Abstract: Embodiments of the disclosure are drawn to apparatuses and methods for a rotating optical reflector. Optical systems may have a limited field of view, and so in order to expand the area that the optical system collects data from, the field of view of the optical system may be scanned across a target area. The present disclosure is directed to a rotating optical reflector, which includes a transmissive layer which refracts light onto a reflective layer, which has a normal which is not parallel to the axis about which the optical reflector is rotated. The optical reflector may be both statically and dynamically balanced, which may allow an increased size of the optical reflector, which in turn may increase the aperture of an optical system (e.g., a lidar system) using the rotating optical reflector.

Abstract: A disposable absorbent article may include a chassis that includes a topsheet, a backsheet, and an absorbent core disposed between the topsheet and the backsheet; and a leg gasketing system and a waist gasketing element. The leg gasketing system may include an inner cuff and an outer cuff; the inner cuff may include an inner cuff folded edge and an inner cuff material edge and the outer cuff may include an outer cuff folded edge and an outer cuff material edge such that the web of material is folded laterally inward to form the outer cuff folded edge and folded laterally outward to form the inner cuff folded edge. The leg gasketing system may also include a leg gasketing system pocket with an opening on an inboard longitudinal edge of the pocket.

Abstract: A process of evaluating whether to open a new car wash at a new geographic location includes establishing the geographic location for consideration, obtaining real-time data generated for a plurality of existing car washes at or near the geographic location, and categorizing the real-time data obtained for each of the existing car washes into a plurality of defined categories. A data structure linking the real-time data obtained with unique location identifiers is generated, and demographic information is accessed for the respective locations using the location identifiers. An artificial neural network generates a financial prediction indicating an expected financial performance of the car wash if constructed at the geographic location based on the data structure. A determination can be made whether to construct the new wash at the geographic location based on whether an expected financial performance of the car wash at the geographic location satisfies a minimum performance threshold.

Abstract: A disposable absorbent article may include a chassis that includes a topsheet, a backsheet, and an absorbent core disposed between the topsheet and the backsheet; and a leg gasketing system and a waist gasketing element. The leg gasketing system may include an inner cuff and an outer cuff; the inner cuff may include an inner cuff folded edge and an inner cuff material edge and the outer cuff may include an outer cuff material edge such that the web of material is folded outward to form the inner cuff folded edge. When tested by the Blowout Method Test as described herein, the disposable absorbent article has a Blowout Percent Leakage of less than about 9.0%.

Abstract: An example robot includes a first actuator and a second actuator connecting a first portion of a first member of the robot to a second member of the robot. Extension of the first actuator accompanied by retraction of the second actuator causes the first member to roll in a first roll direction. Retraction of the first actuator accompanied by extension of the second actuator causes the first member to roll in a second roll direction. A third actuator connects a second portion of the first member to the second member. Extension of the third actuator accompanied by retraction of both the first and second actuators causes the first member to pitch in a first pitch direction. Retraction of the third actuator accompanied by extension of both the first and second actuators causes the first member to pitch in a second pitch direction.

Abstract: Described herein are methods for the expression and purification of Cas13a and methods for detecting target RNA using Cas13a.

Abstract: The present invention relates to novel Amido-Substituted Heterocycle Compounds of Formula (I): and pharmaceutically acceptable salts thereof, wherein R1, R2, R3, R4, and R5 are as defined herein. The present invention also relates to compositions comprising at least one Amido-Substituted Heterocycle Compounds for treating or preventing a herpesvirus infection in a patient.

Abstract: Embodiments of the disclosure are drawn to apparatuses and methods for a rotating optical reflector. Optical systems may have a limited field of view, and so in order to expand the area that the optical system collects data from, the field of view of the optical system may be scanned across a target area. The present disclosure is directed to a rotating optical reflector, which includes a transmissive layer which refracts light onto a reflective layer, which has a normal which is not parallel to the axis about which the optical reflector is rotated. The optical reflector may be both statically and dynamically balanced, which may allow an increased size of the optical reflector, which in turn may increase the aperture of an optical system (e.g., a lidar system) using the rotating optical reflector.

Abstract: Backpack strap accessory methods, systems, and device are provided in accordance with various embodiments. Some embodiments include a device that may include a backpack accessory. The device may include one or more attachment appendages coupled with the backpack accessory where the one or more attachment appendages are configured to couple the backpack accessory with a backpack shoulder strap. The device may include one or more rigid members coupled with the backpack accessory such that at least one of the rigid members hinder a motion of the backpack accessory in at least one direction along a length of the backpack shoulder strap with respect to a hardware coupled with the backpack shoulder strap. Some embodiments include one or more apertures formed with respect to the attachment appendages such that a sternum strap coupled with the backpack shoulder strap passes through at least one of the one or more apertures.

Abstract: The present invention relates to novel Amido-Substituted Heterocycle Compounds of Formula (I): and pharmaceutically acceptable salts thereof, wherein R1, R2, R3, R4, R7, and R8 are as defined herein. The present invention also relates to compositions comprising at least one Amido-Substituted Heterocycle Compound, and methods of using the Amido-Substituted Heterocycle Compounds for treating or preventing a herpesvirus infection in a patient.

