Patents by Inventor Christopher B. FORD

Christopher B. FORD has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • USE OF IMMUNOTHERAPY AND MICROBIOME MODULATION TO TREAT CANCER
    Publication number: 20240148803
    Abstract: Provided herein are methods and compositions for the treatment of various types of cancers by modulating the microbiome to effect or enhance the efficacy of immunotherapy. Also provided herein are methods of determining a response to an immunotherapy by identifying if a subject has a favorable microbial profile. Further provided herein are methods of determining a donor whose feces are useful for fecal matter transfer.
    Type: Application
    Filed: February 18, 2022
    Publication date: May 9, 2024
    Applicant: Seres Therapeutics, Inc.
    Inventors: Christopher B. FORD, Elizabethh HALVORSEN, Christopher DESJARDINS, Kankana BARDHAN, Swarma Deepa PANDIAN
  • High-throughput dynamic reagent delivery system
    Patent number: 11904310
    Abstract: The present invention generally relates to a controlled fluidic device to develop spatially complex environments to enhance the rate of evolution in cell populations. The method further provides an enhanced understanding in the emergence, for example, drug resistance during cancer chemotherapy.
    Type: Grant
    Filed: October 28, 2016
    Date of Patent: February 20, 2024
    Assignees: The Broad Institute, Inc., Massachusetts Institute of Technology, President and Fellows of Harvard College, Dana-Farber Cancer Institute, Inc.
    Inventors: Anindita Basu, Christopher B. Ford, Aviv Regev, David A. Weitz, Asaf Rotem, Kevin Struhl
  • DESIGNED BACTERIAL COMPOSITIONS FOR TREATING GRAFT-VERSUS-HOST-DISEASE
    Publication number: 20240000859
    Abstract: Provided herein are bacterial compositions that are useful for treating and preventing complications and side effects associated with a disease or disorder, such as those associated with immune suppression, including infections and/or GvHD, for example, in HSCT subjects. The bacterial compositions disclosed herein are designed to exhibit one or more functional features that are useful for the treatment of such diseases and disorders.
    Type: Application
    Filed: November 24, 2021
    Publication date: January 4, 2024
    Applicant: Seres Therapeutics, Inc.
    Inventors: Matthew R. HENN, Edward J. O'BRIEN, Ambar PIÑA, Marin VULIC, Christopher B. FORD, Asuncion MARTINEZ, Divya BALASUBRAMANIAN, Elizabeth HALVORSEN, Karen KIESER, Mahmoud SALEH, Mary-Jane LOMBARDO, Sumon DATTA, Madhumitha NANDAKUMAR, Priyanka NARENDAR, Kankana BARDHAN
  • DESIGNED BACTERIAL COMPOSITIONS AND USES THEREOF
    Publication number: 20230125810
    Abstract: Provided herein are bacterial compositions that are useful for treating and preventing complications and side effects associated with a disease or disorder, such as those associated with dysbiosis of a gastrointestinal tract. The bacterial compositions disclosed herein are designed to exhibit one or more functional features that are useful for the treatment of such diseases and disorders.
    Type: Application
    Filed: November 25, 2020
    Publication date: April 27, 2023
    Applicant: Seres Therapeutics, Inc.
    Inventors: Asuncion MARTINEZ, Edward J. O'BRIEN, Sheri Lynn SIMMONS, David COOK, Matthew R. HENN, Christopher B. FORD, Divya BALASUBRAMANIAN, Ambar PIÑA, Liyang DIAO, Meghan CHAFEE, Marin VULIC, Madhumitha NANDAKUMAR, Sumon DATTA, Lata JAYARAMAN
  • Droplet-based method and apparatus for composite single-cell nucleic acid analysis
    Patent number: 11597964
    Abstract: The present invention generally relates to a combination of molecular barcoding and emulsion-based microfluidics to isolate, lyse, barcode, and prepare nucleic acids from individual cells in a high-throughput manner.
