Abstract: A computer implemented method of simulating audio signals in a virtual environment, wherein the virtual environment comprises a first room comprising an audio source, a second room comprising an audio receiver, and a third room in-between the first and second rooms, the method comprising: simulating the propagation of an audio signal in the first room and outputting the simulated audio signal to the third room; modifying the simulated audio signal by a predetermined function; generating a modified audio signal and outputting the modified audio signal to the second room.

Abstract: The disclosure generally relates to binding proteins that comprise antigen binding sites, a T cell receptor binding site, and a T cell co-stimulatory molecule binding site. The disclosure also relates to pharmaceutical compositions comprising such binding proteins, nucleic acid molecules encoding such binding proteins, and vectors comprising such nucleic acid molecules. The disclosure further relates to methods of treating a disorder or condition using such binding proteins and pharmaceutical compositions, binding proteins and pharmaceutical compositions for use in the treatment of a disorder or condition, and the use of such binding proteins and pharmaceutical compositions for the manufacture of a medicament for treating a disorder or condition.

Abstract: A computer-implemented method of simulating the propagation of an audio signal between an audio source and receiver in a virtual environment, the virtual environment comprising one or more sound-reflective objects, the method comprising: simulating a plurality of audio paths for propagating the audio signal between the audio source and receiver within the virtual environment, one or more of the simulated audio paths comprising a reflection from a sound reflective object; and for one or more of the audio paths simulated, applying a deviation of the effective simulated position of one or more of the audio source, receiver and sound reflective object within the virtual environment, where the effective simulated position is used to determine a path delay associated with the simulated audio path.

Abstract: A computer-implemented method of simulating the propagation of an audio signal between a source and receiver in a virtual environment is disclosed. The method comprising: simulating reflections of an audio signal within the virtual environment to determine a plurality of audio paths between the source and receiver; determining an input audio signal to be propagated between the source and receiver by the plurality of audio paths; determining one or more audio paths having a delay that causes interference in the input audio signal; applying an adjustment to the determined audio paths to reduce the interference in the audio signal caused by the one or more audio paths. In this way, an audio simulation may be adapted according to the specific audio signal to reduce phase artefacts.

Abstract: A rotary machine seal assembly (200) includes seal segments (102) configured to circumferentially extend around a rotor (108) between a stator (106) and the rotor (108) of a rotary machine. One or more seal segments include a shoe plate (110, 410, 710, 910), a seal base (112, 412, 712, 912), and at least one intermediate member (114, 414, 714). The shoe plate is disposed along the rotor. The seal base is disposed radially outward of the shoe plate. At least one intermediate member is coupled to and disposed between the seal base and the shoe plate. The at least one intermediate member includes an actuator portion (302, 402, 702, 902) having first coefficient of thermal expansion and a constrictor portion (304, 404, 704, 904) having a different, second coefficient of thermal expansion.

Abstract: Disclosed herein is a computer-implemented method comprising: aggregating option evaluation data for a plurality of options and for a plurality of predefined criteria; graphically displaying the user modifiable chart comprising the plurality of graphical representations of the aggregated option evaluation data, wherein: each graphical representation depicts data points visually plotted with weights, the plurality of graphical representations for the plurality of predefined criteria are visually ordered according to a rank of the plurality of predefined criteria, and the weights are based on the rank of the plurality of predefined criteria; detecting a first user input modifying the rank of at least one predefined criterion; in accordance with the first user input, automatically updating the weights of the data points; and displaying an updated user modifiable chart comprising the plurality of graphical representations of the aggregated option evaluation data.

Abstract: Provided are methods for preparing sterilized, gelled, solubilized extracellular matrix (ECM) compositions useful as cell growth substrates. Also provided are compositions prepared according to the methods as well as uses for the compositions. In one embodiment a device, such as a prosthesis, is provided which comprises an inorganic matrix into which the gelled, solubilized ECM is dispersed to facilitate in-growth of cells into the ECM and thus adaptation and/or attachment of the device to a patient.

Abstract: Embodiments disclosed herein relate to systems and methods for adapting ambulatory infusion pump systems to operate with different types of continuous glucose monitoring (CGM) sensors. Infusion pump systems as disclosed herein can include software configured to store characteristics for different types of CGM sensors and can interface with a given type of CGM sensor based on specific characteristics and requirements of the given type of sensor.

Abstract: A controller of a machine identifies that a battery of the machine is connected to an electrical power connector component. The controller then causes one or more charging components of the battery of the machine to be enabled, then cause one or more electrical components associated with the battery of the machine to be enabled, then causes one or more cooling components of the machine to be enabled, then causes one or more propulsion components of the machine to be disabled, then causes one or more accumulator components of a hydraulic system of the machine to bleed, and then causes one or more non-accumulator components of the hydraulic system of the machine to be enabled. In this way, the controller causes the battery of the machine to enter into a charging state.

Abstract: A portable electronic device for assisting a user in locating a condition of a system within a real-world environment is disclosed. The portable electronic device may include a display, an image capture device, and a processor. The processor may be configured to receive, from the image capture device, image data associated with a representation of the real-world environment and to align a virtual model with the real-world environment. The processor may also be configured to receive information associated with the condition of the system and to determine a location in the virtual model corresponding to the condition of the system. Further, the processor may provide a graphical indicator to be displayed over the representation of the real-world environment. The graphical indicator may be displayed at a location on the display that corresponds to a physical location of the condition of the system in the real-world environment.

