Patents by Inventor Christopher C. Fraser
Christopher C. Fraser has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 11363070Abstract: A computer security method including detecting a request, made by a computer software application, prior to transmission of the request to a recipient, accessing a predefined security requirement associated with the recipient, determining whether the predefined security requirement is met, and preventing at least a portion of the request from being transmitted to the recipient if the predefined security requirement is not met.Type: GrantFiled: January 5, 2020Date of Patent: June 14, 2022Assignee: INTERNATIONAL BUSINESS MACHINES CORPORATIONInventors: Olanrewaju O. Okunlola, Christopher C. Fraser
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Publication number: 20210211469Abstract: A computer security method including detecting a request, made by a computer software application, prior to transmission of the request to a recipient, accessing a predefined security requirement associated with the recipient, determining whether the predefined security requirement is met, and preventing at least a portion of the request from being transmitted to the recipient if the predefined security requirement is not met.Type: ApplicationFiled: January 5, 2020Publication date: July 8, 2021Inventors: OLANREWAJU O. OKUNLOLA, CHRISTOPHER C. FRASER
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Patent number: 11032304Abstract: A mechanism is provided in a data processing system comprising at least one processor and at least one memory, the at least one memory comprising instructions executed by the at least one processor to cause the at least one processor to implement an ontology based persistent attack campaign detection engine. In response to a security incident, the mechanism sends the security incident to an incident model microservice executing within the persistent attack campaign detection engine. The incident model microservice extracts artifacts from the incident, maps the artifacts to a graph topology data structure, and stores the graph topology data structure in a graph data storage.Type: GrantFiled: December 4, 2018Date of Patent: June 8, 2021Assignee: International Business Machines CorporationInventors: Olanrewaju O. Okunlola, Christopher C. Fraser, Matthew P. Ouellette
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Patent number: 10831868Abstract: A method, system, apparatus, and a computer program product are provided for managing a rate-based license by monitoring geographic location information for each of a plurality of users in different time zones and adjusting allocations of an application license for a user organization across the plurality of users based on the geographic location information for the plurality of users and an amount of the application license expected to be used during specified peak hours at each geographic location so that the application license is allocated to permit each usage for each user during the specified peak hours at each geographic location.Type: GrantFiled: April 2, 2018Date of Patent: November 10, 2020Assignee: International Business Machines CorporationInventor: Christopher C. Fraser
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Publication number: 20200177608Abstract: A mechanism is provided in a data processing system comprising at least one processor and at least one memory, the at least one memory comprising instructions executed by the at least one processor to cause the at least one processor to implement an ontology based persistent attack campaign detection engine. In response to a security incident, the mechanism sends the security incident to an incident model microservice executing within the persistent attack campaign detection engine. The incident model microservice extracts artifacts from the incident, maps the artifacts to a graph topology data structure, and stores the graph topology data structure in a graph data storage.Type: ApplicationFiled: December 4, 2018Publication date: June 4, 2020Inventors: Olanrewaju O. Okunlola, Christopher C. Fraser, Matthew P. Ouellette
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Publication number: 20190303542Abstract: A method, system, apparatus, and a computer program product are provided for managing a rate-based license by monitoring geographic location information for each of a plurality of users in different time zones and adjusting allocations of an application license for a user organization across the plurality of users based on the geographic location information for the plurality of users and an amount of the application license expected to be used during specified peak hours at each geographic location so that the application license is allocated to permit each usage for each user during the specified peak hours at each geographic location.Type: ApplicationFiled: April 2, 2018Publication date: October 3, 2019Inventor: Christopher C. Fraser