Abstract: This invention pertains to mutant Cas9 nucleic acids and proteins for use in CRISPR/Cas endonuclease systems, and their methods of use. In particular, the invention pertains to an isolated mutant Cas9 protein, wherein the isolated mutant Cas9 protein is active in a CRISPR/Cas endonuclease system, wherein the CRISPR/Cas endonuclease system displays reduced off-target editing activity and maintained on-target editing activity relative to a wild-type CRISPR/Cas endonuclease system. The invention also includes isolated nucleic acids encoding mutant Cas9 proteins, ribonucleoprotein complexes and CRSPR/Cas endonuclease systems having mutant Cas9 proteins that display reduced off-target editing activity and maintained on-target editing activity relative to a wild-type CRISPR/Cas endonuclease system.

Abstract: A containment plow adapted to be mounted to a vehicle such as a skid steer, a wheeled loader, or a tractor, comprises a moldboard frame, a moldboard mounted to the moldboard frame, a moldboard cutting edge mounted to a lower edge of the moldboard and comprising a plurality of cutting edge segments, each moldboard cutting edge segment mounted so as to have two rotational degrees of freedom movement relative to the moldboard and one translational degree of freedom movement relative to the moldboard, and a moldboard extension and wing assembly connected to the moldboard frame adjacent each end of the moldboard.

Abstract: A containment plow adapted to be mounted to a vehicle such as a skid steer, a wheeled loader, or a tractor comprises a moldboard frame, a moldboard mounted to the moldboard frame, a wing pivotally connected to the moldboard frame adjacent each end of the moldboard, a moldboard cutting edge mounted to a lower edge of the moldboard and comprising a plurality of cutting edge segments, and a wing cutting edge mounted to a lower edge of each wing. Each moldboard cutting edge segment is mounted so as to have two rotational degrees of freedom movement relative to the moldboard and one translational degree of freedom movement relative to the moldboard. Each wing cutting edge is mounted so as to have two rotational degrees of freedom movement relative to the wing.

Abstract: The present teachings provide a camera housing that includes a first housing portion, a second housing portion, a hinge, a latch mechanism, and protrusions. The first housing portion forms a first portion of a cavity. The second housing portion forms a second portion of the cavity The hinge is located within the first housing portion so that the first housing portion is divided into a first piece and a second piece. The hinge movably connects the first housing portion to the second housing portion so that the second housing portion is movable relative to the first housing. The latch mechanism is movable between an open position and a closed position. The protrusion extend from a third housing portion, and the third housing portion is located opposite the first housing portion with respect to the cavity.

Abstract: A band pass filter circuit for transmitting electromagnetic signals within a desired frequency band includes a transmission line extending between input and output terminals, a high pass filter connected to the transmission line for blocking the transmission of signals falling below the operational frequency band, and a low pass filter connected to the transmission line for blocking the transmission of signals falling above the operational frequency band. Additionally, a primary suppressor connects the transmission line to ground and suppresses unwanted transients on the transmission line. A set of supplemental suppressors connects the transmission line to ground and suppresses any residual transient energy on the transmission line after treatment by the primary suppressor. Each supplemental suppressor is paired in parallel with a higher-valued capacitor from the low pass filter in order to minimize the effect of its parasitic capacitance on the band pass characteristics of the circuit.

Abstract: A vector processing unit is described, and includes processor units that each include multiple processing resources. The processor units are each configured to perform arithmetic operations associated with vectorized computations. The vector processing unit includes a vector memory in data communication with each of the processor units and their respective processing resources. The vector memory includes memory banks configured to store data used by each of the processor units to perform the arithmetic operations. The processor units and the vector memory are tightly coupled within an area of the vector processing unit such that data communications are exchanged at a high bandwidth based on the placement of respective processor units relative to one another, and based on the placement of the vector memory relative to each processor unit.

Abstract: A circuit comprises an input register configured to receive an input vector of elements, a control register configured to receive a control vector of elements, wherein each element of the control vector corresponds to a respective element of the input vector, and wherein each element specifies a permutation of a corresponding element of the input vector, and a permute execution circuit configured to generate an output vector of elements corresponding to a permutation of the input vector. Generating each element of the output vector comprises accessing, at the input register, a particular element of the input vector, accessing, at the control register, a particular element of the control vector corresponding to the particular element of the input vector, and outputting the particular element of the input vector as an element at a particular position of the output vector that is selected based on the particular element of the control vector.

Abstract: A spreader comprises a hopper for containing sand, salt or other granular material to be spread upon snow or ice on paved surfaces, the hopper being adapted to be installed in or on a bed of a truck, the hopper having a trough, a shaftless auger positioned in the trough, an auger motor for driving the auger, a spinner positioned at one end of the auger for slinging the granular material upon the snow or ice, a spinner motor for driving the spinner, and at least one keeper supported by the trough and extending over the auger for retaining the auger in place during operation and thereby reducing flexure of the auger and resulting loss of efficiency of material transport by the auger during operation of the spreader.

Abstract: A camera housing having a first housing portion that forms a first portion of a cavity to receive a camera and a second housing portion. The second housing portion that forms a second portion of the cavity to receive the camera. A hinge movably connecting the first housing portion to the second housing portion so that the second housing portion is movable relative to the first housing portion to expose the cavity. Fastening structures configured to connect the first housing portion to the second housing portion when the camera housing is in a closed position, wherein one of the fastening structures include a first latch component and a second latch component. The first latch component connected to the first housing portion.

Abstract: A circuit for performing neural network computations for a neural network comprising a plurality of layers, the circuit comprising: activation circuitry configured to receive a vector of accumulated values and configured to apply a function to each accumulated value to generate a vector of activation values; and normalization circuitry coupled to the activation circuitry and configured to generate a respective normalized value from each activation value.