Abstract: A heating system is provided. The heating system includes a heat pump to provide heat. The heating system includes a circuit of heat transfer fluid to transfer heat to or from the heat pump. The heating system includes a space heating system configured to transfer heat from the heat transfer fluid to an environment. The heating system includes a water heating system comprising a water tank for storing hot water to be provided to a user, a cold water inlet, a hot water outlet for drawing off hot water for supply to a user, and a heat exchanger configured to exchange heat between the heat transfer fluid and water from the cold water inlet. The heating system includes a means of sensing a tank status, the tank status being indicative of a quantity of thermal energy stored in the tank. The heating system includes a controller adapted to control the transfer of heat to and from the tank in dependence on the tank status.

Abstract: Collecting and distributing information related to recent content publication activity of an instant messaging (IM) user provides other users in a network with timely, relevant information about people known to the user or within the same social network. A user participating in a social network can quickly and efficiently perceive new information related to other users (referred to as co-users) in a social network by reviewing the co-users' recent content publication activity. A user may be made able to do so without requiring the co-user to send a communication directly to the user regarding the new facts or new content, and also without requiring the user to actively browse or request information about the co-user.

Abstract: A surgical instrument system includes a main body having a handle and a drive assembly. The drive assembly includes a plurality of gears and rotation transfer mechanisms for translating the movements of the handle into a mechanical force. A surgical tool having a tool body, an elongated shaft and an effector assembly is removably engaged to the main body of the system. The tool body houses a transfer gear assembly for engaging the drive assembly. A plurality of control wires extends from the transfer gear assembly to the effector assembly. The effector assembly includes a frame member having a pair of arms positioned along the distal end. The arms functioning to selectively open, close and move omnidirectionally based on an input of the handle.

Abstract: Generally, a blood plasma immunomodulating agent rebalancing system. In particular, a blood plasma sTNFR and cytokine rebalancing system and methods of rebalancing sTNFR and cytokines in the blood plasma of a subject during plasmapheresis.

Abstract: Collecting and distributing information related to recent content publication activity of an instant messaging (IM) user provides other users in a network with timely, relevant information about people known to the user or within the same social network. A user participating in a social network can quickly and efficiently perceive new information related to other users (referred to as co-users) in a social network by reviewing the co-users' recent content publication activity. A user may be made able to do so without requiring the co-user to send a communication directly to the user regarding the new facts or new content, and also without requiring the user to actively browse or request information about the co-user.

Abstract: A surgical instrument system includes a main body having a handle and a drive assembly. The drive assembly includes a plurality of gears and rotation transfer mechanisms for translating the movements of the handle into a mechanical force. A surgical tool having a tool body, an elongated shaft and an effector assembly is removably engaged to the main body of the system. The tool body houses a transfer gear assembly for engaging the drive assembly. A plurality of control wires extends from the transfer gear assembly to the effector assembly. The effector assembly includes a frame member having a pair of arms positioned along the distal end. The arms functioning to selectively open, close and move omnidirectionally based on an input of the handle.

Abstract: Collecting and distributing information related to recent content publication activity of an instant messaging (IM) user provides other users in a network with timely, relevant information about people known to the user or within the same social network. A user participating in a social network can quickly and efficiently perceive new information related to other users (referred to as co-users) in a social network by reviewing the co-users' recent content publication activity. A user may be made able to do so without requiring the co-user to send a communication directly to the user regarding the new facts or new content, and also without requiring the user to actively browse or request information about the co-user.

Abstract: Collecting and distributing information related to recent content publication activity of an instant messaging (IM) user provides other users in a network with timely, relevant information about people known to the user or within the same social network. A user participating in a social network can quickly and efficiently perceive new information related to other users (referred to as co-users) in a social network by reviewing the co-users' recent content publication activity. A user may be made able to do so without requiring the co-user to send a communication directly to the user regarding the new facts or new content, and also without requiring the user to actively browse or request information about the co-user.

Abstract: This invention relates to sealing HVAC ductwork along its joints in order to reduce air leakage. The ductwork can be sealed by the combination of a gasket and mechanical locking mechanism.

