Abstract: An industrial power system includes a hybrid electric transmission assembly to transfer power from an internal combustion engine to an industrial load. The transmission assembly includes a first driveshaft coupled to the engine and a second driveshaft coupled to the load with a primary drivetrain gear assembly coupling the first driveshaft to the second driveshaft. An electric drive gearset is disposed between the primary drivetrain gear assembly and the load. An electric motor is couplable to the electric drive gearset, thereby allowing power to be passed from the electric motor to drive the load and bypass the primary drivetrain gear assembly during the gear change. The system may include a plurality of electric motors each having an electric motor axis and an output gearset coupled to the electric drive gearset, where each of the electric motor axii are spaced radially outward from the first and second driveshafts.

Abstract: A hydraulic fracturing system includes a hybrid electric transmission assembly to transfer power from an internal combustion engine to a hydraulic fracturing pump. The transmission assembly includes a first driveshaft coupled to the engine and a second driveshaft coupled to the pump with a primary drivetrain gear assembly coupling the first driveshaft to the second driveshaft. An electric drive gearset is disposed between the primary drivetrain gear assembly and the pump. An electric motor is couplable to the electric drive gearset, thereby allowing power to be passed from the electric motor to drive the pump and bypass the primary drivetrain gear assembly during the gear change. The system may include a plurality of electric motors each having an electric motor axis and an output gearset coupled to the electric drive gearset, where each of the electric motor axii are spaced radially outward from the first and second driveshafts.

Abstract: A power generation system has an engine disposed to drive a generator assembly having a plurality of electric generators supported on a gearbox housing. The gearbox housing encloses a gear assembly with an input driveshaft extending along a primary gear assembly axis. A drive gearset mounted on the input driveshaft is coupled to a plurality of output gearsets, each of which mounted on a separate gear assembly output driveshaft. Each gear assembly output driveshaft is parallel with but spaced radially outward from the primary gear assembly axis. At least one electric generator is mechanically coupled to each of the gear assembly output driveshafts.

Abstract: An industrial power system includes a hybrid electric transmission assembly to transfer power from an internal combustion engine to an industrial load. The transmission assembly includes a first driveshaft coupled to the engine and a second driveshaft coupled to the load with a primary drivetrain gear assembly coupling the first driveshaft to the second driveshaft. An electric drive gearset is disposed along a primary axis spaced apart from the primary drivetrain gear assembly. An electric motor is couplable to the electric drive gearset, thereby allowing the electric motor to provide equilibrium power to the system during a gear change of the primary drivetrain gear assembly. The electric motors are energized at the beginning of a gear change by discharging a supercapacitor electrically coupled to the electric motors to minimize torque pulldown from the external load, after which a more stable supply of electricity is provided to the electric motors.

Abstract: An industrial power system includes a hybrid electric transmission assembly to transfer power from an internal combustion engine to an industrial load. The transmission assembly includes a first driveshaft coupled to the engine and a second driveshaft coupled to the load with a primary drivetrain gear assembly coupling the first driveshaft to the second driveshaft. An electric drive gearset is disposed between the primary drivetrain gear assembly and the load. An electric motor is couplable to the electric drive gearset, thereby allowing power to be passed from the electric motor to drive the load and bypass the primary drivetrain gear assembly during the gear change. The system may include a plurality of electric motors each having an electric motor axis and an output gearset coupled to the electric drive gearset, where each of the electric motor axii are spaced radially outward from the first and second driveshafts.

Abstract: A medical system useful in the determination of future disease progression in a subject. More specifically the present invention applies machine learning techniques to aid prediction of disease pathology and clinical outcomes in subjects presenting with symptoms of cognitive decline and to expedite clinical development of novel therapeutics.

Abstract: A hydraulic fracturing system includes a hybrid electric transmission assembly to transfer power from an internal combustion engine to a hydraulic fracturing pump. The transmission assembly includes a first driveshaft coupled to the engine and a second driveshaft coupled to the pump with a primary drivetrain gear assembly coupling the first driveshaft to the second driveshaft. An electric drive gearset is disposed between the primary drivetrain gear assembly and the pump. An electric motor is couplable to the electric drive gearset, thereby allowing power to be passed from the electric motor to drive the pump and bypass the primary drivetrain gear assembly during the gear change. The system may include a plurality of electric motors each having an electric motor axis and an output gearset coupled to the electric drive gearset, where each of the electric motor axii are spaced radially outward from the first and second driveshafts.

Abstract: An industrial power system includes a hybrid electric transmission assembly to transfer power from an internal combustion engine to an industrial load. The transmission assembly includes a first driveshaft coupled to the engine and a second driveshaft coupled to the load with a primary drivetrain gear assembly coupling the first driveshaft to the second driveshaft. An electric drive gearset is disposed between the primary drivetrain gear assembly and the load. An electric motor is couplable to the electric drive gearset, thereby allowing power to be passed from the electric motor to drive the load and bypass the primary drivetrain gear assembly during the gear change. The system may include a plurality of electric motors each having an electric motor axis and an output gearset coupled to the electric drive gearset, where each of the electric motor axii are spaced radially outward from the first and second driveshafts.