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Publication number: 20140296101Abstract: The invention provides isolated nucleic acid molecules, designated TANGO 228 nucleic acid molecules, which encode secreted proteins with homology to the rat MCA-32 protein, isolated nucleic acid molecules, designated TANGO 240 nucleic acid molecules, which encode secreted proteins with homology to the Mycobacterium tuberculosis hypothetical protein Rv0712, and isolated nucleic acid molecules, designated TANGO 243 nucleic acid molecules, which encode proteins with homology to human PLAP (phospholipase A2-activating protein). The invention also provides antisense nucleic acid molecules, expression vectors containing the nucleic acid molecules of the invention, host cells into which the expression vectors have been introduced, and non-human transgenic animals in which a nucleic acid molecule of the invention has been introduced or disrupted. The invention still further provides isolated polypeptides, fusion polypeptides, antigenic peptides and antibodies.Type: ApplicationFiled: May 2, 2014Publication date: October 2, 2014Applicant: Millennium Pharmaceuticals, Inc.Inventor: Christopher C. Fraser
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Publication number: 20130123122Abstract: The invention provides isolated nucleic acid molecules, designated TANGO 228 nucleic acid molecules, which encode secreted proteins with homology to the rat MCA-32 protein, isolated nucleic acid molecules, designated TANGO 240 nucleic acid molecules, which encode secreted proteins with homology to the Mycobacterium tuberculosis hypothetical protein Rv0712, and isolated nucleic acid molecules, designated TANGO 243 nucleic acid molecules, which encode proteins with homology to human PLAP (phospholipase A2-activating protein). The invention also provides antisense nucleic acid molecules, expression vectors containing the nucleic acid molecules of the invention, host cells into which the expression vectors have been introduced, and non-human transgenic animals in which a nucleic acid molecule of the invention has been introduced or disrupted. The invention still further provides isolated polypeptides, fusion polypeptides, antigenic peptides and antibodies.Type: ApplicationFiled: May 2, 2012Publication date: May 16, 2013Applicant: Millennium Pharmaceuticals, Inc.Inventor: Christopher C. Fraser
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NOVEL GENES ENCODING PROTEINS HAVING PROGNOSTIC, DIAGNOSTIC, PREVENTIVE, THERAPEUTIC, AND OTHER USES
Publication number: 20120270219Abstract: The invention provides isolated TANGO 509 nucleic acid molecules and polypeptide molecules. The invention also provides antisense nucleic acid molecules, expression vectors containing the nucleic acid molecules of the invention, host cells into which the expression vectors have been introduced, and non-human transgenic animals in which a nucleic acid molecule of the invention has been introduced or disrupted. The invention still further provides isolated polypeptides, fusion polypeptides, antigenic peptides and antibodies. Diagnostic, screening and therapeutic methods utilizing compositions of the invention are also provided.Type: ApplicationFiled: July 2, 2012Publication date: October 25, 2012Applicant: Millennium Pharmaceuticals, Inc.Inventors: Douglas A. Holtzman, John D. Sharp, Kevin R. Leiby, Steven Bossone, Yang Pan, Thomas M. Barnes, Christopher C. Fraser, Nicholas Wrighton, Paul S. Myers, Gillian Kingsbury -
Patent number: 8187819Abstract: The invention provides isolated nucleic acid molecules, designated TANGO 228 nucleic acid molecules, which encode secreted proteins with homology to the rat MCA-32 protein, isolated nucleic acid molecules, designated TANGO 240 nucleic acid molecules, which encode secreted proteins with homology to the Mycobacterium tuberculosis hypothetical protein Rv0712, and isolated nucleic acid molecules, designated TANGO 243 nucleic acid molecules, which encode proteins with homology to human PLAP (phospholipase A2-activating protein). The invention also provides antisense nucleic acid molecules, expression vectors containing the nucleic acid molecules of the invention, host cells into which the expression vectors have been introduced, and non-human transgenic animals in which a nucleic acid molecule of the invention has been introduced or disrupted. The invention still further provides isolated polypeptides, fusion polypeptides, antigenic peptides and antibodies.Type: GrantFiled: April 23, 2009Date of Patent: May 29, 2012Assignee: Millennium Pharmaceuticals, Inc.Inventor: Christopher C. Fraser
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NOVEL GENES ENCODING PROTEINS HAVING PROGNOSTIC, DIAGNOSTIC, PREVENTIVE, THERAPEUTIC, AND OTHER USES
Publication number: 20120045777Abstract: The invention provides isolated nucleic acids encoding a variety of proteins having diagnostic, preventive, therapeutic, and other uses. These nucleic and proteins are useful for diagnosis, prevention, and therapy of a number of human and other animal disorders. The invention also provides antisense nucleic acid molecules, expression vectors containing the nucleic acid molecules of the invention, host cells into which the expression vectors have been introduced, and non-human transgenic animals in which a nucleic acid molecule of the invention has been introduced or disrupted. The invention still further provides isolated polypeptides, fusion polypeptides, antigenic peptides and antibodies. Diagnostic, screening, and therapeutic methods using compositions of the invention are also provided. The nucleic acids and polypeptides of the present invention are useful as modulating agents in regulating a variety of cellular processes.Type: ApplicationFiled: June 27, 2011Publication date: February 23, 2012Applicant: Millennium Pharmaceuticals, Inc.Inventors: Christopher C. Fraser, Thomas M. Barnes, John D. Sharp, Susan J. Kirst, Paul S. Myers, Kevin R. Leiby, Douglas A. Holtzman, Sean A. McCarthy, Nicholas Wrighton, Charles R. Mackay, Andrew D.J. Goodearl -
