Patents by Inventor Christopher ABBOSH

Christopher ABBOSH has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • METHODS AND SYSTEMS FOR TUMOUR MONITORING
    Publication number: 20240412813
    Abstract: The present invention provides a computer-implemented method for estimating the cancer cell fraction (CCF) of at least one tumour-specific mutation in a subject. Also provided are related methods for monitoring the clonal dynamics of a tumour, monitoring a treatment of the tumour and methods for treating a subject having a cancer, as well as systems for implementing the methods of the invention.
    Type: Application
    Filed: October 7, 2022
    Publication date: December 12, 2024
    Applicant: Cancer Research Technology Limited
    Inventors: Alexander Mark Frankell, Christopher Abbosh, Robert Charles Swanton
  • Methods for lung cancer detection
    Patent number: 12146195
    Abstract: The invention provides methods for detecting single nucleotide variants in lung cancer, especially stage 3a lung adenocarcinoma and lung squamous cell carcinoma. Additional methods and compositions, such as reaction mixtures and solid supports comprising clonal populations of nucleic acids, are provided.
    Type: Grant
    Filed: April 17, 2017
    Date of Patent: November 19, 2024
    Assignee: Natera, Inc.
    Inventors: Bernhard Zimmermann, Tudor Pompiliu Constantin, Raheleh Salari, Huseyin Eser Kirkizlar, Robert Charles Swanton, Mariam Jamal-Hanjani, Christopher Abbosh, Gareth Wilson
  • METHOD OF DETECTING TUMOUR RECURRENCE
    Publication number: 20200248266
    Abstract: The invention relates to subject-specific methods for detecting recurrence of tumours based on an understanding of the clonal/subclonal mutation profile of the subject's tumour and detection of the mutations in their cell-free DNA (cfDNA), typically by multiplex PCR of tumour mutations such as single nucleotide variants (SNVs).
    Type: Application
    Filed: November 1, 2017
    Publication date: August 6, 2020
    Applicants: Natera, Inc., UCL BUSINESS PLC
    Inventors: Robert Charles SWANTON, Christopher ABBOSH
  • METHODS FOR LUNG CANCER DETECTION
    Publication number: 20190106751
    Abstract: The invention provides methods for detecting single nucleotide variants in lung cancer, especially stage 3a lung adenocarcinoma and lung squamous cell carcinoma. Additional methods and compositions, such as reaction mixtures and solid supports comprising clonal populations of nucleic acids, are provided.
    Type: Application
    Filed: April 17, 2017
    Publication date: April 11, 2019
    Applicants: Natera, Inc., UCL BUSINESS PLC
    Inventors: Bernhard ZIMMERMANN, Tudor Pompiliu CONSTANTIN, Raheleh SALARI, Huseyin Eser KIRKIZLAR, Robert Charles SWANTON, Mariam JAMAL-HANJANI, Christopher ABBOSH, Gareth WILSON