Abstract: A system and method for rapid student verification using an online verification service for IRCC and CBSA officers to verify acceptance details quickly and easily for study permit applicants to one of the colleges using IAS. The solution can be easily accessed by IRCC and CBSA officers at using a website, where they will find a simple and straightforward lookup page and results, available in English and French.

Abstract: A valve seat includes a generally cylindrical body that defines a bore extending axially therethrough and has an outer surface. An enlarged diameter portion extends axially from the generally cylindrical body and defines a shoulder surface and an annular surface disposed opposite the shoulder surface; the annular surface is configured to form a seal with a displaceable portion of a valve. An annular channel is formed in the outer surface of the generally cylindrical body. An annular notch is formed in the outer surface of the generally cylindrical body axially between the enlarged diameter portion and the annular channel. The annular notch is configured to increase the radial compressibility of the generally cylindrical body to facilitate hydraulic ejection of the valve seat from the cylinder block. The annular channel is configured to receive a hydraulic fluid to compress radially the generally cylindrical body.

Abstract: A medical system useful in the determination of future disease progression in a subject. More specifically the present invention applies machine learning techniques to aid prediction of disease pathology and clinical outcomes in subjects presenting with symptoms of cognitive decline and to expedite clinical development of novel therapeutics.

Abstract: A valve seat includes a generally cylindrical body that defines a bore extending axially therethrough and has an outer surface. An enlarged diameter portion extends axially from the generally cylindrical body and defines a shoulder surface and an annular surface disposed opposite the shoulder surface; the annular surface is configured to form a seal with a displaceable portion of a valve. An annular notch is formed in the outer surface of the generally cylindrical body. The annular notch is configured to reduce a contact area between the outer surface and an interface surface of a cylinder block to facilitate hydraulic ejection of the valve seat from the cylinder block. An annular channel is formed in the outer surface of the generally cylindrical body and is disposed axially below the annular notch. The annular channel is configured to receive a hydraulic fluid to compress radially the generally cylindrical body.

Abstract: A valve seat includes a generally cylindrical body that defines a bore extending axially therethrough and has an outer surface. An enlarged diameter portion extends axially from the generally cylindrical body and defines a shoulder surface and an annular surface disposed opposite the shoulder surface; the annular surface is configured to form a seal with a displaceable portion of a valve. An annular notch is formed in the outer surface of the generally cylindrical body, and it extends a distance from a shoulder surface. The annular notch decouples a stiffness of the enlarged diameter portion to thereby increase a radial compressibility of the generally cylindrical body. An annular channel is formed in the outer surface of the generally cylindrical body and is disposed axially below the annular notch. The annular channel is configured to receive a hydraulic fluid to compress radially the generally cylindrical body.

Abstract: A valve seat includes a generally cylindrical body that defines a bore extending axially therethrough and has an outer surface. An enlarged diameter portion extends axially from the generally cylindrical body and defines a shoulder surface and an annular surface disposed opposite the shoulder surface; the annular surface is configured to form a seal with a displaceable portion of a valve. An annular notch is formed in the outer surface of the generally cylindrical body, and it extends a distance from a shoulder surface. The annular notch decouples a stiffness of the enlarged diameter portion to thereby increase a radial compressibility of the generally cylindrical body. An annular channel is formed in the outer surface of the generally cylindrical body and is disposed axially below the annular notch. The annular channel is configured to receive a hydraulic fluid to compress radially the generally cylindrical body.

Abstract: An apparatus and method according to which a fluid, such as a fracturing fluid, is pressurized. The apparatus includes a motor that produces a first rotational output including a first angular velocity, a pump operably coupled to the motor, the pump comprising a fluid end and a power end operably coupled to the fluid end, and a transmission operably coupled between the motor and the pump. The transmission receives the first rotational output as a first rotational input, the first rotational input including the first angular velocity, and converts the first rotational input into a second rotational output, the second rotational output including a second angular velocity. The power end receives the second rotational output as a second rotational input, the second rotational input including the second angular velocity. In some embodiments, the transmission is directly connected to, or part of, the pump and the motor.

Abstract: The present invention relates to methods and uses of FcRL4 expression and optionally RANKL expressing B cells as biomarkers and therapeutic target for treatment of an autoimmune and/or chronic diseases associated with joint inflammation, in particular Rheumatoid Arthritis (RA).

Abstract: The invention relates to liquid pharmaceutical compositions adapted to nasal administration. The liquid nasal formulations of the invention are characterized inter alia by having excellent and prolonged moisturizing properties.

Abstract: The invention relates to liquid pharmaceutical compositions adapted to nasal administration. The liquid nasal formulations of the invention are characterized inter alia by having excellent and prolonged moisturizing properties.