Patents by Inventor Christopher C. Lawrence

Christopher C. Lawrence has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Particles for immunoassays and methods for treating the same
    Patent number: 6890765
    Abstract: A method of treating particles to be used in immunoassays reduces interference in particle agglutination assays. For particles having covalently bound antibodies and residual NHS-ester or sNHS-ester groups on the surface, the reactive esters are treated with an aqueous mixture containing an amine compound of formula (I): H2N—R—X??(I). The moiety —X is —NH2, —OH, or —CO2CH2CH3; and R is an alkyl group or an alkyl ether group. When —X is —NH2 or —CO2CH2CH3, R contains from 1 to 20 carbon atoms; and when —X is —OH, R contains from 4 to 20 carbon atoms.
    Type: Grant
    Filed: December 18, 2001
    Date of Patent: May 10, 2005
    Assignee: Roche Diagnostics Operations, Inc.
    Inventors: Christopher C. Lawrence, Wei Yuan, Armen B. Shanafelt
  • Tertiary amine compounds for use in immunoassays
    Patent number: 6777246
    Abstract: A reagent for use in immunoassays reduces interference in particle agglutination assays. The reagent contains particles having covalently bound antibodies and a tertiary amine compound of formula (I): N(R1—X)(R2—Y)(R3—Z)  (I). The moieties R1, R2, and R3 are independently alkyl or alkyl ether. The moieties X, Y, and Z are independently —OH, —O—R4, —S—R4, —C(═O)—OH, —C(═O)—OR4, or —C(═O)—NHR4 (R4 is alkyl).
    Type: Grant
    Filed: December 18, 2001
    Date of Patent: August 17, 2004
    Assignee: Roche Diagnostics GmbH
    Inventors: Christopher C. Lawrence, Armen B. Shanafelt
  • Tertiary amine compounds for use in immunoassays
    Publication number: 20030138974
    Abstract: A reagent for use in immunoassays reduces interference in particle agglutination assays.
    Type: Application
    Filed: December 18, 2001
    Publication date: July 24, 2003
    Inventors: Christopher C. Lawrence, Armen B. Shanafelt
  • Particles for immunoassays and methods for treating the same
    Publication number: 20030092201
    Abstract: A method of treating particles to be used in immunoassays reduces interference in particle agglutination assays.
    Type: Application
    Filed: November 2, 2001
    Publication date: May 15, 2003
    Inventors: Christopher C. Lawrence, Wei Yuan, Armen B. Shanafelt
  • Particles for immunoassays and methods for treating the same
    Publication number: 20030087458
    Abstract: A method of treating particles to be used in immunoassays reduces interference in particle agglutination assays.
    Type: Application
    Filed: December 18, 2001
    Publication date: May 8, 2003
    Inventors: Christopher C. Lawrence, Wei Yuan, Armen B. Shanafelt