Abstract: A liner (100) and closure (106) are provided for being initially assembled and subsequently installed on a container (104) of a product to create a package (107, 107A). The liner (100) is provided for being disposed between, and sealed to, the container (104) and the closure (106) mounted thereon. The liner (100) includes a metallic substrate layer (200) that is an aluminum alloy and that is located between first and second heat-sealable layers (212, 200), respectively. The liner (100) has a through hole (252), and the metallic substrate layer (200) has a laterally inward edge surface (210) that is exposed at the through hole (252).

Abstract: A liner (100) and closure (106) are provided for being initially assembled and subsequently installed on a container (104) of a product to create a package (107, 107A). The liner (100) is provided for being disposed between, and sealed to, the container (104) and the closure (106) mounted thereon. The liner (100) includes a metallic substrate layer (200) that is an aluminum alloy and that is located between first and second heat-sealable layers (212, 200), respectively. The liner (100) has a through hole (252), and the metallic substrate layer (200) has a laterally inward edge surface (210) that is exposed at the through hole (252).

Abstract: A closure (20) is provided to selectively permit or restrict communication between the exterior and the interior of a system that has an opening between the exterior and interior. The closure (20) includes a closure body (24) that defines an access passage (30) and a membrane (60) that initially occludes the access passage (30). The connection of the membrane (60) to the body (24) is defined by a tearable portion (68) of material that defines a tear path along which the material can be torn. The tear path has; (A) a first separation path (80) where separation of the membrane (60) from the body (24) initially originates; and (B) a second separation path (90) where separation of the membrane (60) from the body (24) terminates. The second separation path (90) has a generally tapered configuration.

Abstract: A closure (20, 2GA, 2GB) is provided for a system with an opening. The closure (20, 20A, 20B) has a body (24, 24A, 24B) with an outer end (32, 32B) and a through passage (30, 3GB) for communicating with the system opening. The body (24, 24A, 24B) has a membrane (60, 60B) mitially occluding the through passage (30, 30B). The closure (20, 20A, 20B) has a lid (26, 26A. 26B) to accommodate movement relative to the body (24. 24A, 24B) between a closed position restricting access to the through passage (30, 30B) and an open position permitting greater access to the through passage (30, 30B). The body (24, 24A, 24B) thither has a separation member (70, 7GB) that can be engaged by a user to separate at least a part of the membrane (60, 60B) from the body (24, 24 A. 24B).

Abstract: A closure (20) is provided to selectively permit or restrict communication between the exterior and the interior of a system that has an opening between the exterior and interior. The closure (20) includes a closure body (24) that defines an access passage (30) and a membrane (60) that initially occludes the access passage (30). The connection of the membrane (60) to the body (24) is defined by a tearable portion (68) of material that defines a tear path along which the material can be torn. The tear path has; (A) a first separation path (80) where separation of the membrane (60) from the body (24) initially originates; and (B) a second separation path (90) where separation of the membrane (60) from the body (24) terminates. The second separation path (90) has a generally tapered configuration.

Abstract: A closure (20, 2GA, 2GB) is provided for a system with an opening. The closure (20, 20A, 20B) has a body (24, 24A, 24B) with an outer end (32, 32B) and a through passage (30, 3GB) for communicating with the system opening. The body (24, 24A, 24B) has a membrane (60, 60B) mitially occluding the through passage (30, 30B). The closure (20, 20A, 20B) has a lid (26, 26A. 26B) to accommodate movement relative to the body (24. 24A, 24B) between a closed position restricting access to the through passage (30, 30B) and an open position permitting greater access to the through passage (30, 30B). The body (24, 24A, 24B) thither has a separation member (70, 7GB) that can be engaged by a user to separate at least a part of the membrane (60, 60B) from the body (24, 24A. 24B).

Abstract: A closure (20, 20A) is provided for a container that has an opening to the container interior wherein contents may be stored. The closure (20, 20A) includes the following: (A) a closure body (30, 30A) defining (i) at least one pour aperture (50) that can communicate with the container opening and that can accommodate pouring out of the contents through the pour aperture (50), and (ii) at least one vent aperture (60) that can. communicate with the container opening and that can accommodate the in-venting of ambient atmosphere through the vent aperture into the container; and (B) a lid (32, 32A) for closing the closure (20, 20A). The pour aperture (50) has a curved configuration extending laterally on each side of a central axis line (A) that bisects the closure body (30), and the vent aperture (60) is further defined by a downwardly extending vent tube.

