Patents by Inventor Christopher Black
Christopher Black has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20080153750Abstract: The present invention provides a method of purifying diphtheria toxin comprising (1) fermenting a microorganism strain capable of producing diphtheria toxin using glucose as a carbon source, said method comprising adding glucose to a growing culture whereby the addition of glucose maintains microorganism growth effective to support diphtheria toxin production; and (2) purifying the diphtheria toxin from the culture by contacting a toxin containing preparation derived therefrom with an ion exchange matrix, eluting a fraction containing the toxin, applying the eluate to a hydrophobic matrix, and eluting a fraction containing the toxin.Type: ApplicationFiled: September 13, 2007Publication date: June 26, 2008Inventors: Henry Wolfe, Fahar Merchant, Rosemina Merchant, Christopher Black, Harry Storflor, Geir Stokke, Halldis Hellebust
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Publication number: 20080010045Abstract: An NSET method and system for modeling the behavior of a visitor to an e-commerce location are disclosed. The method of one embodiment of this invention comprises the steps of: obtaining one or more visitor characteristic values; developing a model of the visitor's behavior according to a nonlinear state estimation technique (NSET); and estimating a set of visitor behavior characteristic to model the visitor's behavior using the developed model. The method further comprises predicting the visitor's future behavior at the e-commerce location based on the set of behavior characteristic values and known statistical behavior characteristic values. The method of this invention can further comprise measuring a set of actual behavior values for a visitor based on the visitor's actual behavior at an e-commerce location, and comparing the set of estimated behavior characteristic values and the set of actual behavior values with at least one similarity operator.Type: ApplicationFiled: August 28, 2007Publication date: January 10, 2008Applicant: SmartSignal CorporationInventors: Christopher Black, J. Hines
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Patent number: 7273728Abstract: The present invention provides a method of purifying diphtheria toxin comprising (1) fermenting a microorganism strain capable of producing diphtheria toxin using glucose as a carbon source, the method comprising adding glucose to a growing culture whereby the addition of glucose maintains microorganism growth effective to support diphtheria toxin production; and (2) purifying the diphtheria toxin from the culture by contacting a toxin containing preparation derived therefrom with an ion exchange matrix, eluting a fraction containing the toxin, applying the eluate to a hydrophobic matrix, and eluting a fraction containing the toxin.Type: GrantFiled: August 15, 2005Date of Patent: September 25, 2007Assignee: GE Healthcare ASInventors: Henry Wolfe, Fahar Merchant, Rosemina Merchant, Christopher Black, Harry Storflor, Geir Stokke, Halldis Hellebust
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Publication number: 20070148380Abstract: The present invention relates to a paintball comprising a shell containing an inner filler composition. The shell comprises a mixture of gelatin and mineral oil; the inner filler composition comprises a mixture of starch, oil, an emulsifying agent and a spreading and surfacting agent. The shell further comprises a non-crystallizing polyhydric alcohol, glycerine, and water. The inner filler composition may further comprise a pigment. The non-crystallizing polyhydric alcohol may be sorbitol, the oil is Soya oil and the emulsifying agent is emulsifying wax. The spreading and surfacting agent may be Tween® 20 and the pigment may be TiO2.Type: ApplicationFiled: December 19, 2006Publication date: June 28, 2007Inventor: Christopher Black
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Publication number: 20060085850Abstract: A system and method for ensuring that machines having invalid or corrupt states are restricted from accessing host resources are provided. A quarantine agent (QA) located on a client machine acquires statements of health from a plurality of quarantine policy clients. The QA packages the statements and provides the package to a quarantine enforcement client (QEC). The QEC sends the package to a quarantine Health Certificate Server (HCS) with a request for a health certificate. If the client provided valid statements of health, the HCS grants the client health certificate that may be used in IPsec session negotiation.Type: ApplicationFiled: February 14, 2005Publication date: April 20, 2006Applicant: Microsoft CorporationInventors: Paul Mayfield, Christopher Black, Jesper Johansson, Karthik Murthy, Brian Swander
