Abstract: The present invention relates to an oil-in-water emulsion comprising a glycopyrronium salt and an emulsifier system comprising at least one macrogol glycerol fatty acid ester, at least one glycerol fatty acid ester and at least one fatty alcohol. Moreover, the present invention relates to such an emulsion for use as a medicament, in particular for treating and preventing diseases in conjunction with excessive sweating. In addition the present invention relates to the non-therapeutic use of such an oil-in-water emulsion for topical application on the skin of a mammal in order to reduce sweating.

Abstract: The present invention relates to pharmaceutical and cosmetic formulations containing an extract of Echinacea and linoleic acid derivatives, particularly emulsions containing an extract of Echinacea and linoleic acid derivatives as an active agent combination, and the use of such formulations as medicines, medicinal products and/or cosmetics.

Abstract: The present invention relates to tripeptide compounds according to the general formula (1) and their use as a medicament, in particular as anti-inflammatory agents.

Abstract: The present invention relates to pharmaceutical and cosmetic formulations containing an extract of Echinacea and linoleic acid derivatives, particularly emulsions containing an extract of Echinacea and linoleic acid derivatives as an active agent combination, and the use of such formulations as medicines, medicinal products and/or cosmetics.

Abstract: The invention relates to Lysyl-Prolyl-Threonine lyophilized formulations, in particular to L-Lysyl-D-Prolyl-L-Threonine lyophilized formulations, that are stable in storage, and to a process for preparing the lyophilized formulations. Moreover, the invention relates to pharmaceutical and cosmetic compositions comprising the lyophilized formulations, that are used in the therapeutic and/or prophylactic treatment, diagnosis and/or therapy of pain-related diseases, pruritus-related diseases, inflammatory diseases, and/or other diseases in a mammal.

Abstract: The present invention relates to tripeptide compounds according to the general formula (1) and their use as a medicament, in particular as anti-inflammatory agents.

Abstract: The present invention relates to tripeptide compounds according to the general formula (1) and their use as a medicament, in particular as anti-inflammatory agents.

Abstract: The present invention relates to a water-in-oil emulsion and its use as a skin care product, in particular as a cosmetic and as a (dermatologic) medicament for aged skin. The emulsion contains a disperse/internal aqueous phase comprising an ?-hydroxy-C2-C6-carboxylic acid, a continuous/external oil phase and an emulsifier system, comprising polyglyceryl-3-polyricinoleate, sorbitan oleate and sucrose polystearate, wherein the emulsion has a pH of 1 to 5.

Abstract: The present invention relates to tripeptide compounds according to the general formula (1) and their use as a medicament, in particular as anti-inflammatory agents.

Abstract: The present invention relates to a novel class of 1,3-benzoxazol-2(3H)-ones and their use as a medicament, preferably as a dermatologic agent, and as a cosmetic. These novel compounds are particularly useful in treating and/or preventing inflammation, irritation, itching, pruritus, pain, oedema and/or pro-allergic or allergic conditions in a patient. Usually they are topically applied to the skin or mucosa in the form of a pharmaceutical or cosmetic composition comprising the compound and a pharmaceutically and/or cosmetically acceptable carrier.

Abstract: The use of eprotirome in the prevention and/or treatment of hair disorders is herein disclosed.

Abstract: The invention relates to amphotheric surfactants for use in preventing and/or treating vaginal infections, in particular for preventing and treating pathogenic vaginal biofilms in vaginal infections, as well as to pharmaceutical compositions containing the amphoteric surfactants as active ingredients.

Abstract: Disclosed is a system and method for improving the linearity of a clock and data recovery (CDR) circuit. In one embodiment, a data stream is received, and the phase of a clock signal is adjusted using two interpolators. The phase of the output signal of the second interpolator is adjusted simultaneously with, and complementary to, adjusting the phase of the first interpolator. The first interpolator's output signal is injected into a first delay cell in a delay loop having a plurality of delay cells, and the output of the second interpolator is inactivated. When the maximum phase of the first interpolator's output signal is reached, the second interpolator's output signal is injected into another one of the delay cells, and the first interpolator's output signal is inactivated. The data stream is then recovered using the output of the delay loop as a clock signal.