Patent number: 8076086Abstract: The invention provides isolated nucleic acids encoding a variety of proteins and nucleic acids having diagnostic, preventive, therapeutic, and other uses. These nucleic acids and proteins are useful for diagnosis, prevention, and therapy of a number of human and other animal disorders. The invention also provides antisense nucleic acid molecules, expression vectors containing the nucleic acid molecules of the invention, host cells into which the expression vectors have been introduced, and non-human transgenic animals in which a nucleic acid molecule of the invention has been introduced or disrupted. The invention still further provides isolated polypeptides, fusion polypeptides, antigenic peptides and antibodies. Diagnostic, screening, and therapeutic methods utilizing compositions of the invention are also provided. The nucleic acids and polypeptides of the present invention are useful as modulating agents in regulating a variety of cellular processes.Type: GrantFiled: August 4, 2006Date of Patent: December 13, 2011Assignee: Millennium Pharmaceuticals, Inc.Inventors: Susan J. Kirst, Douglas A. Holtzman, Christopher C. Fraser, John D. Sharp, Thomas S. Barnes
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Publication number: 20110081656Abstract: The invention provides isolated nucleic acid molecules, designated TANGO 228 nucleic acid molecules, which encode secreted proteins with homology to the rat MCA-32 protein, isolated nucleic acid molecules, designated TANGO 240 nucleic acid molecules, which encode secreted proteins with homology to the Mycobacterium tuberculosis hypothetical protein Rv0712, and isolated nucleic acid molecules, designated TANGO 243 nucleic acid molecules, which encode proteins with homology to human PLAP (phospholipase A2-activating protein). The invention also provides antisense nucleic acid molecules, expression vectors containing the nucleic acid molecules of the invention, host cells into which the expression vectors have been introduced, and non-human transgenic animals in which a nucleic acid molecule of the invention has been introduced or disrupted. The invention still further provides isolated polypeptides, fusion polypeptides, antigenic peptides and antibodies.Type: ApplicationFiled: April 23, 2009Publication date: April 7, 2011Inventor: Christopher C. Fraser
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Novel genes encoding proteins having prognostic, diagnostic, preventive, therapeutic, and other uses
Publication number: 20110065124Abstract: The invention provides isolated TANGO 239, TANGO 219, TANGO 232, TANGO 281, A236 (INTERCEPT 236), TANGO 300, TANGO 353, TANGO 393, TANGO 402, TANGO 351 and TANGO 509 nucleic acid molecules and polypeptide molecules. The invention also provides antisense nucleic acid molecules, expression vectors containing the nucleic acid molecules of the invention, host cells into which the expression vectors have been introduced, and non-human transgenic animals in which a nucleic acid molecule of the invention has been introduced or disrupted. The invention still further provides isolated polypeptides, fusion polypeptides, antigenic peptides and antibodies. Diagnostic, screening and therapeutic methods utilizing compositions of the invention are also provided.Type: ApplicationFiled: May 20, 2010Publication date: March 17, 2011Inventors: Douglas A. Holtzman, John D. Sharp, Kevin R. Leiby, Steven Bossone, Yang Pan, Thomas M. Barnes, Christopher C. Fraser, Nicholas Wrighton, Paul S. Myers, Gillian Kingsbury -
Novel genes encoding proteins having prognostic, diagnostic, preventive, therapeutic, and other uses
Publication number: 20100291579Abstract: The invention provides isolated nucleic acid molecules and polypeptide molecules. The invention also provides antisense nucleic acid molecules, expression vectors containing the nucleic acid molecules of the invention, host cells into which the expression vectors have been introduced, and non-human transgenic animals in which a nucleic acid molecule of the invention has been introduced or disrupted. The invention still further provides isolated polypeptides, fusion polypeptides, antigenic peptides and antibodies. Diagnostic, screening and therapeutic methods utilizing compositions of the invention are also provided.Type: ApplicationFiled: July 1, 2010Publication date: November 18, 2010Inventors: Christopher C. Fraser, Sean Anthony McCarthy, John D. Sharp, Thomas M. Barnes, Nicholas C. Wrighton, Charles R. Mackay, Kevin R. Leiby, Douglas A. Holtzman -
Novel genes encoding proteins having prognostic, diagnostic, preventive, therapeutic, and other uses
