Abstract: The present invention is directed to the tartrate salt of a FAK inhibitor defined by formula (I) below, and the use of that inhibitor for treating a proliferative disease.

Abstract: The present invention is directed to the tartrate salt of a FAK inhibitor defined by formula I below, and the use of that inhibitor for treating a proliferative disease:

Abstract: Embodiments of the present disclosure may include a method for providing cross-platform multi-user compatibility in a cross-play cloud computing environment, the method including simulating at least one instance of an entertainment program. Embodiments may also include providing access to the at least one instance of the entertainment program asynchronously from two or more client devices via one of a plurality of independent entertainment platforms. In some embodiments, the two or more client devices may be able to engage in multi-user functionality within the at least one instance of the entertainment program via the one of a plurality of independent entertainment platforms. Embodiments may also include synchronizing the multi-user functionality within the at least one instance of the entertainment program.

Abstract: Disclosed are various examples for enrolling a device in a management service. An enrollment wizard can include a series of user interfaces to facilitate enrollment of a device in the management service. Enrollment data can be obtained from the user and sent to the management service for authentication of the user and device. A user interface object can be instantiated to access a webpage within a user interface of the enrollment wizard for downloading a configuration profile provided by the management service. A user can be redirected to a settings application to install the configuration profile.

Abstract: The present invention is directed to the tartrate salt of a FAK inhibitor defined by formula (I) below, and the use of that inhibitor for treating a proliferative disease.

Abstract: Methods, and system, and entertainment device are provided for identifying a user. A method includes detecting acceleration of a user manipulated component, comparing the detected acceleration with user acceleration that is associated with a user of the electronic device, identifying the user of the electronic device based on the comparison of the detected acceleration and the user acceleration, and operating the electronic device based on the identified user of the electronic device.

Abstract: A coffee capsule dispensing assembly that includes at least one substantially gelatin casing capsule or composite which contains a coffee concentrate or composite or coffee enhancing substance. The gelatin casing capsule with a hydrolyzed collagen gelatin portion is designed to dissolve in an aqueous solution. A housing assembly with a distal end and a proximal end is designed to contain the at least one gelatin casing capsule. A depressible button assembly is disposed substantially at the proximal end of the housing assembly and is designed to advance the at least one gelatin casing capsule toward the distal end of the housing assembly. A latch and release assembly at the distal end of the housing assembly is designed to singularly release the at least one gelatin casing capsule when the at least one gelatin casing capsule is advanced by the depressible button assembly.

Abstract: A transdermal delivery system (1) configured to deliver an active agent to human or animal tissue, comprising a penetrative electrode (2) of one polarity that provides an electrical contact (3) beneath the stratum corneum (20); a surface electrode (4) of the opposite polarisation to that of the penetrative electrode (2) that provides an electrical contact to the external surface of the skin (21) on the opposite side of the stratum corneum (20) to the electrical contact (3) of the penetrative electrode (2); a dispenser (5) configured to deliver of an active agent to the external surface of the skin (21) adjacent to an electrical contact of the surface electrode (4); a method of delivering the active agent to the tissue of a human or animal body using the transdermal delivery system (1) and an electrode assembly (10) for use in preparing the transdermal delivery system (1).

Abstract: Disclosed are various examples for enrolling a device in a management service. An enrollment wizard can include a series of user interfaces to facilitate enrollment of a device in the management service. Enrollment data can be obtained from the user and sent to the management service for authentication of the user and device. A user interface object can be instantiated to access a webpage within a user interface of the enrollment wizard for downloading a configuration profile provided by the management service. A user can be redirected to a settings application to install the configuration profile.

Abstract: A transdermal delivery system (1) configured to deliver an active agent to human or animal tissue, comprising a penetrative electrode (2) of one polarity that provides an electrical contact (3) beneath the stratum corneum (20); a surface electrode (4) of the opposite polarisation to that of the penetrative electrode (2) that provides an electrical contact to the external surface of the skin (21) on the opposite side of the stratum corneum (20) to the electrical contact (3) of the penetrative electrode (2); a dispenser (5) configured to deliver of an active agent to the external surface of the skin (21) adjacent to an electrical contact of the surface electrode (4); a method of delivering the active agent to the tissue of a human or animal body using the transdermal delivery system (1) and an electrode assembly (10) for use in preparing the transdermal delivery system (1).

Abstract: A system and method is provided for identifying shadow regions on a multi-element capacitive input device such as a smart phone, and in particular using analysis of shadow regions, where the user may not be in direct contact with the device, to identify more accurately the area on the device the user is selecting, the hand, left or right, used to do the selecting and to identify the user using the device.