    Type: Grant
    Filed: March 8, 2017
    Date of Patent: March 7, 2023
    Assignees: The Broad Institute, Inc., Massachusetts Institute of Technology, President and Fellows of Harvard College
    Inventors: Aviv Regev, Evan Zane Macosko, Steven Andrew McCarroll, Alexander K. Shalek, Anindita Basu, Christopher B. Ford, Hongkun Park, David A. Weitz
  • Droplet-based method and apparatus for composite single-cell nucleic acid analysis
    Patent number: 11566279
    Abstract: The present invention generally relates to a combination of molecular barcoding and emulsion-based microfluidics to isolate, lyse, barcode, and prepare nucleic acids from individual cells in a high-throughput manner.
    Type: Grant
    Filed: January 9, 2019
    Date of Patent: January 31, 2023
    Assignees: The Broad Institute, Inc., Massachusetts Institute of Technology, President and Fellows of Harvard College
    Inventors: Aviv Regev, Evan Zane Macosko, Steven Andrew McCarroll, Alexander K. Shalek, Anindita Basu, Christopher B. Ford, Hongkun Park, David A. Weitz
  • DESIGNED BACTERIAL COMPOSITIONS AND USES THEREOF
    Publication number: 20210196766
    Abstract: Our client, Seres Therapeutics, has asked us to file a new provisional application related to bacterial compositions and the use of such compositions for the treatment of inflammatory bowel disease.
    Type: Application
    Filed: May 24, 2019
    Publication date: July 1, 2021
    Applicant: Seres Therapeutics, Inc.
    Inventors: Asuncion MARTINEZ, Edward J. O'BRIEN, Sheri Lynn SIMMONS, David COOK, Matthew R. HENN, Christopher B. FORD, Divya BALASUBRAMANIAN, Ambar PIÑA, Liyang DIAO, Meghan CHAFEE, Marin VULIC, Madhumitha NANDAKUMAR, Sumon DATTA, Latta JAYARAMAN
  • Droplet-Based Method And Apparatus For Composite Single-Cell Nucleic Acid Analysis
    Publication number: 20190127782
    Abstract: The present invention generally relates to a combination of molecular barcoding and emulsion-based microfluidics to isolate, lyse, barcode, and prepare nucleic acids from individual cells in a high-throughput manner.
    Type: Application
    Filed: January 9, 2019
    Publication date: May 2, 2019
    Inventors: Aviv REGEV, Evan Zane MACOSKO, Steven Andrew MCCARROLL, Alexander K. SHALEK, Anindita BASU, Christopher B. FORD, Hongkun PARK, David A. WEITZ
  • HIGH-THROUGHPUT DYNAMIC REAGENT DELIVERY SYSTEM
    Publication number: 20180311669
    Abstract: The present invention generally relates to a controlled fluidic device to develop spatially complex environments to enhance the rate of evolution in cell populations. The method further provides an enhanced understanding in the emergence, for example, drug resistance during cancer chemotherapy.
    Type: Application
    Filed: October 28, 2016
    Publication date: November 1, 2018
    Applicants: THE BROAD INSTITUTE, INC., MASSACHUSETTS INSTITUTE OF TECHNOLOGY, PRESIDENT AND FELLOWS OF HARVARD COLLEGE, DANA-FARBER CANCER INSTITUTE, INC.
    Inventors: Anindita BASU, Christopher B. FORD, Aviv REGEV, David A. WEITZ, Asaf ROTEM, Kevin STRUHL
  • Droplet-Based Method And Apparatus For Composite Single-Cell Nucleic Acid Analysis
    Publication number: 20180030515
    Abstract: The present invention generally relates to a combination of molecular barcoding and emulsion-based microfluidics to isolate, lyse, barcode, and prepare nucleic acids from individual cells in a high-throughput manner.
    Type: Application
    Filed: March 8, 2017
    Publication date: February 1, 2018
    Inventors: Aviv Regev, Evan Zane MACOSKO, Steven Andrew MCCARROLL, Alexander K. SHALEK, Anindita BASU, Christopher B. FORD, Hongkun PARK, David A. WEITZ