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Publication number: 20060035340Abstract: The present invention provides a method of purifying diphtheria toxin comprising (1) fermenting a microorganism strain capable of producing diphtheria toxin using glucose as a carbon source, said method comprising adding glucose to a growing culture whereby the addition of glucose maintains microorganism growth effective to support diphtheria toxin production; and (2) purifying the diphtheria toxin from the culture by contacting a toxin containing preparation derived therefrom with an ion exchange matrix, eluting a fraction containing the toxin, applying the eluate to a hydrophobic matrix, and eluting a fraction containing the toxin.Type: ApplicationFiled: August 15, 2005Publication date: February 16, 2006Inventors: Henry Wolfe, Fahar Merchant, Rosemina Merchant, Christopher Black, Harry Storflor, Geir Stokke, Halldis Hellebust
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Patent number: 6962803Abstract: The present invention provides a method of purifying diphtheria toxin comprising (1) fermenting a microorganism strain capable of producing diphtheria toxin using glucose as a carbon source, said method comprising adding glucose to a growing culture whereby the addition of glucose maintains microorganism growth effective to support diphtheria toxin production; and (2) purifying the diphtheria toxin from the culture by contacting a toxin containing preparation derived therefrom with an ion exchange matrix, eluting a fraction containing the toxin, applying the eluate to a hydrophobic matrix, and eluting a fraction containing the toxin.Type: GrantFiled: October 22, 2003Date of Patent: November 8, 2005Assignee: Amersham Health ASInventors: Henry Wolfe, Fahar Merchant, Rosemina Merchant, Christopher Black, Harry Storflor, Geir Stokke, Halldis Hellebust
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Patent number: 6927570Abstract: An apparatus is provided for quantitatively measuring samples whose amount or other characteristic quality is to be determined. The samples are arranged in a predefined pattern and are excited in a magnetic field. The magnetizations of the magnetic particles are thereby caused to oscillate at the excitation frequency in the manner of a dipole to create their own fields. These fields are inductively coupled to at least one substantially flat sensor such as sensing coils fabricated in a gradiometer configuration.Type: GrantFiled: July 22, 2003Date of Patent: August 9, 2005Assignee: Quantum Design, Inc.Inventors: Michael Bancroft Simmonds, Kurt Gordon Jensen, Jost Hermann Diederichs, Randall Christopher Black
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Publication number: 20040150396Abstract: An apparatus is provided for quantitatively measuring combinations of magnetic particles combined with analytes whose amount or other characteristic quality is to be determined. The magnetic particles are complexed with the analytes to be determined and are excited in a magnetic field. The magnetizations of the magnetic particles are thereby caused to oscillate at the excitation frequency in the manner of a dipole to create their own fields. These fields are inductively coupled to at least one sensor such as sensing coils fabricated in a gradiometer configuration. The output signals from the sensing coils are appropriately amplified and processed to provide useful output indications.Type: ApplicationFiled: July 22, 2003Publication date: August 5, 2004Inventors: Michael Bancroft Simmonds, Kurt Gordon Jensen, Jost Hermann Diederichs, Randall Christopher Black
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Publication number: 20040097779Abstract: Radioactive sources, preferably radioactive seeds, for use in brachytherapy comprising a radioisotope within a sealed biocompatible container, wherein at least one part of a surface of the container is roughened, shaped or otherwise treated so that it is no longer smooth. The surface treatment may enhance the ultrasound visibility of the source and/or reduce the tendency of the source to migrate once implanted in a patient's body. Preferred radioisotopes are palladium-103 and iodine-125.Type: ApplicationFiled: November 6, 2003Publication date: May 20, 2004Inventors: Gregory Mclntire, Robert Snow, Edward Bacon, Morten Eriksen, Auden Tornes, Geraldine Cooney, Virginia Ann Gates, Joel Cornacoff, Christopher Black
