Abstract: Disclosed herein are pre-filled multi-fluid medical delivery assemblies and methods for fabrication and use thereof.

Abstract: Systems for processing articles are essential for semiconductor fabrication. These systems employ a variety of apparatuses for controlling flow. In one implementation, an apparatus for controlling flow may utilize a body having a flow path extending from an inlet to an outlet. A valve, a flow restrictor, and a pressure sensor are operably coupled to the flow path. The valve incorporates first and second actuators which enable control of mass flow rates of fluid flowing through the flow path.

Abstract: A workpiece-depowdering method and apparatus are provided. In another aspect, a method includes: robotically gripping an additively manufactured workpiece within an enclosure; and automatically blowing gas onto the additively manufactured workpiece to remove extra powder from the additively manufactured workpiece. A further method includes: additively layering powder within an additive manufacturing station, moving the additively manufactured workpiece to a depowdering station; holding the additively manufactured workpiece adjacent to the at least one nozzle with an automatically controlled gripper within the depowdering station; and depowdering the additively manufactured workpiece in the depowdering station by the gas. Another aspect provides a machine including: a robot configured to grip a workpiece; and a nozzle configured to blow excess powder off of the workpiece.

Abstract: Systems for manufacturing semiconductors are essential to enabling modern technologies. Such systems may include a central controller, a plurality of fluid supplies, a plurality of apparatus for controlling flow, and a processing chamber. The central controller may have a processor, a memory, and a communication module. The plurality of apparatus for controlling flow may have a device controller having an active component, a sensor, and a communication module. The communication may have a communication module, a memory, a sensor drive circuit operably coupled to the sensor, and an active component drive operably coupled to the active component. The central controller is configured to receive sensor data from the sensors of the plurality of apparatus for controlling flow and transmit active component commands to the active component drives of the device controllers to control the plurality of apparatus for controlling flow.

Abstract: The present invention relates to relates to a polymer formulation for three-dimensionally (3D) printing an article by stereolithography, the formulation comprising a functionalized polymer. The invention further relates to lithographic methods to form 3D objects that incorporate the aforementioned polymer formulation.

Abstract: Systems for processing articles are essential for semiconductor fabrication. In one embodiment, a system is disclosed comprising a plurality of fluid supplies configured to supply process fluids, a plurality of apparatuses for controlling flow, a plurality of mounting substrates, a vacuum manifold fluidly coupled to the plurality of mounting substrates, an outlet manifold fluidly coupled to the plurality of mounting substrates, a vacuum source fluidly coupled to the vacuum manifold, and a processing chamber fluidly coupled to the outlet manifold. The plurality of apparatuses for controlling flow have a bleed port and an outlet. The outlets of the plurality of apparatuses are fluidly coupled to corresponding outlet ports of the plurality of mounting substrates. The bleed ports of the plurality of apparatuses are fluidly coupled to the corresponding vacuum ports of the plurality of mounting substrates.

Abstract: The present disclosure includes a method of making an improved carbetocin drug product. The disclosed method for making an improved carbetocin drug product comprises agitating a carbetocin preparation containing an aqueous solution of carbetocin and one or more excipients for a period of to initiate the formation of aggregate-forming solids and filtering off the aggregates that form before further processing the remaining carbetocin into a final drug product. The present disclosure also relates to an improved carbetocin drug product, wherein the drug product is substantially free of aggregate-forming solids. The disclosed carbetocin drug product can be used for the treatment of a neurodevelopmental disorder, such as Präder-Willi syndrome. Additionally, the disclosed carbetocin drug product shows content uniformity of carbetocin over long periods of time before and after one or more free/thaw cycles, provides enhanced convenience and patient compliance, and/or are highly concentrated.

Abstract: Apparatuses for controlling gas flow are important components for delivering process gases for semiconductor fabrication. These apparatuses for controlling gas flow frequently rely on flow restrictors which can provide a known flow impedance of the process gas. In one embodiment, a flow restrictor is disclosed, the flow restrictor constructed of a plurality of layers, one or more of the layers having a flow passage therein that extends from a first aperture at a first end of the flow restrictor to a second aperture at a second end of the flow restrictor.

Abstract: A gas flow control system for delivering a plurality of gas flows. The gas flow control system has a gas flow path extending from a gas inlet to first and second gas outlets. First and second flow restrictors are operably coupled to the gas flow path. First and second valves are operably coupled to the gas flow path such that when both first and second valves are in a fully open state, flows of gas from the first and second gas outlets are split according to the impedances of the first and second flow restrictors.

