Patents by Inventor Christopher Buchko

Christopher Buchko has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Methods for immobilizing anti-thrombogenic material onto a medical device or into a coating thereon
    Patent number: 8263170
    Abstract: The present invention is directed to a medical device having a polymerized base coat layer for the immobilization of an anti-thrombogenic material, such as heparin, thereon. The binding coat layer is comprised of various chemically functional groups which are stable and allow for the immobilization of the anti-thrombogenic material thereto. Methods for immobilizing the anti-thrombogenic material within the base coat layer posited on a surface of the medical device are also provided.
    Type: Grant
    Filed: January 6, 2010
    Date of Patent: September 11, 2012
    Assignee: Advanced Cardiovascular Systems, Inc.
    Inventors: Eugene T. Michal, Ni Ding, Christopher Buchko
  • Guided deposition in spatial arrays
    Publication number: 20050196745
    Abstract: An apparatus and method is provided for preparing and using a very large and diverse array of compounds on a substrate having rapidly accessible locations. The substrate contains cells in which the compounds of the array are located. Surrounding the cells is a non-wetable surface that prevents the solution in one cell from moving to adjacent cells. The compounds are delivered to the individual cells of the array by a micropipette attached to an X-Y translation stage.
    Type: Application
    Filed: December 16, 2004
    Publication date: September 8, 2005
    Applicant: Affymetrix, INC.
    Inventors: Alejandro Zaffaroni, Christopher Buchko, Douglas Modlin
  • Combinatorial strategies for polymer synthesis
    Publication number: 20050186683
    Abstract: A method and device for forming large arrays of polymers on a substrate (401). According to a preferred aspect of the invention, the substrate is contacted by a channel block (407) having channels (409) therein. Selected reagents are delivered through the channels, the substrate is rotated by a rotating stage (403), and the process is repeated to form arrays of polymers on the substrate. The method may be combined with light-directed methodolgies.
    Type: Application
    Filed: November 24, 2004
    Publication date: August 25, 2005
    Applicants: Affymetrix, Inc., AFFYMAX TECHNOLOGIES N.V.
    Inventors: James Winkler, Stephen Fodor, Christopher Buchko, Debra Ross, Lois Aldwin, Douglas Modlin
  • Combinatorial strategies for polymer synthesis
    Publication number: 20050186592
    Abstract: A method and device for forming large arrays of polymers on a substrate (401). According to a preferred aspect of the invention, the substrate is contacted by a channel block (407) having channels (409) therein. Selected reagents are delivered through the channels, the substrate is rotated by a rotating stage (403), and the process is repeated to form arrays of polymers on the substrate. The method may be combined with light-directed methodolgies.
    Type: Application
    Filed: November 24, 2004
    Publication date: August 25, 2005
    Applicants: Affymetrix, Inc., AFFYMAX TECHNOLOGIES N.V.
    Inventors: James Winkler, Stephen Fodor, Christopher Buchko, Debra Ross, Lois Aldwin, Douglas Modlin
  • Guided deposition in spatial arrays
    Publication number: 20050176058
    Abstract: An apparatus and method is provided for preparing and using a very large and diverse array of compounds on a substrate having rapidly accessible locations. The substrate contains cells in which the compounds of the array are located. Surrounding the cells is a non-wetable surface that prevents the solution in one cell from moving to adjacent cells. The compounds are delivered to the individual cells of the array by a micropipette attached to an X-Y translation stage.
    Type: Application
    Filed: April 6, 2005
    Publication date: August 11, 2005
    Applicant: Affymetrix, Inc.
    Inventors: Alejandro Zaffaroni, Christopher Buchko, Douglas Modlin
  • Combinatorial strategies for polymer synthesis
    Publication number: 20050124000
    Abstract: A method and device for forming large arrays of polymers on a substrate (401). According to a preferred aspect of the invention, the substrate is contacted by a channel block (407) having channels (409) therein. Selected reagents are delivered through the channels, the substrate is rotated by a rotating stage (403), and the process is repeated to form arrays of polymers on the substrate. The method may be combined with light-directed methodolgies.
    Type: Application
    Filed: November 24, 2004
    Publication date: June 9, 2005
    Applicants: Affymetrix, Inc., AFFYMAX TECHNOLOGIES N.V., a Netherlands Antilles corporation
    Inventors: James Winkler, Stephen Fodor, Christopher Buchko, Debra Ross, Lois Aldwin, Douglas Modlin