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Publication number: 20040087775Abstract: The present invention provides a method of purifying diphtheria toxin comprising (1) fermenting a microorganism strain capable of producing diphtheria toxin using glucose as a carbon source, said method comprising adding glucose to a growing culture whereby the addition of glucose maintains microorganism growth effective to support diphtheria toxin production; and (2) purifying the diphtheria toxin from the culture by contacting a toxin containing preparation derived therefrom with an ion exchange matrix, eluting a fraction containing the toxin, applying the eluate to a hydrophobic matrix, and eluting a fraction containing the toxin.Type: ApplicationFiled: October 22, 2003Publication date: May 6, 2004Inventors: Henry Wolfe, Fahar Merchant, Rosemina Merchant, Christopher Black, Harry Storflor, Geir Stokke, Halldis Hellebust
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Patent number: 6689043Abstract: Radioactive sources, preferably radioactive seeds, for use in brachytherapy comprising a radioisotope within a sealed biocompatible container, wherein at least one part of a surface of the container is roughened, shaped or otherwise treated so that it is no longer smooth. The surface treatment may enhance the ultrasound visibility of the source and/or reduce the tendency of the source to migrate once implanted in a patient's body. Preferred radioisotopes are palladium-103 and iodine-125.Type: GrantFiled: July 23, 2001Date of Patent: February 10, 2004Assignee: Amersham PLCInventors: Gregory McIntire, Robert Snow, Edward Bacon, Morten Eriksen, Auden Tornes, Geraldine Cooney, Christopher Black, Joel Cornacoff, Virginia Ann Gates
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Patent number: 6689871Abstract: The present invention provides a method of purifying diphtheria toxin comprising (1) fermenting a microorganism strain capable of producing diphtheria toxin using glucose as a carbon source, the method comprising adding glucose to a growing culture whereby the addition of glucose maintains microorganism growth effective to support diphtheria toxin production; and (2) purifying the diphtheria toxin from the culture by contacting a toxin containing preparation derived therefrom with an ion exchange matrix, eluting a fraction containing the toxin, applying the eluate to a hydrophobic matrix, and eluting a fraction containing the toxin.Type: GrantFiled: January 25, 2002Date of Patent: February 10, 2004Assignee: Amersham Health ASInventors: Henry Wolfe, Fahar Merchant, Rosemina Merchant, Christopher Black, Harry Storflor, Geir Stokke, Halldis Hellebust
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Patent number: 6632176Abstract: Radioactive sources, preferably radioactive seeds, for use in brachytherapy comprising a radioisotope within a sealed biocompatible container, wherein at least one part of a surface of the container is roughened, shaped or otherwise treated so that it is no longer smooth. The surface treatment may enhance the ultrasound visibility of the source and/or reduce the tendency of the source to migrate once implanted in a patient's body. Preferred radioisotopes are palladium-103 and iodine-125.Type: GrantFiled: May 17, 2001Date of Patent: October 14, 2003Assignee: Amersham PLCInventors: Gregory McIntire, Robert Snow, Edward Bacon, Morten Eriksen, Auden Tornes, Geraldine Cooney, Virginia Ann Gates, Joel Cornacoff, Christopher Black
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Publication number: 20030162960Abstract: The present invention provides novel compounds exemplified by pyrrolic nitrogens used as anion and neutral species recognition elements with an aromatic core as a signal group. Described are methods for the synthesis of various pyrrole aryl compounds as well as various applications for these compounds. Methods of use include the binding and detection of specific analytes in a mixture and, in some examples, the separation of the analyte from the mixture. Additional methods of use include the transport of therapeutic agents and the sensing of components, degradants, and impurities in foodstuffs.Type: ApplicationFiled: August 16, 2002Publication date: August 28, 2003Inventors: Jonathan Sessler, Bruno Andrioletti, Andrew Try, Christopher Black