Abstract: The present disclosure includes a method of making an improved carbetocin drug product. The disclosed method for making an improved carbetocin drug product comprises agitating a carbetocin preparation containing an aqueous solution of carbetocin and one or more excipients for a period of time to initiate the formation of aggregate-forming solids and filtering off the aggregates that form before further processing the remaining carbetocin into a final drug product. The present disclosure also relates to an improved carbetocin drug product, wherein the drug product is substantially free of aggregate-forming solids. The disclosed carbetocin drug product can be used for the treatment of a neurodevelopmental disorder, such as Präder-Willi syndrome. Additionally, the disclosed carbetocin drug product shows content uniformity of carbetocin over long periods of time before and after one or more freeze/thaw cycles, provides enhanced convenience and patient compliance, and/or are highly concentrated.

Abstract: Apparatuses for controlling gas flow are important components for delivering process gases for semiconductor fabrication. These apparatuses for controlling gas flow frequently rely on flow restrictors which can provide a known flow impedance of the process gas. In one embodiment, a flow restrictor is disclosed, the flow restrictor constructed of a plurality of layers, one or more of the layers having a flow passage therein that extends from a first aperture at a first end of the flow restrictor to a second aperture at a second end of the flow restrictor.

Abstract: A system includes a supply receptacle defining one or more supply receptacle sidewalls and an upwardly-facing receptacle opening, a piston positioned at least partially within the supply receptacle, where the piston, the upwardly-facing receptacle opening, and the one or more supply receptacle sidewalls at least partially define an interior space of the supply receptacle, and the piston is positionable between an extended position, in which the interior space has an extended volume, and a retracted position, in which the interior space has a retracted volume that is greater than the extended volume, and a dosing hopper positioned above and in selective communication with the interior space of the supply receptacle, where the dosing hopper is structurally configured to deliver build material to the interior space.

Abstract: A system (100) includes a build area positioned along a working surface (102), a supply receptacle (110) spaced apart from the build area and defining one or more supply receptacle sidewalls and an upwardly-facing receptacle opening (114), a dosing hopper (240) positioned above and in selective communication with the supply receptacle, where the dosing hopper is structurally configured to deliver build material to an interior space (116), and a conveyance hopper (260) in communication with the dosing hopper (240).

Abstract: A first feature is displayed within a first view of a user interface. A first selection of the first feature is configured to display a first set of identifiers corresponding to one or more tasks. A second feature is displayed within the first view of the user interface. A second selection of the second feature is configured to display a second set of identifiers corresponding to a set of workers. Each worker of the set of workers is associated with the one or more tasks and a first time that the one or more tasks are scheduled to be completed by. A set of status indicators are displayed. Each status indicator of the set of status indicators indicates whether the one or more tasks have been completed by the first time for the each worker of the set of workers based at least in part on the associating.

Abstract: The present invention relates to poly(amide imide) (PAI) precursor polymers which can for example be used in Vat photopolymerization processes like lithographic processes for the photofabrication of three-dimensional (3D) articles. The invention further relates to polymer compositions including these poly(amide imide) (PAI) precursor polymers. Still further, the invention relates to vat photopolymerization methods to form three-dimensional (3D) objects that incorporate the aforementioned polymer compositions.

Abstract: A first feature is displayed within a first view of a user interface. A first selection of the first feature is configured to display a first set of identifiers corresponding to one or more tasks. A second feature is displayed within the first view of the user interface. A second selection of the second feature is configured to display a second set of identifiers corresponding to a set of workers. Each worker of the set of workers is associated with the one or more tasks and a first time that the one or more tasks are scheduled to be completed by. A set of status indicators are displayed. Each status indicator of the set of status indicators indicates whether the one or more tasks have been completed by the first time for the each worker of the set of workers based at least in part on the associating.

Abstract: A water-soluble polyurethane derived from: polyethylene glycol, polyethylene glycol-block-polypropylene glycol-block-polyethylene glycol polymer, polypropylene glycol-block-polyethylene glycol-block-polypropylene and mixtures thereof, 1,1?-Carbonyldiimidazole, polyamine and mixtures thereof.

Abstract: The application describes stable aqueous compositions comprising relatively high concentrations of carbetocin and a solubilizer and/or surface active agent. The disclosed carbetocin compositions are effective in the treatment of a neurodevelopmental disorder, such as Prader-Willi syndrome. Additionally, the disclosed carbetocin compositions show improved stability at room temperature and/or under accelerated conditions of stress.

Abstract: Aspects of the subject disclosure may include, for example, receiving, by a processing system including a processor that is operative in a first communication network, a certificate from a communication device that is operative in a second communication network, extracting, by the processing system, an identifier of the communication device from the certificate, authenticating, by the processing system, the communication device in accordance with the identifier, comparing, by the processing system, the identifier with a plurality of identifiers to determine that the communication device is authorized to access data, resulting in an authorization determination, and transmitting, by the processing system, the data to the communication device based on the authorization determination. Other embodiments are disclosed.

Abstract: The present invention relates to relates to a polymer formulation for three-dimensionally (3D) printing an article by stereolithography, the formulation comprising a functionalized polymer. The invention further relates to lithographic methods to form 3D objects that incorporate the aforementioned polymer formulation.