Patents by Inventor Christopher A. Holmes

Christopher A. Holmes has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Novel peptides that bind to the erythropoietin receptor
    Publication number: 20050137329
    Abstract: The present invention relates to peptide compounds that are agonists of the erythropoietin receptor (EPO-R). The invention also relates to therapeutic methods using such peptide compounds to treat disorders associated with insufficient or defective red blood cell production. Pharmaceutical compositions, which comprise the peptide compounds of the invention, are also provided.
    Type: Application
    Filed: May 12, 2004
    Publication date: June 23, 2005
    Applicant: Affymax, Inc.
    Inventors: Christopher Holmes, Qun Yin, Guy Lalonde, Peter Schatz, David Tumelty, Balu Palani, Genet Zemede
  • Novel poly(ethylene glycol) modified compounds and uses thereof
    Publication number: 20050107297
    Abstract: The present invention relates to a peptide-based compound comprising a peptide moiety and a poly(ethylene glycol) moiety wherein the poly(ethylene glycol) moiety (preferably linear) has a molecular weight of more than 20 KDaltons (preferably from 20 to 60 KDaltons). The peptide moiety may be monomeric, dimeric or oligomeric. Such peptide-based compounds may optional include a linker moiety and/or a spacer moiety.
    Type: Application
    Filed: May 12, 2004
    Publication date: May 19, 2005
    Inventors: Christopher Holmes, David Tumelty, Qun Yin
  • Perfluoro sulfonyl halides and related species as polymer support modifiers
    Publication number: 20040106151
    Abstract: Activated Supports, support-bound activators, strongly acidic supports, and silylating supports are provided; the activated support having the formula (I) wherein L is a linking group component; X is F, CL, OH, and trisubstituted silyloxy; and the shaded circle represents a solid or semi-solid support. Methods of using the activated supports in solid phase organic sync) thesis are also provided.
    Type: Application
    Filed: July 10, 2003
    Publication date: June 3, 2004
    Inventors: Christopher Holmes, Yijun Pan
  • Perfluoro sulfonyl halides and related species as polymer support modifiers
    Publication number: 20030124612
    Abstract: Activated Supports, support-bound activators, strongly acidic supports, and silylating supports are provided; the activated support having the formula: 1
    Type: Application
    Filed: January 11, 2002
    Publication date: July 3, 2003
    Inventors: Christopher Holmes, Yijun Pan
  • Methods for hard-tagging an encoded synthetic library
    Patent number: 6368874
    Abstract: Disclosed are chemical encryption methods for determining the structure of compounds formed in situ on solid supports by the use of specific amines tags which, after compound synthesis, can be deencrypted to provide the structure of the compound found on the support.
    Type: Grant
    Filed: November 17, 1999
    Date of Patent: April 9, 2002
    Assignee: Affymax, Inc.
    Inventors: Mark A. Gallop, Eric Gordon, Zhi-Jie Ni, Derek MacLean, Christopher Holmes, William Fitch, Nikhil Shah
  • Methods for hard-tagging an encoded synthetic library
    Patent number: 5846839
    Abstract: Disclosed are chemical encryption methods for determining the structure of compounds formed in situ on solid supports by the use of specific amines tags which, after compound synthesis, can be deencrypted to provide the structure of the compound found on the support.
    Type: Grant
    Filed: December 22, 1995
    Date of Patent: December 8, 1998
    Assignee: Glaxo Group Limited
    Inventors: Mark A. Gallop, Eric Gordon, Zhi-Jie Ni, Derek MacLean, Christopher Holmes, William Fitch, Nikhil Shah