Abstract: The present invention is directed to compounds of formula I The compounds are considered useful for the treatment of diseases associated with LRRK2 such as Parkinson's disease.

Abstract: This disclosure relates generally to jets for spas and, more specifically, to jets that can have more than one jet hydrotherapy spray mode. The jet can include a selectively rotatable jet head, the jet head having a first jet spray mode and a second jet spray mode. The jet head includes a valve, the valve having a first water inlet and a second water inlet, the valve further comprising a first air channel and a second air channel. The valve is rotatable from a first jet spray mode position in which a water intake is in fluid communication with the first water inlet and an air intake is in fluid communication with the first air channel, to a second jet spray mode position in which the water intake is in fluid communication with the second water inlet and the air intake is in fluid communication with the second air channel.

Abstract: Systems and methods for advertisement-based vehicle matching and routing. For example, a computer-implemented method includes obtaining data associated with a vehicle service request. The data associated with the vehicle service request is indicative of a pick-up location and a destination location associated with the vehicle service request. The method includes determining, from among a plurality of candidate vehicles, a selected vehicle for the vehicle service request based on the data indicative of the vehicle service request, candidate advertisement content items, and candidate routes for the plurality of candidate vehicles. The method includes communicating data that initiates display of a selected advertisement content item by a display device positioned on an exterior of the selected vehicle. The method includes communicating data indicative of route information to a computing device associated with the selected vehicle. The route information includes a selected route to the pick-up location.

Abstract: Systems and methods for displaying corresponding content for vehicle services using a distributed set of electronic devices are provided. For example, a computer-implemented method includes obtaining data associated with a vehicle service instance. The vehicle service instance is associated with a request for a vehicle service for a user. The method includes determining, based on the data associated with the vehicle service instance, a first advertisement content item for a display device positioned on an exterior of a vehicle assigned to the vehicle service instance and a second advertisement content item for a user device associated with the vehicle service instance. The method includes communicating data that initiates the display of the first advertisement content item for the display device positioned on the exterior of the vehicle and data that initiates the display of the second advertisement content item for the user device.

Abstract: This disclosure relates generally to jets for spas and, more specifically, to jets that can be adjusted laterally along a width of the proximal end of the jet housing. The angular adjustment of the proximal outlet of the jet may be at least 30°. In some embodiments, the jet assembly includes a housing with a distal inlet at a distal end of the housing and a proximal outlet at a proximal end of the housing, the proximal outlet laterally adjustable along a width of the proximal end of the housing, with the proximal outlet maintaining a constant depth with respect to the proximal end of the housing as the proximal outlet is laterally adjusted along the width of the proximal end of the housing.

Abstract: Disclosed is a robot apparatus with a capable and highly maneuverable drive system incorporating two differential swerve drive pods. The robot apparatus further includes a claw mechanism for grasping an object, a passthrough mechanism for moving the object horizontally and a lift mechanism for moving the object vertically. The robot apparatus allows for rapid manipulation and movement of objects such as cones.

Abstract: A method of assessing a membrane, including calculating fluid dynamic characteristics of at least one of a membrane and a material to be passed through the membrane, where the material comprises particles; obtaining characteristic of at least one force acting on the particles of the material to be passed through the membrane due to the interaction between the particles and the membrane, the at least one force being an intermolecular force; combining the calculated fluid dynamic characteristic and the obtained characteristics to assess the flow of the material through the membrane; and optimizing at least one characteristics of the membrane in relation to the material. The membrane includes a plurality of rows and a plurality of teardrop structures arranged in the plurality of rows. The teardrop structures in each row are arranged at substantially the same angle with respect to an anticipated direction of flow through the membrane.

Abstract: The present invention is directed to compounds of formula IIa These compounds are considered useful for the treatment of diseases associated with leucine-rich repeat kinase 2 (LRRK2) such as Parkinson's disease. Furthermore, the invention relates to pharmaceutical compositions comprising said compounds.

Abstract: In an aspect, an apparatus for procedural training is presented. An apparatus includes at least a processor and a memory communicatively connected to at least a processor. A memory contains instructions configuring at least a processor to receive optical data from a sensor comprising a machine vision system in electronic communication with the at least a processor, wherein the machine vision system is configured to identify at least one object within optical data. At least a processor is configured to determine a procedural performance parameter as a function of optical data wherein determining the procedural performance parameter comprises classifying the at least one object within optical data to an optical data category using an optical data classifier. At least a processor is configured to compare a procedural performance parameter to a procedural performance threshold. At least a processor is configured to display procedural training feedback through a display unit as a function of a comparison.

Abstract: An apparatus and method for an inspection apparatus for inspecting a component. The inspection apparatus including a robotic arm. A micro-XRF instrument having an instrument head coupled to the robotic arm. A seat supporting the component within a scanning area during inspection; and a computer in communication with the robotic arm and the micro-XRF instrument.

