Patents by Inventor Christopher B. Eckman

Christopher B. Eckman has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Methods for making polymeric nanoparticle-polypeptide complex
    Patent number: 9636384
    Abstract: This document relates to methods and materials involved in delivering molecules to a mammal. For example, methods and materials for using nanoparticles to increase the half-life and the bioavailability of molecules administered to a mammal are provided.
    Type: Grant
    Filed: April 5, 2010
    Date of Patent: May 2, 2017
    Assignee: Mayo Foundation For Medical Education and Research
    Inventors: Christopher B. Eckman, Aimee R. Herdt
  • METHODS AND MATERIALS FOR DELIVERING MOLECULES
    Publication number: 20120040432
    Abstract: This document relates to methods and materials involved in delivering molecules to a mammal. For example, methods and materials for using nanoparticles to increase the half-life and the bioavailability of molecules administered to a mammal are provided.
    Type: Application
    Filed: April 5, 2010
    Publication date: February 16, 2012
    Applicant: MAYO FOUNDATION FOR MEDICAL EDUCATION AND RESEARCH
    Inventors: Christopher B. Eckman, Aimee R. Herdt
  • METHODS OF REDUCING BETA-AMYLOID POLYPEPTIDES
    Publication number: 20080299229
    Abstract: The invention features methods of reducing the level of a ?-amyloid (A?) polypeptide using an Cimicifuga extract. The invention also features methods of producing an active fraction from an extract of Cimicifuga. The invention further features a composition containing an active fraction of a Cimicifuga extract and an article of manufacture containing such a composition.
    Type: Application
    Filed: October 22, 2007
    Publication date: December 4, 2008
    Inventors: Christopher B. Eckman, Debra Yager, Sharie Haugabook, Adbul Fauq
  • Methods of reducing ?-amyloid polypeptides
    Patent number: 7300677
    Abstract: The invention features methods of reducing the level of a ?-amyloid (A?) polypeptide using an Cimicifuga extract. The invention also features methods of producing an active fraction from an extract of Cimicifuga. The invention further features a composition containing an active fraction of a Cimicifuga extract and an article of manufacture containing such a composition.
    Type: Grant
    Filed: September 30, 2005
    Date of Patent: November 27, 2007
    Assignee: Mayo Foundation for Medical Education and Research
    Inventors: Christopher B. Eckman, Debra Yager, Sharie Haugabook, Abdul Fauq
  • Methods of reducing beta-amyloid polypeptides
    Publication number: 20040071802
    Abstract: The invention features methods of reducing the level of a &bgr;-amyloid (A&bgr;) polypeptide using an Cimicifuga extract. The invention also features methods of producing an active fraction from an extract of Cimicifuga. The invention further features a composition containing an active fraction of a Cimicifuga extract and an article of manufacture containing such a composition.
    Type: Application
    Filed: October 8, 2003
    Publication date: April 15, 2004
    Applicant: Mayo Foundation for Medical Education and Research a Minnesota corporation
    Inventors: Christopher B. Eckman, Debra Yager, Sharie Haugabook, Abdul Fauq
  • Endothelin converting enzymes and the amyloid &bgr; peptide
    Patent number: 6699681
    Abstract: The invention describes catabolism of A&bgr; by endothelin converting enzymes (ECEs). Methods of identifying compounds that upregulate ECEs are provided by the invention. Further provided by the invention are methods of regulating A&bgr; catabolism in a cell and methods of decreasing the amount of A&bgr; in a cell. The invention discloses methods of diagnosing an individual with AD and methods of treating such an individual. The invention further discloses methods of identifying compounds that have anti-hypertension activity but do not cause an increase in the level of A&bgr;. Further, the invention provides mutant ECE nucleic acids and mutant ECE polypeptides.
    Type: Grant
    Filed: April 3, 2001
    Date of Patent: March 2, 2004
    Assignee: Mayo Foundation for Medical Education and Research
    Inventors: Christopher B. Eckman, Elizabeth A. Eckman
  • Methods of reducing &bgr;-amyloid polypeptides
    Patent number: 6649196
    Abstract: The invention features methods of reducing the level of a &bgr;-amyloid (A&bgr;) polypeptide using an Cimicifuga extract. The invention also features methods of producing an active fraction from an extract of Cimicifuga. The invention further features a composition containing an active fraction of a Cimicifuga extract and an article of manufacture containing such a composition.
    Type: Grant
    Filed: March 12, 2001
    Date of Patent: November 18, 2003
    Assignee: Mayo Foundation for Medical Education and Research
    Inventors: Christopher B. Eckman, Debra Yager, Sharie Haugabook, Abdul Fauq
  • Methods of reducing beta-amyloid polypeptides
    Publication number: 20020127290
    Abstract: The invention features methods of reducing the level of a &bgr;-amyloid (A&bgr;) polypeptide using an Cimicifuga extract. The invention also features methods of producing an active fraction from an extract of Cimicifuga. The invention further features a composition containing an active fraction of a Cimicifuga extract and an article of manufacture containing such a composition.
    Type: Application
    Filed: March 12, 2001
    Publication date: September 12, 2002
    Inventors: Christopher B. Eckman, Debra Yager, Sharie Haugabook, Abdul Fauq
  • Endothelin converting enzymes and the amyloid beta peptide
    Publication number: 20020091072
    Abstract: The invention describes catabolism of A&bgr; by endothelin converting enzymes (ECEs). Methods of identifying compounds that upregulate ECEs are provided by the invention. Further provided by the invention are methods of regulating A&bgr; catabolism in a cell and methods of decreasing the amount of A&bgr; in a cell. The invention discloses methods of diagnosing an individual with AD and methods of treating such an individual. The invention further discloses methods of identifying compounds that have anti-hypertension activity but do not cause an increase in the level of A&bgr;. Further, the invention provides mutant ECE nucleic acids and mutant ECE polypeptides.
    Type: Application
    Filed: April 3, 2001
    Publication date: July 11, 2002
    Inventors: Christopher B. Eckman, Elizabeth A. Eckman