011
    Publication date: October 31, 2013
    Applicants: CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE-CNRS, UNIVERSITE DE MONTPELLIER 1, UNIVERSITE MONTPELLIER 2-SCIENCES ET TECHNIQUE
    Inventors: Stéphanie Barrere, Joël Nargeot, Bernard Lebleu, Prisca Boisguerin, Christophe Piot
  • Bacillus thuringiensis transformation method
    Patent number: 5858745
    Abstract: Particularly effective B.t. insecticides are obtained by culturing to the sporulation stage novel transformant obtained on transforming B.t. kurstaki H.D. 562 with DNA expressing in the B.t. certain mutant endotoxin genes. Such transformants and other B.t. transformants generally may be obtained in high transformation frequencies by the electrotransformation of B.t. cells while in a hypertonic state followed by maintaining the cells in a hypertonic medium for a time sufficient to obtain intact cells. Transformation of B.t. tenebroinis and B.t. aizawai is also described.
    Type: Grant
    Filed: October 24, 1997
    Date of Patent: January 12, 1999
    Assignee: Novartis Finance Corporation
    Inventors: Cindy Lou Jellis, Noah D. Beerman, Jean-Christophe Piot
  • Insecticidal hybrid bacteria from b.t. kurstaki and b.t. tenebrionis
    Patent number: 4797279
    Abstract: The invention provides hybrid microorganisms comprising the gene coding for b.t. kurstaki delta-endotoxin and the gene coding for b.t. tenebrionis delta-endotoxin, their preparation, insecticidal compositions comprising such microorganisms and their use.
    Type: Grant
    Filed: October 28, 1986
    Date of Patent: January 10, 1989
    Assignee: Sandoz Ltd.
    Inventors: Dimitri Karamata, Jean-Christophe Piot