Publication number: 20100062487Abstract: The invention provides isolated nucleic acids encoding a variety of proteins having diagnostic, preventive, therapeutic, and other uses. These nucleic and proteins are useful for diagnosis, prevention, and therapy of a number of human and other animal disorders. The invention also provides antisense nucleic acid molecules, expression vectors containing the nucleic acid molecules of the invention, host cells into which the expression vectors have been introduced, and non-human transgenic animals in which a nucleic acid molecule of the invention has been introduced or disrupted. The invention still further provides isolated polypeptides, fusion polypeptides, antigenic peptides and antibodies. Diagnostic, screening, and therapeutic methods using compositions of the invention are also provided. The nucleic acids and polypeptides of the present invention are useful as modulating agents in regulating a variety of cellular processes.Type: ApplicationFiled: May 8, 2009Publication date: March 11, 2010Inventors: Christopher C. Fraser, Thomas M. Barnes, John D. Sharp, Susan J. Kirst, Paul S. Myers, Kevin R. Leiby, Douglas A. Holtzman, Sean A. McCarthy, Nicholas Wrighton, Charles R. Mackay, Andrew D.J. Goodearl -
Publication number: 20090269783Abstract: Novel B7-like polypeptides, proteins, and nucleic acid molecules are disclosed. In addition to isolated, full-length B7-like proteins, the invention further provides isolated B7-like fusion proteins, antigenic peptides, and anti-B7-like antibodies. The invention also provides B7-like nucleic acid molecules, recombinant expression vectors containing a nucleic acid molecule of the invention, host cells into which the expression vectors have been introduced, and nonhuman transgenic animals in which a B7-like gene has been introduced or disrupted. Diagnostic, screening, and therapeutic methods utilizing compositions of the invention are also provided.Type: ApplicationFiled: August 20, 2008Publication date: October 29, 2009Inventors: Anthony J. Coyle, Christopher C. Fraser, Stephen Manning
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Novel genes encoding proteins having prognostic, diagnostic, preventive, therapeutic, and other uses
Publication number: 20090220977Abstract: The invention provides isolated nucleic acid molecules and polypeptide molecules. The invention also provides antisense nucleic acid molecules, expression vectors containing the nucleic acid molecules of the invention, host cells into which the expression vectors have been introduced, and non-human transgenic animals in which a nucleic acid molecule of the invention has been introduced or disrupted. The invention still further provides isolated polypeptides, fusion polypeptides, antigenic peptides and antibodies. Diagnostic, screening and therapeutic methods utilizing compositions of the invention are also provided.Type: ApplicationFiled: January 9, 2009Publication date: September 3, 2009Inventors: Christopher C. Fraser, Sean Anthony McCarthy, John D. Sharp, Thomas M. Barnes, Nicholas C. Wrighton, Charles R. Mackay, Kevin R. Leiby, Douglas A. Holtzman -
Patent number: 7544491Abstract: The invention provides isolated nucleic acid molecules, designated TANGO 228 nucleic acid molecules, which encode secreted proteins with homology to the rat MCA-32 protein, isolated nucleic acid molecules, designated TANGO 240 nucleic acid molecules, which encode secreted proteins with homology to the Mycobacterium tuberculosis hypothetical protein Rv0712, and isolated nucleic acid molecules, designated TANGO 243 nucleic acid molecules, which encode proteins with homology to human PLAP (phospholipase A2-activating protein). The invention also provides antisense nucleic acid molecules, expression vectors containing the nucleic acid molecules of the invention, host cells into which the expression vectors have been introduced, and non-human transgenic animals in which a nucleic acid molecule of the invention has been introduced or disrupted. The invention still further provides isolated polypeptides, fusion polypeptides, antigenic peptides and antibodies.Type: GrantFiled: September 7, 2007Date of Patent: June 9, 2009Assignee: Millennium Pharmaceuticals, Inc.Inventor: Christopher C. Fraser
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Publication number: 20090136959Abstract: The invention provides isolated nucleic acids encoding a variety of proteins having diagnostic, preventive, therapeutic, and other uses. These nucleic and proteins are useful for diagnosis, prevention, and therapy of a number of human and other animal disorders. The invention also provides antisense nucleic acid molecules, expression vectors containing the nucleic acid molecules of the invention, host cells into which the expression vectors have been introduced, and non-human transgenic animals in which a nucleic acid molecule of the invention has been introduced or disrupted. The invention still further provides isolated polypeptides, fusion polypeptides, antigenic peptides and antibodies. Diagnostic, screening, and therapeutic methods using compositions of the invention are also provided. The nucleic acids and polypeptides of the present invention are useful as modulating agents in regulating a variety of cellular processes.Type: ApplicationFiled: October 23, 2008Publication date: May 28, 2009Inventors: Sean A. McCarthy, Christopher C. Fraser, John D. Sharp, Thomas M. Barnes, Susan J. Kirst, Paul S. Myers, Nicholas Wrighton, Andrew D.J. Goodearl, Douglas A. Holtzman, Mehran Khodadoust