Abstract: Collecting and distributing information related to recent content publication activity of an instant messaging (IM) user provides other users in a network with timely, relevant information about people known to the user or within the same social network. A user participating in a social network can quickly and efficiently perceive new information related to other users (referred to as co-users) in a social network by reviewing the co-users' recent content publication activity. A user may be made able to do so without requiring the co-user to send a communication directly to the user regarding the new facts or new content, and also without requiring the user to actively browse or request information about the co-user.

Abstract: This invention relates to sealing HVAC ductwork along its joints in order to reduce air leakage. The ductwork can be sealed by the combination of a gasket and mechanical locking mechanism.

Abstract: Collecting and distributing information related to recent content publication activity of an instant messaging (IM) user provides other users in a network with timely, relevant information about people known to the user or within the same social network. A user participating in a social network can quickly and efficiently perceive new information related to other users (referred to as co-users) in a social network by reviewing the co-users' recent content publication activity. A user may be made able to do so without requiring the co-user to send a communication directly to the user regarding the new facts or new content, and also without requiring the user to actively browse or request information about the co-user.

Abstract: Collecting and distributing information related to recent content publication activity of an instant messaging (IM) user provides other users in a network with timely, relevant information about people known to the user or within the same social network. A user participating in a social network can quickly and efficiently perceive new information related to other users (referred to as co-users) in a social network by reviewing the co-users' recent content publication activity. A user may be made able to do so without requiring the co-user to send a communication directly to the user regarding the new facts or new content, and also without requiring the user to actively browse or request information about the co-user.

Abstract: Methods of NAD-dependent of at least one lysine residue in an acetylated protein are disclosed. The methods include combining the acetylated protein with an isolated Sir2 protein or fragment that includes a core domain of the Sir2 protein. The Sir2 protein or fragment of the Sir2 protein can include a human Sir2 protein or a fragment of a human Sir2 protein.

Abstract: Methods of identifying agents which alter the NAD-dependent deacetylation activity of a Sir2 protein or a fragment of a Sir2 protein are disclosed. The acetylated protein can be a nuclear protein, such as a histone protein, or a cytoplasmic protein. The Sir2 protein employed in the methods can include at least a core domain of a Sir2 protein, such as a human Sir2 protein.

Abstract: Collecting and distributing information related to recent content publication activity of an instant messaging (IM) user provides other users in a network with timely, relevant information about people known to the user or within the same social network. A user participating in a social network can quickly and efficiently perceive new information related to other users (referred to as co-users) in a social network by reviewing the co-users' recent content publication activity. A user may be made able to do so without requiring the co-user to send a communication directly to the user regarding the new facts or new content, and also without requiring the user to actively browse or request information about the co-user.

Abstract: Collecting and distributing information related to recent content publication activity of an instant messaging (IM) user provides other users in a network with timely, relevant information about people known to the user or within the same social network. A user participating in a social network can quickly and efficiently perceive new information related to other users (referred to as co-users) in a social network by reviewing the co-users' recent content publication activity. A user may be made able to do so without requiring the co-user to send a communication directly to the user regarding the new facts or new content, and also without requiring the user to actively browse or request information about the co-user.

Abstract: Collecting and distributing information related to recent content publication activity of an instant messaging (IM) user provides other users in a network with timely, relevant information about people known to the user or within the same social network. A user participating in a social network can quickly and efficiently perceive new information related to other users (referred to as co-users) in a social network by reviewing the co-users' recent content publication activity. A user may be made able to do so without requiring the co-user to send a communication directly to the user regarding the new facts or new content, and also without requiring the user to actively browse or request information about the co-user.

Abstract: Collecting and distributing information related to recent content publication activity of an instant messaging (IM) user provides other users in a network with timely, relevant information about people known to the user or within the same social network. A user participating in a social network can quickly and efficiently perceive new information related to other users (referred to as co-users) in a social network by reviewing the co-users' recent content publication activity. A user may be made able to do so without requiring the co-user to send a communication directly to the user regarding the new facts or new content, and also without requiring the user to actively browse or request information about the co-user.

Abstract: Collecting and distributing information related to recent content publication activity of an instant messaging (IM) user provides other users in a network with timely, relevant information about people known to the user or within the same social network. A user participating in a social network can quickly and efficiently perceive new information related to other users (referred to as co-users) in a social network by reviewing the co-users' recent content publication activity. A user may be made able to do so without requiring the co-user to send a communication directly to the user regarding the new facts or new content, and also without requiring the user to actively browse or request information about the co-user.