Patents by Inventor Christopher Broder

Christopher Broder has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20200123623
    Abstract: The present disclosure is directed towards a virus, called Cedar Virus, and its methods of use.
    Type: Application
    Filed: March 12, 2019
    Publication date: April 23, 2020
    Applicants: Commonwealth Scientific and Industrial Research Organization, The State of Queensland, Department of Agriculture, Fisheries and Forestry
    Inventors: Linfa Wang, Glenn A. Marsh, Hume Field, Christopher Broder
  • Patent number: 10590172
    Abstract: This invention relates to soluble forms of F glycoprotein from Hendra and Nipah virus and to compositions comprising soluble forms of F glycoprotein from Hendra and Nipah virus. This invention further relates to soluble oligomers of F glycoprotein from Hendra and Nipah virus. This invention also relates to nucleic acids encoding soluble forms of F glycoprotein from Hendra and Nipah virus. This invention also relates to diagnostic and therapeutic methods using the soluble forms of F glycoprotein from Hendra and Nipah virus. Further, this invention relates to antibodies, including neutralizing antibodies, and to vaccines for the prevention, diagnosis and treatment of infection by Hendra and Nipah viruses.
    Type: Grant
    Filed: August 6, 2018
    Date of Patent: March 17, 2020
    Assignee: The Henry M. Jackson Foundation for the Advancement of Military Medicine, Inc.
    Inventors: Yee-peng Chan, Christopher Broder
  • Patent number: 10227664
    Abstract: The present invention is directed towards a novel virus, called Cedar Virus, and its methods of use.
    Type: Grant
    Filed: June 13, 2016
    Date of Patent: March 12, 2019
    Assignees: The Henry M. Jackson Foundation for the Advancement of Military Medicine, Inc., The State of Queensland, Department of Agriculture, Fisheries and Forestry, Commonwealth Scientific and Industrial Research Organization
    Inventors: Linfa Wang, Glenn A. Marsh, Hume Field, Christopher Broder
  • Publication number: 20190031721
    Abstract: This invention relates to soluble forms of F glycoprotein from Hendra and Nipah virus and to compositions comprising soluble forms of F glycoprotein from Hendra and Nipah virus. This invention further relates to soluble oligomers of F glycoprotein from Hendra and Nipah virus. This invention also relates to nucleic acids encoding soluble forms of F glycoprotein from Hendra and Nipah virus. This invention also relates to diagnostic and therapeutic methods using the soluble forms of F glycoprotein from Hendra and Nipah virus. Further, this invention relates to antibodies, including neutralizing antibodies, and to vaccines for the prevention, diagnosis and treatment of infection by Hendra and Nipah viruses.
    Type: Application
    Filed: August 6, 2018
    Publication date: January 31, 2019
    Applicant: THE HENRY M. JACKSON FOUNDATION FOR THE ADVANCEMENT OF MILITARY MEDICINE, INC.
    Inventors: Yee-peng CHAN, Christopher BRODER
  • Patent number: 10040825
    Abstract: This invention relates to soluble forms of F glycoprotein from Hendra and Nipah virus and to compositions comprising soluble forms of F glycoprotein from Hendra and Nipah virus. This invention further relates to soluble oligomers of F glycoprotein from Hendra and Nipah virus. This invention also relates to nucleic acids encoding soluble forms of F glycoprotein from Hendra and Nipah virus. This invention also relates to diagnostic and therapeutic methods using the soluble forms of F glycoprotein from Hendra and Nipah virus. Further, this invention relates to antibodies, including neutralizing antibodies, and to vaccines for the prevention, diagnosis and treatment of infection by Hendra and Nipah viruses.
    Type: Grant
    Filed: December 19, 2008
    Date of Patent: August 7, 2018
    Assignee: The Henry M. Jackson Foundation for the Advancement of Military Medicine, Inc.
    Inventors: Yee-peng Chan, Christopher Broder
  • Patent number: 10021470
    Abstract: A microphone has a sensing element; a casing surrounds the microphone with an opening that admits sound to the sensing element in a first direction. A spark director includes a first portion spaced away from the casing in a direction opposite the first direction, and a second portion extending from the first portion towards the casing and terminating in a tip separated from the casing by an air gap. An electric charge in the first portion of the spark director will be discharged by the second portion of the spark director through the air gap into the casing at a location other than at the opening.
    Type: Grant
    Filed: October 3, 2016
    Date of Patent: July 10, 2018
    Assignee: Bose Corporation
    Inventors: Ryan C. Silvestri, Adam Christopher Broders, Rebecca Kowalczyk
  • Publication number: 20180098143
    Abstract: A microphone has a sensing element; a casing surrounds the microphone with an opening that admits sound to the sensing element in a first direction. A spark director includes a first portion spaced away from the casing in a direction opposite the first direction, and a second portion extending from the first portion towards the casing and terminating in a tip separated from the casing by an air gap. An electric charge in the first portion of the spark director will be discharged by the second portion of the spark director through the air gap into the casing at a location other than at the opening.
