Abstract: A control assembly for a steerable medical device shaft, the control assembly may include a steerable-shaft handle; and an elongate docking translating base, including a first-end opening dimensioned to receive and operably engage a portion of a separate medical device handle and a second-end ball. The steerable-shaft handle surrounds a longitudinal passage extending distally from a first-end terminus that includes a socket dimensioned to engagingly receive the second-end ball. The longitudinal passage includes a path in mechanical communication with the first-end opening of the base. The base includes at least two steering wires that extend through the steerable-shaft handle in mechanical communication with a steerable length of a shaft length disposed distal of the steerable-shaft handle.

Abstract: An endoscopic device is provided. The endoscopic device may comprise a distal end and a proximal end. The proximal end may be opposite the distal end. The endoscopic device may further comprise a handle at the proximal end and a tube extending from the handle towards the distal end of the endoscopic device. The endoscopic device may further comprise an accessory channel. The accessory channel may extend through the tube. The endoscopic device may further comprise a slide, the accessory channel extending through the slide, and a curved track disposed adjacent to the proximal end of the endoscopic device. The slide is movable within the curved track to cause movement of the accessory channel within the tube.

Abstract: A medical device for facilitating a minimally invasive surgical procedure may include a housing and an arm. The housing may be configured for engagement around an outer circumferential surface of an endoscope and may include a first cavity. The arm may include at least one cutting surface and may be movably received within the first cavity. The arm may be configured to perform a first predetermined movement along at least a first plane at a predetermined frequency.

Abstract: The present embodiments provide systems and methods suitable for delivering a therapeutic agent to a target site. In one example, the system comprises a container for holding the therapeutic agent, and a pressure source having pressurized fluid, wherein the pressure source is in selective fluid communication with at least a portion of the container. A catheter is placed in fluid communication with the container, and has a lumen sized for delivery of the therapeutic agent to a target site. A housing is configured to securely retain the container. The system further comprises a camera having a camera head coupled to the catheter, wherein the camera provides a visual image of the target site during delivery of the therapeutic agent.

Abstract: A scope system is provided including an elongate tube, a movable member extending longitudinally at least partially within a lumen of the elongate tube, and a light on a distal portion of the elongate tube, the light configured to be controlled by proximal or distal movement of the movable member relative to the elongate tube along a longitudinal axis and/or rotational movement of the movable member about the longitudinal axis.

Abstract: A scope system is provided including an elongate tube, a movable member extending longitudinally at least partially within a lumen of the elongate tube, and a light on a distal portion of the elongate tube, the light configured to be controlled by proximal or distal movement of the movable member relative to the elongate tube along a longitudinal axis and/or rotational movement of the movable member about the longitudinal axis.

Abstract: The present embodiments provide systems and methods suitable for delivering a therapeutic agent to a target site. In one example, the system comprises a container for holding the therapeutic agent, and a pressure source having pressurized fluid, wherein the pressure source is in selective fluid communication with at least a portion of the container. A catheter is placed in fluid communication with the container, and has a lumen sized for delivery of the therapeutic agent to a target site. A housing is configured to securely retain the container. The system further comprises a camera having a camera head coupled to the catheter, wherein the camera provides a visual image of the target site during delivery of the therapeutic agent.

Abstract: The present embodiments provide systems and methods suitable for delivering a therapeutic agent to a target site. In one example, the system comprises a container for holding the therapeutic agent, and a pressure source having pressurized fluid, wherein the pressure source is in selective fluid communication with at least a portion of the container. A catheter is placed in fluid communication with the container, and has a lumen sized for delivery of the therapeutic agent to a target site. A housing is configured to securely retain the container. The system further comprises a camera having a camera head coupled to the catheter, wherein the camera provides a visual image of the target site during delivery of the therapeutic agent.

Abstract: An endoscopic device is provided. The endoscopic device may comprise a distal end and a proximal end. The proximal end may be opposite the distal end. The endoscopic device may further comprise a handle at the proximal end and a tube extending from the handle towards the distal end of the endoscopic device. The endoscopic device may further comprise an accessory channel. The accessory channel may extend through the tube. The endoscopic device may further comprise a slide, the accessory channel connected to the slide, and a track disposed adjacent to the proximal end of the endoscopic device. The slide is movable within the track to cause movement of the accessory channel within the tube.

Abstract: Disclosed herein is an endoscope system and a handle for a medical device that allows for rotation of the device when a locking member is disengaged by an operator, but does not allow for rotation when the locking member is engaged. Such a handle allows for an operator to maintain the position of an endoscope even when the operator removes his or her hand from the controls of the scope.

