Abstract: An electronic gaming system includes a first electronic gaming machine configured to execute a wagering game, a first overhead display, and a progressive system server communicatively coupled to the first electronic gaming machine and the first overhead display. The progressive system server is configured to receive, from the first electronic gaming machine, a message including a first progressive jackpot level, transmit a message including a first progressive jackpot value associated with the first progressive jackpot level, receive a message including the first progressive jackpot level, a first progressive jackpot multiplier awarded in the wagering game, and a first multiplied progressive jackpot value, select, in response and from a database of jackpot celebration scenes, a first jackpot celebration scene, and display, on the first overhead display, the selected first jackpot celebration scene and the first multiplied progressive jackpot value.

Abstract: The present invention relates to a solid unit oral dosage form comprising sacubitril and valsartan in a 1:1 molar ratio, preferably in the form of the so-called angiotensin receptor neprilysin inhibitor (ARNI) LCZ696, which is a complex salt hydrate of sacubitril, valsartan, and sodium ions, appropriate for use in pediatrics or other patients where low and individual dosing is required or who encounter problems with swallowing e.g. as a result of a disease or because of age, to the manufacture of said solid dosage form and to invention embodiments relating to therapy using said dosage form.

Abstract: The present invention relates to canakinumab for use in reducing the risk of or preventing recurrent cardiovascular (CV) events in a patient with elevated hsCRP that has suffered myocardial infarction (MI).

Abstract: An electronic gaming system includes a first electronic gaming machine configured to execute a wagering game, a first overhead display, and a progressive system server communicatively coupled to the first electronic gaming machine and the first overhead display. The progressive system server is configured to receive, from the first electronic gaming machine, a message including a first progressive jackpot level, transmit a message including a first progressive jackpot value associated with the first progressive jackpot level, receive a message including the first progressive jackpot level, a first progressive jackpot multiplier awarded in the wagering game, and a first multiplied progressive jackpot value, select, in response and from a database of jackpot celebration scenes, a first jackpot celebration scene, and display, on the first overhead display, the selected first jackpot celebration scene and the first multiplied progressive jackpot value.

Abstract: The present invention relates to a solid unit oral dosage form comprising sacubitril and valsartan in a 1:1 molar ratio, preferably in the form of the so-called angiotensin receptor neprilysin inhibitor (ARNI) LCZ696, which is a complex salt hydrate of sacubitril, valsartan, and sodium ions, appropriate for use in pediatrics or other patients where low and individual dosing is required or who encounter problems with swallowing e.g. as a result of a disease or because of age, to the manufacture of said solid dosage form and to invention embodiments relating to therapy using said dosage form.

Abstract: The present invention relates to methods and pharmaceutical compositions for treating heart failure in a pediatric human patient comprising administration to said patient of a therapeutically effective amount or a prophylactically effective amount of a combination of a therapeutic agent blocking the angiotensin receptor and a therapeutic agent inhibiting the NEP enzyme, in particular of a combination of sacubitril and valsartan in a pharmaceutically acceptable form and in a 1:1 molar ratio.

Abstract: A buoyancy compensating element for connection to a flexible pipe and method of producing a buoyancy compensating element are disclosed. The buoyancy compensating element includes a first body portion and a further body portion, wherein the first and further body portion are configured to be connectable to each other and in use to encompass a portion of flexible pipe.

Abstract: A buoyancy compensating element for connection to a flexible pipe and method of producing a buoyancy compensating element are disclosed. The buoyancy compensating element includes a first body portion and a further body portion, wherein the first and further body portion are configured to be connectable to each other and in use to encompass a portion of flexible pipe.

Abstract: An ultrasonic probe includes a shaft having a longitudinal axis and a head disposed at a distal end of the shaft. The head has a cylindrical lateral surface and an end face oriented perpendicularly to the axis. The head has three shaping surfaces at a distal end of the cylindrical surface, each shaping surface extending at an acute angle to the axis. Each of the shaping surfaces intersects or is contiguous with both the cylindrical surface and the end face.

Abstract: An application includes a variety of metadata and operations that may process the metadata. Selective portions of the metadata are identified and various combinations of available operations are automatically generated for the selective metadata. Each generated operation is then individually validated for syntax and semantics, without actually executing the operation.

Abstract: An ultrasonic probe includes a shaft having a longitudinal axis and a head disposed at a distal end of the shaft. The head has a cylindrical lateral surface and an end face oriented perpendicularly to the axis. The head has three shaping surfaces at a distal end of the cylindrical surface, each shaping surface extending at an acute angle to the axis. Each of the shaping surfaces intersects or is contiguous with both the cylindrical surface and the end face.

Abstract: In preparation for a medical procedure utilizing a medical instrument such as a high intensity focused ultrasound probe sterile water is gravity fed to a reservoir container through a hydrophobic hollow fiber or membrane filter connected to a vacuum pump, whereby the reservoir container is filled with degassed sterile water. The reservoir is operatively connected to the medical instrument in a hydraulic circuit through which the degassed sterile water is pumped from the reservoir container. The circuit is purged of air and then closed to render the medical instrument in condition for a medical procedure.

Abstract: A liquid containment system in accordance with the present invention includes a flexible plastic or elastomeric bag with several apertures. Surrounding each aperture is a port member such as a silastic ring. The port member functions at least reduce the escape of airborne particules from the bag while permitting the insertion of a surgical instrument into the bag. The port member may be made at least partially of a silicone based material to provide resistance to damage by ultrasonic tools.