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Patent number: 6597176Abstract: An apparatus is provided for quantitatively determining amounts and identities of substances whithin patterns of magnetic particles, such as within lateral flow membranes, microfludic systems, and the like. Magnetic particles are complexed with substances to be determined and are excited in an oscillating magnetic field. The magnetizations of the magnetic particles are thereby caused to oscillate at the excitation frequency to create their own fields. These fields are inductively coupled to at least one sensor such as sensing coils fabricated in a gradiometer configuration. The output signals from the sensing coils are appropriately amplified and processed to provide useful output indications.Type: GrantFiled: July 23, 2001Date of Patent: July 22, 2003Assignee: Quantum Design, Inc.Inventors: Michael Bancroft Simmonds, Kurt Gordon Jensen, Jost Hermann Diederichs, Randall Christopher Black
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Patent number: 6483303Abstract: An apparatus is provided for quantitatively measuring groups of magnetic particles. The particles are complexed with substances to be determined and are excited in a magnetic field. The magnetizations of the magnetic particles are thereby caused to oscillate at the excitation frequency in the manner of a dipole to create their own fields. These fields are inductively coupled to at least one sensor such as sensing coils fabricated in a gradiometer configuration. The output signals from the sensing coils are appropriately amplified and processed to provide useful output indications.Type: GrantFiled: July 23, 2001Date of Patent: November 19, 2002Assignee: Quantum Design, Inc.Inventors: Michael Bancroft Simmonds, Kurt Gordon Jensen, Jost Hermann Diederichs, Randall Christopher Black
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Patent number: 6482949Abstract: The present invention provides novel compounds exemplified by pyrrolic nitrogens used as anion and neutral species recognition elements with an aromatic core as a signal group. Described are methods for the synthesis of various pyrrole aryl compounds as well as various applications for these compounds. Methods of use include the binding and detection of specific analytes in a mixture and, in some examples, the separation of the analyte from the mixture. Additional methods of use include the transport of therapeutic agents and the sensing of components, degradants, and impurities in foodstuffs.Type: GrantFiled: May 26, 2000Date of Patent: November 19, 2002Inventors: Jonathan Sessler, Bruno Andrioletti, Andrew Carl Try, Christopher Black
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Patent number: 6437563Abstract: An apparatus is provided for quantitatively measuring combinations of magnetic particles combined with analytes whose amount or other characteristic quality is to be determined. The magnetic particles are complexed with the analytes to be determined and are excited in a magnetic field. The magnetizations of the magnetic particles are thereby caused to oscillate at the excitation frequency in the manner of a dipole to create their own fields. These fields are inductively coupled to at least one sensor such as sensing coils fabricated in a gradiometer configuration. The output signals from the sensing coils are appropriately amplified and processed to provide useful output indications.Type: GrantFiled: November 30, 1999Date of Patent: August 20, 2002Assignee: Quantum Design, Inc.Inventors: Michael Bancroft Simmonds, Kurt Gordon Jensen, Jost Hermann Diederichs, Randall Christopher Black
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Patent number: 6423296Abstract: The invention relates to MR contrast media containing composite nanoparticles, preferably comprising a superparamagnetic iron oxide core provided with a coating comprising an oxidatively cleaved starch coating optionally together with a functionalized polyalkyleneoxide which serves to prolong blood residence.Type: GrantFiled: February 22, 1999Date of Patent: July 23, 2002Assignee: Amersham Health ASInventors: Wolfgang Gunther, Kenneth Kellar, Dennis Kiyoshi Fujii, Vinay Desai, Christopher Black, Marshall Beeber, Jennifer Wellons, Anne Kjersti Fahlvik, Jasbir Singh, Edward Richard Bacon, Gregory Lynn McIntire, Robert Alan Snow, Brian Weekley, Torgrim Engell, Michel Gacek, David Lee Ladd, Anne Naevestad, George Na, Barbara Yuan, Jack Stevens