Abstract: A medical scope device may have a first steerable device extending to a distal end of the medical scope device. The medical scope device may also include a second steerable device extending to the distal end of the medical scope device. The device may also include a first steering actuator. A selector switch may be mechanically coupled to the first steering actuator, where the first steering actuator controls a movement of a distal end of the first steerable device when the selector switch is in a first position, and where the first steering actuator controls a movement of a distal end of the second steerable device when the selector switch is in a second position.

Abstract: A bipolar sphincterotome may include an elongate tubular member longitudinally extending from a proximal portion to a distal portion, an active path comprising a cutting edge exposed outside of the elongate tubular member, and a return electrode disposed over an outer surface of the elongate tubular member. In various embodiments, in an axial cross-section of the bipolar sphincterotome, the return electrode does not intersect a transverse axis. In addition or alternatively, a minimum distance between the cutting edge and the return electrode is at least about 0.050 inches.

Abstract: Disclosed herein is an endoscope system and a handle for a medical device that allows for rotation of the device when a locking member is disengaged by an operator, but does not allow for rotation when the locking member is engaged. Such a handle allows for an operator to maintain the position of an endoscope even when the operator removes his or her hand from the controls of the scope.

Abstract: A scope system including a handle that may be changed from a locked configuration to an unlocked configuration by removing a removable handle lock is provided. The handle includes features for storage of a movable elongate member on the side of the handle when the handle is in the locked configuration. In the unlocked configuration, the movable elongate member can be connected to the handle to perform desired procedures.

Abstract: A scope system is provided including an elongate tube, a movable member extending longitudinally at least partially within a lumen of the elongate tube, and a light on a distal portion of the elongate tube, the light configured to be controlled by proximal or distal movement of the movable member relative to the elongate tube along a longitudinal axis and/or rotational movement of the movable member about the longitudinal axis.

Abstract: An endoscopic device is provided. The endoscopic device may comprise a distal end and a proximal end. The proximal end may be opposite the distal end. The endoscopic device may further comprise a handle at the proximal end and a tube extending from the handle towards the distal end of the endoscopic device. The endoscopic device may further comprise an accessory channel. The accessory channel may extend through the tube. The endoscopic device may further comprise a slide, the accessory channel extending through the slide, and a curved track disposed adjacent to the proximal end of the endoscopic device. The slide is movable within the curved track to cause movement of the accessory channel within the tube.

Abstract: Medical devices for repairing defects in tissue, such as perforations in the tympanic membrane of an animal, methods of manufacturing medical devices, methods of implanting a medical device in a defect in a tissue; and methods of repairing a defect in a tissue are described. In one form, a medical device includes an overlay member having multiple arms and defining an overlay member passageway, an underlay member having multiple flaps and defining an underlay member passageway, and a securement member extending through the overlay member passageway and the underlay member passageway. In methods, the multiple flaps of the underlay member can be sequentially advanced into a defect in a tissue, such as a perforation in a tympanic membrane of an animal.

Abstract: Disclosed herein is a medical device including a dynamic seal and a movable member. The device allows the movable member to translate proximally and distally through the dynamic seal while fluid does not flow proximally to the dynamic seal member.

Abstract: A method of treating a lesion in a gastrointestinal tract and an injectate system are provided. The method includes injecting a crosslinkable gel into a first tissue layer, the crosslinkable gel increasing a volume of the first tissue layer. The method also includes providing a crosslinker and resecting a portion of a first tissue layer having the increased volume away from a second tissue layer creating an exposed region in a remaining portion of the first layer and leaving a portion of the gel covering at least a portion of the exposed region. The injectate system includes a crosslinkable gel and a crosslinker where the crosslinkable gel and the crosslinker form a crosslinked gel having a compressive modulus of about 10-500 kPa.

Abstract: A method of treating a lesion in a gastrointestinal tract and an injectate system are provided. The method includes injecting a crosslinkable gel into a first tissue layer, the crosslinkable gel increasing a volume of the first tissue layer. The method also includes providing a crosslinker and resecting a portion of a first tissue layer having the increased volume away from a second tissue layer creating an exposed region in a remaining portion of the first layer and leaving a portion of the gel covering at least a portion of the exposed region. The injectate system includes a crosslinkable gel and a crosslinker where the crosslinkable gel and the crosslinker form a crosslinked gel having a compressive modulus of about 10-500 kPa.