Abstract: A method and system for migrating a payment instrument portfolio. A payment network computer receives a payment instrument portfolio conversion request message from an issuer computer to convert a payment instrument portfolio from a prior payment instrument scheme to a new payment instrument portfolio based on a new payment instrument scheme. The request message includes information about existing payment instrument references from the prior payment instrument scheme. The payment network computer creates enrollments based on the information about the existing payment instrument references and sends a portfolio migration event notification message to a payment instrument requestor partner computer associated with a payment network payment instrument requestor identifier subscribed to a new event type for the payment instrument portfolio migration.

Abstract: Systems and methods for providing visual indications of generative model responses can include obtaining a user input and processing the user input with a generative model to generate a model-generated-response. The systems and methods can process the model-generated response and an image of an environment to generate an augmented image. The augmented image can include visual indicators of the model-generated response, which can include annotating the image based on detected features within the image. Generation of the augmented image can include object detection and annotation based on the content of the model-generated response.

Abstract: A product description generating system dynamically generates a description of an item based on one or more images. The product description generating system includes an attribute machine learning system that receives images of the item and determines at least one attribute value and corresponding prediction confidence value based on the image data. The user review interface provides an interface for reviewing attribute values generated by the attribute machine learning system. If the prediction confidence value is outside a threshold, then the attribute value is reviewed by a user via the user review interface. If, on the other hand, the prediction confidence value is within a threshold, then the attribute value is used to generate the description without user review. The user review interface groups items to be reviewed by taxon and facilitates user review of many items at scale.

Abstract: Embodiments are disclosed for active cancellation of noise in motion sensor signals. In some embodiments, a method comprises: obtaining a motion sensor signal from a motion sensor; obtaining a reference signal indicative of parasitic vibration from a vibration source mechanically coupled to the motion sensor; generating, using an adaptive noise canceller, an estimate of the parasitic vibration; and using the estimated parasitic vibration to cancel the parasitic vibration from the motion sensor signal.

Abstract: A computer implemented method is provided. A number of processor units identify a number of certificates for a device within a network to obtain a file path for each certificate. The number of processor units perform an internal scan of the device to obtain a port number for each active port associated with network protocol on the device. The number of processor units identify a certificate chain associated with each port number based on the network protocol for the device. The number of processor units compare content for each certificate from the number of certificates to the certificate chains for the device to generate a number of matches. The number of processor units generate a data structure including the file path of the certificate for each port on the device based on the number of matches.

Abstract: Embodiments of the inventive subject matter are directed to retirement plan optimization. By collecting client information, systems and methods of the inventive subject matter are configured to develop scenarios for a user. From those scenarios, multiple simulations can be run. Each scenario features scenario parameters, and each simulation features simulation parameters. Scenario parameters can include ranges of values or a set of different possible values. For a given scenario, many simulations can be run, where each simulation has a corresponding set of simulation parameters, and where each set of simulation parameters features set values for each of the scenario parameters for that scenario. After running multiple simulations for each scenario, high performing simulations can be identified based on a base case performance and based on one or more optimization goals. Once high performing simulations are identified, actionable retirement plans can be developed therefrom.

Abstract: The application provides a computer-implemented method for simulating a reflected audio path in a virtual environment, the virtual environment comprising a source, a receiver, an obstacle, and a sound-reflective boundary, the reflected audio path associated with reflection at the sound-reflective boundary, and the method comprising: simulating, by an image-source method, the reflected audio path between the source and the receiver, the image-source method comprising: generating, by mirroring the source in the sound-reflective boundary, a mirror image source, and determining a simulated reflected audio path along a line segment between the receiver and the mirror image source; generating, by mirroring the obstacle in the sound-reflective boundary, a mirror image obstacle; performing a line-of-sight check between the receiver and the mirror image source; and, when at least one of the obstacle and the mirror image obstacle lies along the line segment between the mirror image source and the receiver, performing a

Abstract: Bone anchor assemblies are disclosed herein that can provide for improved fixation as compared with traditional bone anchor assemblies. An exemplary assembly can include a bracket or wing that extends down from the receiver member. The distal portion of the wing can define a bone anchor opening through which one or more auxiliary bone anchors can be disposed to augment the fixation of the assembly's primary bone anchor. A distal surface of the distal portion of the wing can be obliquely angled relative to a proximal-distal axis of the spanning portion to face one of a caudal direction or a cephalad direction. A distal surface of the distal portion of the wing can be obliquely angled relative to the proximal-distal axis of the spanning portion to face one of a medial direction or a lateral direction. Surgical methods using the bone anchor assemblies described herein are also disclosed.

Abstract: Methods, systems, and apparatus, including computer programs encoded on computer storage media, for secure communications in a digital engineering ecosystem. In some implementations, a digital platform receives a request from a user device to interact with a digital model. The digital platform determines whether a user operating the user device is authorized. In response to determining the user is authorized to access the digital platform, the digital platform generates a token that provides the user with access to the digital platform. The digital platform determines whether the request includes malicious activity. In response to determining that the request is absent of the malicious activity, the digital platform executes a digital thread that executes one or more operations using digital tools and the digital model. The digital platform provides data indicative of the one or more operations executing the digital thread to the user device.