Abstract: Organs-on-chips are microfluidic devices for culturing living cells in micrometer sized chambers in order to model physiological functions of tissues and organs. Engineered patterning and continuous fluid flow in these devices has allowed culturing of intestinal cells bearing physiologically relevant features and sustained exposure to bacteria while maintaining cellular viability, thereby allowing study of inflammatory bowl diseases. However, existing intestinal cells do not possess all physiologically relevant subtypes, do not possess the repertoire of genetic variations, or allow for study of other important cellular actors such as immune cells. Use of iPSC-derived epithelium, including IBD patient-specific cells, allows for superior disease modeling by capturing the multi-faceted nature of the disease.

Abstract: A method at an asset tracking device, the method including activating a receiver at the asset tracking device; obtaining an intelligent transportation system message using the receiver; determining a position from the intelligent transportation system message; and reporting the determined position to a remote server.

Abstract: A cleaning device for cleaning a dispensing nozzle assembly of a beverage dispenser is disclosed. The dispensing nozzle assembly may include a macro-ingredient/diluent outlet and a number of micro-ingredient outlets surrounding the macro-ingredient/diluent outlet. The cleaning device may include a handle, a head end rotatably attached to the handle, a guidance protrusion extending from the head end, a first set of bristles extending from the head end and surrounding the guidance protrusion, and a second set of bristles extending from the head end adjacent to the first set of bristles.

Abstract: Embodiments are directed to a database configured to store digital versions of physical or electronic items received at a controlled-environment facility. Each of the digital versions associated with a unique identifier. A digital network portal is configured to provide remote access to the database. A production system is configured to create physical or electronic copies of selected ones of the stored digital versions. The physical or electronic copy comprises an image of the original physical or electronic item and a two-dimensional barcode. The two-dimensional barcode comprises a network address for the digital network portal and the unique identifier. The two-dimensional barcode may comprise a Quick Response (QR) code.

Abstract: Techniques of automated framing for use in the construction of building structures are described. Examples of such structures includes walls, wall panels, roofs, and the like. In one scenario, a robotic automated framing system assists with construction of a building structure. The robotic automated framing system can analyze an architectural plan and determine a project, based at least in part, on the architectural plan. The robotic automated framing system can also schedule a robot to perform the project, and cause the robot to perform at least some of the project.

Abstract: Faster, less computational intense, and more robust techniques to optimize velocity of robots or portions thereof without violating constraints on acceleration and jerk (derivative of acceleration with respect to time) are described. A nonlinear problem of optimizing velocity without violating acceleration constraints is linearized, and produces acceleration constrained velocity estimates. A nonlinear problem of optimizing velocity without violating jerk constraints in linearized, and produces jerk constrained velocity estimates, and may be feed by the acceleration constrained velocity estimates. Configuration and timing may be generated and provided, e.g., as vectors, to control operation of a robot, robotic appendage or other structure.

Abstract: Proactive multiple controlled-environment facility investigative data aggregation and analysis systems and methods may accept setup of alerts, each alert associated with particular data related to electronic communications, and each alert to be directed to at least one person not associated with the controlled-environment facility in which the communication originated, in which a particular resident associated with the electronic communication resides, and/or the like. Captured data related to electronic communications associated with each of a plurality of residents is received and/or retrieved and the at least one person not associated with the controlled-environment facility is alerted when the particular data related to electronic communications is received or retrieved with respect to a particular electronic communication.

Abstract: A method for fabricating a ceramic matrix composite component having a deltoid region is provided. The method includes providing a porous ceramic preform. The porous ceramic preform includes a layer-to-layer weave of ceramic fibers that forms a modified layer-to-layer woven core and at least one 2-dimensional layer of ceramic fibers that is disposed adjacent to the modified layer-to-layer woven core. The porous ceramic preform is formed into a ceramic matrix composite body having the deltoid region such that the modified layer-to-layer woven core extends through the deltoid region.

Abstract: A gas turbine engine may comprise a blade track and a method of making the same. The blade track may be constructed of ceramic matrix composite components including main body members and joints.

Abstract: Faster, less computational intense, and more robust techniques to optimize velocity of robots or portions thereof without violating constraints on acceleration and jerk (derivative of acceleration with respect to time) are described. A nonlinear problem of optimizing velocity without violating acceleration constraints is linearized, and produces acceleration constrained velocity estimates. A nonlinear problem of optimizing velocity without violating jerk constraints in linearized, and produces jerk constrained velocity estimates, and may be feed by the acceleration constrained velocity estimates. Configuration and timing may be generated and provided, e.g., as vectors, to control operation of a robot, robotic appendage or other structure.