    Type: Application
    Filed: October 3, 2016
    Publication date: April 5, 2018
    Applicant: Bose Corporation
    Inventors: Ryan C. Silvestri, Adam Christopher Broders, Rebecca Kowalczyk
  • Publication number: 20160362755
    Abstract: The present invention is directed towards a novel virus, called Cedar Virus, and its methods of use.
    Type: Application
    Filed: June 13, 2016
    Publication date: December 15, 2016
    Applicants: Commonwealth Scientific and Industrial Research Organization, The State of Queensland, Department of Agriculture, Fisheries and Forestry
    Inventors: Linfa Wang, Glenn A. Marsh, Hume Field, Christopher Broder
  • Publication number: 20160347827
    Abstract: The present invention relates to antibodies or antibody fragments that bind, neutralize, and/or inhibit Hendra or Nipah virus. The invention provides antibodies or antibody fragments that selectively bind to the F glycoprotein of Hendra or Nipah virus, and pharmaceutical compositions including such antibodies and/or fragments. The invention further provides polynucleotides encoding the antibodies and fragments of the invention and host cells transformed therewith. Additionally, the invention discloses prophylactic, therapeutic, and diagnostic methods employing the antibodies, fragments, polynucleotides, and/or compositions of the invention.
    Type: Application
    Filed: January 23, 2015
    Publication date: December 1, 2016
    Inventors: Chan C. YEE-PENG, Christopher BRODER
  • Publication number: 20150191702
    Abstract: The present invention is directed towards a novel virus, called Cedar Virus, and its methods of use.
    Type: Application
    Filed: July 2, 2013
    Publication date: July 9, 2015
    Applicants: Commonwealth Scientific and Industrial Research Organization, The State of Queensland, Department of Agriculture Fisheries and Forestry
    Inventors: Linfa Wang, Glenn A. Marsh, Hume Field, Christopher Broder
  • Publication number: 20130346672
    Abstract: The subject disclosure is directed towards a multi-tiered cache having cache tiers with different access properties. Objects are written to a selected a tier of the cache based upon object-related properties and/or cache-related properties. In one aspect, objects are stored in an active log among a plurality of logs. The active log is sealed upon reaching a target size, with a new active log opened. Garbage collecting is performed on a sealed log, such as the sealed log with the most garbage therein.
    Type: Application
    Filed: June 22, 2012
    Publication date: December 26, 2013
    Applicant: MICROSOFT CORPORATION
    Inventors: Sudipta Sengupta, Jin Li, Cheng Huang, Timothy Andrew Pritchett, Christopher Broder Wilson
  • Patent number: 8597658
    Abstract: This invention relates to fusion polypeptides comprised of a trimerization domain fused to a non-membrane bound, non-cleaved gp160 polypeptide derived from the R2 HIV-1 Env glycoprotein and to compositions comprising the fusion polypeptides. This invention further relates to oligomers of the fusion polypeptides. This invention also relates to nucleic acids encoding the fusion polypeptides. This invention also relates to diagnostic and therapeutic methods using the fusion polypeptides. Further, this invention relates to the induction of cross-reactive neutralizing antibodies against HIV-1, and to immunogenic compositions for the prevention and treatment of infection by HIV-1.
    Type: Grant
    Filed: November 12, 2008
    Date of Patent: December 3, 2013
    Assignee: The Henry M. Jackson Foundation for the Advancement of Military Medicine, Inc.
    Inventors: Gerald Quinnan, Christopher Broder
  • Publication number: 20130263151
    Abstract: Described is a technology by which a consistent hashing table of bins maintains values representing nodes of a distributed system. An assignment stage uses a consistent hashing function and a selection algorithm to assign values that represent the nodes to the bins. In an independent mapping stage, a mapping mechanism deterministically maps an object identifier/key to one of the bins as a mapped-to bin.
    Type: Application
    Filed: April 3, 2012
    Publication date: October 3, 2013
    Applicant: MICROSOFT CORPORATION
    Inventors: Jin Li, Cheng Huang, Sudipta Sengupta, Christopher Broder Wilson
  • Publication number: 20120039923
    Abstract: The present invention relates to modified HIV-1 envelope proteins where one or more N-glycosylation sites have been deleted or modified, which produce a broadly cross reactive neutralizing response, their methods of use and antibodies which bind to these proteins. The invention also provides for nucleic acids, vectors, antibodies and pharmaceutical compositions that comprise said modified HIV-1 envelope proteins.