Abstract: In described embodiments, a communication system employing, for example, clock and data recovery (CDR) detects and applies correction for DC offset in an input data stream signal, termed as “DC offset calibration”. DC offset calibration applies static calibration for DC offset in input circuits, such as an input amplifier and detection latches, without input data, and applies statistical calibration for DC offset during operation with an input data stream to correct for dynamic shifts in DC level. Such DC offset calibration employs data eye measurements of the input data stream for detection of DC offset, and applies an opposite DC offset to maintain a relatively balanced data eye during live traffic.

Abstract: In described embodiments, a communication system employing, for example, clock and data recovery (CDR) detects and applies correction for DC offset in an input data stream signal, termed as “DC offset calibration”. DC offset calibration applies static calibration for DC offset in input circuits, such as an input amplifier and detection latches, without input data, and applies statistical calibration for DC offset during operation with an input data stream to correct for dynamic shifts in DC level. Such DC offset calibration employs data eye measurements of the input data stream for detection of DC offset, and applies an opposite DC offset to maintain a relatively balanced data eye during live traffic.

Abstract: Disclosed is a system and method for improving the linearity of a clock and data recovery (CDR) circuit. In one embodiment, a data stream is received, and the phase of a clock signal is adjusted using two interpolators. The phase of the output signal of the second interpolator is adjusted simultaneously with, and complementary to, adjusting the phase of the first interpolator. The first interpolator's output signal is injected into a first delay cell in a delay loop having a plurality of delay cells, and the output of the second interpolator is inactivated. When the maximum phase of the first interpolator's output signal is reached, the second interpolator's output signal is injected into another one of the delay cells, and the first interpolator's output signal is inactivated. The data stream is then recovered using the output of the delay loop as a clock signal.

Abstract: Disclosed is a system and method for improving the linearity of a clock and data recovery (CDR) circuit. In one embodiment, a data stream is received, and the phase of a clock signal is adjusted using two interpolators. The phase of the output signal of the second interpolator is adjusted simultaneously with, and complementary to, adjusting the phase of the first interpolator. The first interpolator's output signal is injected into a first delay cell in a delay loop having a plurality of delay cells, and the output of the second interpolator is inactivated. When the maximum phase of the first interpolator's output signal is reached, the second interpolator's output signal is injected into another one of the delay cells, and the first interpolator's output signal is inactivated. The data stream is then recovered using the output of the delay loop as a clock signal.

Abstract: Methods and apparatus are provided for determining a position of an offset latch employed for decision-feedback equalization. The position of an offset latch is determined by obtaining a plurality of samples of a data eye associated with a signal, the data eye comprised of a plurality of trajectories for transitions out of a given binary state; determining an amplitude of at least two of the trajectories based on the samples; and determining a position of an offset latch based on the determined amplitudes. The initial position of the offset latch can be placed, for example, approximately in the middle of the determined amplitudes for at least two of the trajectories. The initial position of the offset latch can be optionally skewed by a predefined amount to improve the noise margin.

Abstract: Disclosed is a system and method for improving the linearity of a clock and data recovery (CDR) circuit. A data stream is received and the phase of a clock signal is adjusted using two interpolators. The data stream is then recovered using the clock signal.

Abstract: Methods and apparatus are provided for controlling at least one of a rise time and a fall time of a signal. A plurality of time shifted clock signals are generated; and a received data signal is sampled using a plurality of parallel data paths, where each of the data paths are controlled by a corresponding one of the plurality of time shifted clock signals. The plurality of time shifted clock signals can be generated, for example, by at least one delay element. The plurality of parallel data paths can be substantially identical and comprise, for example, at least one latch or at least one flip flop. Compensation can optionally be provided for variations in, for example, process corner, supply voltage, aging and operating temperature.