Abstract: Methods and systems for processing audio signals include receiving, via an application displayed at a client computing device, an audio signal and a user control input for controlling an audio processing effect of the audio signal. The method may comprise sending the audio signal and the user control input to an audio server and then relaying the audio signal through the audio server to an input of an audio processing device. The method may also comprise controlling a setting on the audio processing device through a hardware controller based on the user control input, and returning a processed version of the audio signal from the audio processing device to the client computing device. The method may comprise adding an identifying signal between samples of an unprocessed version of the audio signal and initiating playback based on the identifying signal.

Abstract: A multi-piece disk for use in a turbine of a gas turbine engine. The multi-piece disk includes a fore disk segment and an aft disk segment coupled with the fore disk segment for movement with the fore disk segment. The fore disk segment and the aft disk segment are formed to define slots that extend through the disk segments and are configured to receive turbine blades therein.

Abstract: Disclosed are compositions of a fused filament fabrication (FFF) composite filament having embedded functional materials in a thermoplastic matrix. Methods of making the composite filaments are also disclosed. In one example, a FFF composite filament incorporates a MOF, in an amount greater than 10% by mass, dispersed in a matrix polymer. One example of a method of synthesizing FFF composite filaments involves mixing a suspension that has a MOF with a matrix polymer solution to yield a polymer-MOF mixture. The mixture is cast and dried into a solid composite material, which is formed a FFF composite filament having the MOF in an amount greater than 10% by mass.

Abstract: Methods and systems for processing audio signals include receiving, via an application displayed at a client computing device, an audio signal and a user control input for controlling an audio processing effect of the audio signal. The method may comprise sending the audio signal and the user control input to an audio server and then relaying the audio signal through the audio server to an input of an audio processing device. The method may also comprise controlling a setting on the audio processing device through a hardware controller based on the user control input, and returning a processed version of the audio signal from the audio processing device to the client computing device. The method may comprise adding an identifying signal between samples of an unprocessed version of the audio signal and initiating playback based on the identifying signal.

Abstract: Controlled-environment facility resident pattern electronic communication detection systems and methods may employ a controlled-environment facility secure communication platform, an investigative data aggregation and analysis system, and/or the like. Controlled-environment facility individual resident outgoing electronic communication velocity is monitored. The individual resident outgoing electronic communication velocity may be the number of electronic communications placed by a controlled-environment facility resident, to telephone numbers and/or electronic communication addresses over a period of time.

Abstract: A method of slurry infiltration and cleaning to fabricate a ceramic matrix composite (CMC) component with an internal cavity or bore comprises inserting a number of rods into a hollow portion of a porous fiber preform, thereby forming a rod arrangement substantially filling the hollow portion. Each of the rods has a low-friction surface comprising a coefficient of static friction of about 0.1 or less. The porous fiber preform is exposed to a slurry comprising particulate solids in a liquid carrier, and the slurry infiltrates the porous fiber preform. Some fraction of the particulate solids is deposited within interstices of the porous fiber preform to form an impregnated fiber preform, and another fraction of the particulate solids is deposited within the hollow portion as excess slurry. After slurry infiltration, the rods are withdrawn from the hollow portion, and at least some of the excess slurry is removed with the rods.

Abstract: A multi-piece disk for use in a turbine of a gas turbine engine. The multi-piece disk includes a fore disk segment and an aft disk segment coupled with the fore disk segment for movement with the fore disk segment. The fore disk segment and the aft disk segment are formed to define slots that extend through the disk segments and are configured to receive turbine blades therein.

Abstract: Disclosed are compositions of a fused filament fabrication (FFF) composite filament having embedded functional materials in a thermoplastic matrix. Methods of making the composite filaments are also disclosed. In one example, a FFF composite filament incorporates a MOF, in an amount greater than 10% by mass, dispersed in a matrix polymer. One example of a method of synthesizing FFF composite filaments involves mixing a suspension that has a MOF with a matrix polymer solution to yield a polymer-MOF mixture. The mixture is cast and dried into a solid composite material, which is formed a FFF composite filament having the MOF in an amount greater than 10% by mass.

Abstract: Compositions and processes are disclosed for forming hydrophobic coatings and lubricant-infused surface coatings. Coatings may be applied to various substrates without prior chemical or temperature treatment of the substrates and over large and irregular surfaces. Coatings are self-healing, anti-fouling, and have enhanced lifetimes.

Abstract: Methods and systems for processing audio signals include receiving, via an application displayed at a client computing device, an audio signal and a user control input for controlling an audio processing effect of the audio signal. The method may comprise sending the audio signal and the user control input to an audio server and then relaying the audio signal through the audio server to an input of an audio processing device. The method may also comprise controlling a setting on the audio processing device through a hardware controller based on the user control input, and returning a processed version of the audio signal from the audio processing device to the client computing device. The method may comprise adding an identifying signal between samples of an unprocessed version of the audio signal and initiating playback based on the identifying signal.