    Type: Application
    Filed: September 9, 2005
    Publication date: February 16, 2012
    Applicant: THE HENRY M. JACKSON FOUNDATION
    Inventors: Christopher Broder, Gerald Quinnan
  • Publication number: 20110223172
    Abstract: This invention relates to soluble forms of F glycoprotein from Hendra and Nipah virus and to compositions comprising soluble forms of F glycoprotein from Hendra and Nipah virus. This invention further relates to soluble oligomers of F glycoprotein from Hendra and Nipah virus. This invention also relates to nucleic acids encoding soluble forms of F glycoprotein from Hendra and Nipah virus. This invention also relates to diagnostic and therapeutic methods using the soluble forms of F glycoprotein from Hendra and Nipah virus. Further, this invention relates to antibodies, including neutralizing antibodies, and to vaccines for the prevention, diagnosis and treatment of infection by Hendra and Nipah viruses.
    Type: Application
    Filed: December 19, 2008
    Publication date: September 15, 2011
    Inventors: Yee-peng Chan, Christopher Broder
  • Publication number: 20100316661
    Abstract: This invention relates to fusion polypeptides comprised of a trimerization domain fused to a non-membrane bound, non-cleaved gp160 polypeptide derived from the R2 HIV-1 Env glycoprotein and to compositions comprising the fusion polypeptides. This invention further relates to oligomers of the fusion polypeptides. This invention also relates to nucleic acids encoding the fusion polypeptides. This invention also relates to diagnostic and therapeutic methods using the fusion polypeptides. Further, this invention relates to the induction of cross-reactive neutralizing antibodies against HIV-1, and to immunogenic compositions for the prevention and treatment of infection by HIV-1.
    Type: Application
    Filed: November 12, 2008
    Publication date: December 16, 2010
    Inventors: Gerald Quinnan, Christopher Broder
  • Publication number: 20100147832
    Abstract: An induction cooking system including one or more methods or apparatus for identifying items of cookware. The identifying may include identifying whether in use, the temperature of the outside surface of the element of cookware is significantly lower than the temperature of the inside surface. The methods may include one or more of measuring impedance, communicating information by RF radiation, or measuring reactance.
    Type: Application
    Filed: December 16, 2008
    Publication date: June 17, 2010
    Inventors: Charles R. Barker, III, Carolyn E. Modiano, Adam Christopher Broders, Raymond O. England, Anthony G. Esposito, Thomas A. Froeschle, Alfred G. Giombetti, John Michael Kitchura, JR., Michael Nussbaum, Laura J. Schroeder
  • Publication number: 20070087990
    Abstract: The susceptibility of human macrophages to human immunodeficiency virus (HIV) infection depends on cell surface expression of the human CD4 molecule and CC cytokine receptor 5. CCR5 is a member of the 7-transmembrane segment superfamily of G-protein-coupled cell surface molecules. CCR5 plays an essential role in the membrane fusion step of infection by some HIV isolates. The establishment of stable, nonhuman cell lines and transgenic mammals having cells that coexpress human CD4 and CCR5 provides valuable tools for the continuing research of HIV infection. In addition, antibodies which bind to CCR5, CCR5 variants, and CCR5-binding agents, capable of blocking membrane fusion between HIV and target cells represent potential anti-HIV therapeutics for macrophage-tropic strains of HIV.
    Type: Application
    Filed: November 7, 2006
    Publication date: April 19, 2007
    Inventors: Christophe Combadiere, Yu Feng, Ghalib Alkhatib, Edward Berger, Philip Murphy, Christopher Broder, Paul Kennedy
  • Publication number: 20060233821
    Abstract: Fusion of the membrane of enveloped viruses with the plasma membrane of a receptive host cell is a prerequisite for viral entry and infection and an essential step in the life cycle of all enveloped viruses, such as paramyxoviruses. The instant invention is directed to providing polypeptides which are a heptad portion of a Henipavirus F protein effective against fusion between a membrane of a paramyxovirus and a plasma membrane of a cell. The instant invention also provides nucleic acids, compositions, and methods effective against paramyxovirus infection. Accordingly, the instant invention provides therapeutic agents and vaccines effective against paramyxoviruses viruses, especially HeV or NiV.
    Type: Application
    Filed: November 13, 2002
    Publication date: October 19, 2006
    Inventors: Christopher Broder, Katharine Bossart
  • Publication number: 20050106160
    Abstract: This invention relates generally to immune responses to human immunodeficiency virus coat protein gp160 presented in the form of antigenic compositions, nucleic acids encoding human immunodeficiency virus coat proteins, and vaccines. The invention also relates to methods for production of antigenic compositions containing human immunodeficiency virus coat protein, nucleic acids encoding human immunodeficiency virus coat proteins, and human immunodeficiency virus vaccines. The invention comprises gp120 and gp41 subunits of the human immunodeficiency virus coat protein covalently linked through a peptide linker, as well as additional complexes including those comprising the human immunodeficiency virus coat protein and it's natural cellular receptor molecules.
    Type: Application
    Filed: March 5, 2002
    Publication date: May 19, 2005
    Inventors: Dimiter Dimitrov, Yen-Hung Chow, Sanjay Phogat, Christopher Broder