Abstract: A fragrance sachet includes a holder for a medium such as vermiculite. The medium can be treated with fragrance materials such as essential oils. The holder comprises a pouch formed with different materials on opposing sides which form designated respective front and back of the sachet. The designated front material is selected to support the application of indicia and/or decorations, while the designated back material may have filter type characteristics, to facilitate fragrance dispersion. The use of heat-sealable opposing side materials particularly facilitates formation of the pouch using a form-fill-seal system. The resulting sachet product may be configured with self-standing and/or hanging support features which avoid damaging any associated finished surfaces.

Abstract: A fragrance sachet includes a holder for a medium such as vermiculite. The medium can be treated with fragrance materials such as essential oils. The holder comprises a pouch formed with different materials on opposing sides which form designated respective front and back of the sachet. The designated front material is selected to support the application of indicia and/or decorations, while the designated back material may have filter type characteristics, to facilitate fragrance dispersion. The use of heat-sealable opposing side materials particularly facilitates formation of the pouch using a form-fill-seal system. The resulting sachet product may be configured with self-standing and/or hanging support features which avoid damaging any associated finished surfaces.

Abstract: A fragrance sachet includes a holder for a medium such as vermiculite. The medium can be treated with fragrance materials such as essential oils. The holder comprises a pouch formed with different materials on opposing sides which form designated respective front and back of the sachet. The designated front material is selected to support the application of indicia and/or decorations, while the designated back material may have filter type characteristics, to facilitate fragrance dispersion. The use of heat-sealable opposing side materials particularly facilitates formation of the pouch using a form-fill-seal system. The resulting sachet product may be configured with self-standing and/or hanging support features which avoid damaging any associated finished surfaces.

Abstract: A fragrance sachet includes a holder for a medium such as vermiculite. The medium can be treated with fragrance materials such as essential oils. The holder comprises a pouch formed with different materials on opposing sides which form designated respective front and back of the sachet. The designated front material is selected to support the application of indicia and/or decorations, while the designated back material may have filter type characteristics, to facilitate fragrance dispersion. The use of heat-sealable opposing side materials particularly facilitates formation of the pouch using a form-fill-seal system. The resulting sachet product may be configured with self-standing and/or hanging support features which avoid damaging any associated finished surfaces.

Abstract: A fragrance sachet includes a holder for a medium such as vermiculite. The medium can be treated with fragrance materials such as essential oils. The holder comprises a pouch formed with different materials on opposing sides which form designated respective front and back of the sachet. The designated front material is selected to support the application of indicia and/or decorations, while the designated back material may have filter type characteristics, to facilitate fragrance dispersion. The use of heat-sealable opposing side materials particularly facilitates formation of the pouch using a form-fill-seal system. The resulting sachet product may be configured with self-standing and/or hanging support features which avoid damaging any associated finished surfaces.

Abstract: A fragrance sachet includes a holder for a medium such as vermiculite. The medium can be treated with fragrance materials such as essential oils. The holder comprises a pouch formed with different materials on opposing sides which form designated respective front and back of the sachet. The designated front material is selected to support the application of indicia and/or decorations, while the designated back material may have filter type characteristics, to facilitate fragrance dispersion. The use of heat-sealable opposing side materials particularly facilitates formation of the pouch using a form-fill-seal system. The resulting sachet product may be configured with self-standing and/or hanging support features which avoid damaging any associated finished surfaces.

Abstract: Disclosed are various examples generating and optimizing deployment configurations for devices enrolled with a management service. A computing environment can be employed to receive information pertaining to a desired configuration of enrolled devices during an ingestion process where at least one user interface is generated, where the information received includes a specification of a client application, a resource, and a policy for implementation on a plurality of client devices enrolled with a management service. The enrolled devices can have different operating system installed thereon. The computing environment can generate a deployment configuration using the information received during the ingestion process, where the deployment configuration is universal across the client devices independent of the different operating systems.

Abstract: Various arrangements for providing audio calibration are presented. A remote control may determine that it is in position for an audio-based command to be received by the remote control from a user. Via a condenser microphone incorporated as part of the remote control, a calibration sound may be output. The condenser microphone may receive the output the calibration sound in the form of a reflected sound that is an acoustic reflection of the calibration sound. The remote control may analyze an amount of time that has elapsed between outputting the calibration sound and receiving the reflected sound to determine a distance between the condenser microphone and the user. One or more audio input settings may be configured that are used for modifying audio received by the condenser microphone based on the determined distance.

Abstract: Various arrangements involving an absolute direction of a remote control device are presented herein. In response to user input received by a remote control device, the orientation of the remote control device may be determined. A compass heading direction in which the remote control device is pointed may be determined. An absolute direction may be determined based on the determined orientation and the determined compass heading. A target control device may be selected from a plurality of target control devices based on the absolute heading of the remote control device. A message indicative of the user input may then be transmitted to the selected target control device.