Abstract: A dispensing closure system is provided for a container that has an opening to the container interior. The preferred embodiment of the system includes a closure having a closure body for extending from the container at the container opening and a lid hingedly attached to the closure body. The closure body has a dispensing spout, and the lid includes a hollow spud for entering the spout. A spud rim can be provided on the spud, extending inwardly towards the hollow interior of the spud. A lid rim can additionally or alternatively be provided on the inside surface of the lid, positioned within the hollow interior of the spud.

Abstract: A dispensing closure system is provided for a container that has an opening to the container interior. The preferred embodiment of the system includes a closure having a closure body for extending from the container at the container opening and a lid hingedly attached to the closure body. The closure body has a dispensing spout, and the lid includes a hollow spud for entering the spout. A spud rim can be provided on the spud, extending inwardly towards the hollow interior of the spud. A lid rim can additionally or alternatively be provided on the inside surface of the lid, positioned within the hollow interior of the spud.

Abstract: A dispensing closure system is provided for a container that has an opening to the container interior. The preferred embodiment of the system includes a closure having a closure body for extending from the container at the container opening and a lid hingedly attached to the closure body. The closure body has a dispensing spout, and the lid includes a hollow spud for entering the spout. A spud rim can be provided on the spud, extending inwardly towards the hollow interior of the spud. A lid rim can additionally or alternatively be provided on the inside surface of the lid, positioned within the hollow interior of the spud.

Abstract: A method for separating nucleic acid from a liquid sample, said method comprising the steps of causing a liquid sample containing or suspected of containing said nucleic acid to flow along a bibulous membrane, for example of a conventional lateral flow device, so that nucleic acid is distributed along the length of the membrane. The nucleic acid may be detected on the membrane.

Abstract: A method for the determination of a target analyte in a sample, said method comprising: a) applying a liquid sample suspected of containing said target analyte to a solid support capable of allowing lateral flow of liquid there through, which support has diffusibly arranged thereon, (i) either (a) a labeled binding partner for said analyte or (b) a labeled analogue of said analyte, and (ii) a labeled control reagent; b) allowing the sample, labeled binding partner for said analyte or a labeled analogue of said analyte and labeled control reagent to flow through a detection zone on said solid support; c) allowing the sample, labeled binding partner for said analyte or a labeled analogue of said analyte and labeled control reagent to flow through a control zone; and d) detecting the labeled density in the detection zone and the label density in the control zone and comparing these densities.

Abstract: A dispensing closure system is provided for a container that has an opening to the container interior. The preferred embodiment of the system includes a closure having a closure body for extending from the container at the container opening and a lid hingedly attached to the closure body. The closure body has a dispensing spout, and the lid includes a hollow spud for entering the spout. A spud rim can be provided on the spud, extending inwardly towards the hollow interior of the spud. A lid rim can additionally or alternatively be provided on the inside surface of the lid, positioned within the hollow interior of the spud.

Abstract: A method for separating nucleic acid from a liquid sample, said method comprising the steps of causing a liquid sample containing or suspected of containing said nucleic acid to flow along a bibulous membrane, for example of a conventional lateral flow device, so that nucleic acid is distributed along the length of the membrane. The nucleic acid may be detected on the membrane.

Abstract: A method for the determination of a target analyte in a sample, said method comprising: a) applying a liquid sample suspected of containing said target analyte to a solid support capable of allowing lateral flow of liquid therethrough, which support has diffusibly arranged thereon, (i) either (a) a labelled binding partner for said analyte or (b) a labelled analogue of said analyte, and (ii) a labelled control reagent; b) allowing the sample, labelled binding partner for said analyte or a labelled analogue of said analyte and labelled control reagent to flow through a detection zone on said solid support, wherein in the case of (i) (a) above, a predetermined amount of an analogue of the target analyte is immobilised, or, in the case of (i) (b) above a predetermined amount of a binding partner for said analyte or, labelled analogue is immobilised; c) allowing the sample, labelled binding partner for said analyte or a labelled analogue of said analyte and labelled control reagent to flow through a control zone

Abstract: A closure system is provided with a peripheral wall for extending from a container. A lid is molded with the peripheral wall as a unitary structure connected by a linear array of spaced-apart floppy hinge segments.

Abstract: A dispensing closure system is provided with two or more dispensing apertures and two or more pivotable lids. Each lid can be selectively opened and retained in a fully opened orientation. In a preferred form of the invention, the lids are incorporated in a top that is snap-fitted into a closure body which defines the dispensing apertures.