Patents by Inventor Christopher Barry Locke

Christopher Barry Locke has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 11691028
    Abstract: Methods of beam angle optimization for intensity modulated radiotherapy (IMRT) treatment include determining beam's eye view (BEV) regions and a BEV region connectivity manifold by evaluating dose response of each region of interest for each vertex in a delivery coordinate space (DCS). The information contained in the BEV regions and the BEV region connectivity manifold is used to guide an optimizer to find optimal field geometries in the IMRT treatment. To improve the visibility of insufficiently exposed voxels of planning target volumes (PTVs), a post-processing step may be performed to enlarge certain BEV regions, which are considered for exposing during treatment trajectory optimization.
    Type: Grant
    Filed: February 8, 2021
    Date of Patent: July 4, 2023
    Assignees: SIEMENS HEALTHINEERS INTERNATIONAL AG, THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY
    Inventors: Christopher Barry Locke, Santtu Ollila, Karl Kenneth Bush
  • Patent number: 11691027
    Abstract: Methods of treatment trajectory optimization for radiotherapy treatment of multiple targets include determining beam's eye view (BEV) regions and a BEV region connectivity manifold for each target group of a plurality of target groups separately. The information contained in the BEV regions and the BEV region connectivity manifolds for all target groups is used to guide an optimizer to find optimal treatment trajectories. To improve the visibility of insufficiently exposed voxels of planning target volumes (PTVs), a post-processing step may be performed to enlarge certain BEV regions, which are considered for exposing during treatment trajectory optimization.
    Type: Grant
    Filed: February 8, 2021
    Date of Patent: July 4, 2023
    Assignees: SIEMENS HEALTHINEERS INTERNATIONAL AG, THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY
    Inventors: Christopher Barry Locke, Santtu Ollila, Karl Kenneth Bush
  • Publication number: 20210178188
    Abstract: Methods of treatment trajectory optimization for radiotherapy treatment of multiple targets include determining beam's eye view (BEV) regions and a BEV region connectivity manifold for each target group of a plurality of target groups separately. The information contained in the BEV regions and the BEV region connectivity manifolds for all target groups is used to guide an optimizer to find optimal treatment trajectories. To improve the visibility of insufficiently exposed voxels of planning target volumes (PTVs), a post-processing step may be performed to enlarge certain BEV regions, which are considered for exposing during treatment trajectory optimization.
    Type: Application
    Filed: February 8, 2021
    Publication date: June 17, 2021
    Applicants: Varian Medical Systems International AG, The Board of Trustees of the Leland Stanford Junior University, Office of the General Counsel
    Inventors: Christopher Barry Locke, Santtu Ollila, Karl Kenneth Bush
  • Publication number: 20210178189
    Abstract: Methods of beam angle optimization for intensity modulated radiotherapy (IMRT) treatment include determining beam's eye view (BEV) regions and a BEV region connectivity manifold by evaluating dose response of each region of interest for each vertex in a delivery coordinate space (DCS). The information contained in the BEV regions and the BEV region connectivity manifold is used to guide an optimizer to find optimal field geometries in the IMRT treatment. To improve the visibility of insufficiently exposed voxels of planning target volumes (PTVs), a post-processing step may be performed to enlarge certain BEV regions, which are considered for exposing during treatment trajectory optimization.
    Type: Application
    Filed: February 8, 2021
    Publication date: June 17, 2021
    Applicants: Varian Medical Systems International AG, The Board of Trustees of the Leland Stanford Junior University, Office of the General Counsel
    Inventors: Christopher Barry Locke, Santtu Ollila, Karl Kenneth Bush
  • Patent number: 10946216
    Abstract: Methods of treatment trajectory optimization for radiotherapy treatment of multiple targets include determining beam's eye view (BEV) regions and a BEV region connectivity manifold for each target group of a plurality of target groups separately. The information contained in the BEV regions and the BEV region connectivity manifolds for all target groups is used to guide an optimizer to find optimal treatment trajectories. To improve the visibility of insufficiently exposed voxels of planning target volumes (PTVs), a post-processing step may be performed to enlarge certain BEV regions, which are considered for exposing during treatment trajectory optimization.
    Type: Grant
    Filed: December 28, 2018
    Date of Patent: March 16, 2021
    Assignees: Varian Medical Systems International AG, The Board of Trustees of the Leland Stanford Junior University, Office of the General Counsel
    Inventors: Christopher Barry Locke, Santtu Ollila, Karl Kenneth Bush
  • Patent number: 10946217
    Abstract: Methods of beam angle optimization for intensity modulated radiotherapy (IMRT) treatment include determining beam's eye view (BEV) regions and a BEV region connectivity manifold by evaluating dose response of each region of interest for each vertex in a delivery coordinate space (DCS). The information contained in the BEV regions and the BEV region connectivity manifold is used to guide an optimizer to find optimal field geometries in the IMRT treatment. To improve the visibility of insufficiently exposed voxels of planning target volumes (PTVs), a post-processing step may be performed to enlarge certain BEV regions, which are considered for exposing during treatment trajectory optimization.
    Type: Grant
    Filed: December 28, 2018
    Date of Patent: March 16, 2021
    Assignees: Varian Medical Systems International AG, The Board of Trustees of the Leland Stanford Junior University, Office of the General Counsel
    Inventors: Christopher Barry Locke, Santtu Ollila, Karl Kenneth Bush
  • Publication number: 20200206531
    Abstract: Methods of treatment trajectory optimization for radiotherapy treatment of multiple targets include determining beam's eye view (BEV) regions and a BEV region connectivity manifold for each target group of a plurality of target groups separately. The information contained in the BEV regions and the BEV region connectivity manifolds for all target groups is used to guide an optimizer to find optimal treatment trajectories. To improve the visibility of insufficiently exposed voxels of planning target volumes (PTVs), a post-processing step may be performed to enlarge certain BEV regions, which are considered for exposing during treatment trajectory optimization.
    Type: Application
    Filed: December 28, 2018
    Publication date: July 2, 2020
    Applicants: Varian Medical Systems International AG, The Board of Trustees of the Leland Stanford Junior University, Office of the General Counsel
    Inventors: Christopher Barry Locke, Santtu Ollila, Karl Kenneth Bush
  • Publication number: 20200101320
    Abstract: Methods of beam angle optimization for intensity modulated radiotherapy (IMRT) treatment include determining beam's eye view (BEV) regions and a BEV region connectivity manifold by evaluating dose response of each region of interest for each vertex in a delivery coordinate space (DCS). The information contained in the BEV regions and the BEV region connectivity manifold is used to guide an optimizer to find optimal field geometries in the IMRT treatment. To improve the visibility of insufficiently exposed voxels of planning target volumes (PTVs), a post-processing step may be performed to enlarge certain BEV regions, which are considered for exposing during treatment trajectory optimization.
    Type: Application
    Filed: December 28, 2018
    Publication date: April 2, 2020
    Applicants: Varian Medical Systems International AG, The Board of Trustees of the Leland Stanford Junior University, Office of the General Counsel
    Inventors: Christopher Barry Locke, Santtu Ollila, Karl Kenneth Bush