Abstract: In an aspect, an apparatus for procedural training is presented. An apparatus includes at least a processor and a memory communicatively connected to at least a processor. A memory contains instructions configuring at least a processor to receive optical data from a sensor in electronic communication with the at least a processor. At least a processor is configured to determine a procedural performance parameter as a function of optical data. At least a processor is configured to compare a procedural performance parameter to a procedural performance threshold. At least a processor is configured to display procedural training feedback through a display unit as a function of a comparison.

Abstract: Systems and methods for displaying corresponding content for vehicle services using a distributed set of electronic devices are provided. For example, a computer-implemented method includes obtaining data associated with a vehicle service instance. The vehicle service instance is associated with a request for a vehicle service for a user. The method includes determining, based on the data associated with the vehicle service instance, a first advertisement content item for a display device positioned on an exterior of a vehicle assigned to the vehicle service instance and a second advertisement content item for a user device associated with the vehicle service instance. The method includes communicating data that initiates the display of the first advertisement content item for the display device positioned on the exterior of the vehicle and data that initiates the display of the second advertisement content item for the user device.

Abstract: Systems and methods for advertisement-based vehicle matching and routing. For example, a computer-implemented method includes obtaining data associated with a vehicle service request. The data associated with the vehicle service request is indicative of a pick-up location and a destination location associated with the vehicle service request. The method includes determining, from among a plurality of candidate vehicles, a selected vehicle for the vehicle service request based on the data indicative of the vehicle service request, candidate advertisement content items, and candidate routes for the plurality of candidate vehicles. The method includes communicating data that initiates display of a selected advertisement content item by a display device positioned on an exterior of the selected vehicle. The method includes communicating data indicative of route information to a computing device associated with the selected vehicle. The route information includes a selected route to the pick-up location.

Abstract: Systems and methods for displaying corresponding content for vehicle services using a distributed set of electronic devices are provided. For example, a computer-implemented method includes obtaining data associated with a vehicle service instance. The vehicle service instance is associated with a request for a vehicle service for a user. The method includes determining, based on the data associated with the vehicle service instance, a first advertisement content item for a display device positioned on an exterior of a vehicle assigned to the vehicle service instance and a second advertisement content item for a user device associated with the vehicle service instance. The method includes communicating data that initiates the display of the first advertisement content item for the display device positioned on the exterior of the vehicle and data that initiates the display of the second advertisement content item for the user device.

Abstract: Systems and methods for advertisement-based vehicle matching a routing. For example, a computer-implemented method includes obtaining data associated with a vehicle that is online with a service entity associated with providing vehicle services. The method includes obtaining data associated with a vehicle that is online with a service entity associated with providing one or more vehicle services. The method includes determining that the vehicle is not currently associated with a vehicle service instance for performing the vehicle services and determining a selected advertisement content item for the vehicle. The method includes determining a selected route for the vehicle based on the selected advertisement content item. The method includes communicating data that initiates display of the selected advertisement content item via a display device positioned on an exterior of the vehicle and data indicative of route information to a computing device associated with the vehicle.

Abstract: In an aspect, an apparatus for procedural training is presented. An apparatus includes at least a processor and a memory communicatively connected to at least a processor. A memory contains instructions configuring at least a processor to receive optical data from a sensor in electronic communication with the at least a processor. At least a processor is configured to determine a procedural performance parameter as a function of optical data. At least a processor is configured to compare a procedural performance parameter to a procedural performance threshold. At least a processor is configured to display procedural training feedback through a display unit as a function of a comparison.

Abstract: A fixed-wing aerial vehicle includes: a fuselage with an on-board power supply; at least one fixed-wing or aerodynamic surface having at least one heater configured to be energized by the power supply, and having a superhydrophobic coating applied to at least a portion of the at least one fixed-wing or the aerodynamic surface that may be subject to icing; at least one capacitive sensor configured to detect ice formation on the at least one fixed-wing or aerodynamic surface; and a controller configured to selectively activate the at least one heater in response to detected ice formation.

Abstract: A fixed-wing aerial vehicle includes: a fuselage with an on-board power supply; at least one fixed-wing or aerodynamic surface having at least one heater configured to be energized by the power supply, and having a superhydrophobic coating applied to at least a portion of the at least one fixed-wing or the aerodynamic surface that may be subject to icing; at least one capacitive sensor configured to detect ice formation on the at least one fixed-wing or aerodynamic surface; and a controller configured to selectively activate the at least one heater in response to detected ice formation.

Abstract: A bag support system is designed to universally support plastic shopping bags with integrated loop handles in an upright and open position for re-use as trash bags or receptacles to store and/or sort other materials or components.