Patents by Inventor Christopher C. LINDSEY

Christopher C. LINDSEY has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • 5HT1F receptor agonists and mitochondrial biogenesis
    Patent number: 11939301
    Abstract: Provided herein are compounds of the formula (I): as well as pharmaceutically acceptable salts thereof, wherein the substituents are as those disclosed in the specification. These compounds, and the pharmaceutical compositions containing them, promote mitochondrial biogenesis and are useful for the treatment of, for example, acute kidney injury and chronic kidney disease.
    Type: Grant
    Filed: April 23, 2021
    Date of Patent: March 26, 2024
    Assignees: MUSC Foundation for Research Development, The United States Government as Represented by the Department of Veterans Affairs
    Inventors: Christopher C. Lindsey, Craig C. Beeson, Yuri Karl Peterson, Rick G. Schnellmann
  • 5HT1F RECEPTOR AGONISTS AND MITOCHONDRIAL BIOGENESIS
    Publication number: 20210238147
    Abstract: Provided herein are compounds of the formula (I): as well as pharmaceutically acceptable salts thereof, wherein the substituents are as those disclosed in the specification. These compounds, and the pharmaceutical compositions containing them, promote mitochondrial biogenesis and are useful for the treatment of, for example, acute kidney injury and chronic kidney disease.
    Type: Application
    Filed: April 23, 2021
    Publication date: August 5, 2021
    Inventors: Christopher C. LINDSEY, Craig C. BEESON, Yuri Karl PETERSON, Rick G. SCHNELLMANN
  • 5HT1F receptor agonists and mitochondrial biogenesis
    Patent number: 11014892
    Abstract: Provided herein are compounds of the formula (I): as well as pharmaceutically acceptable salts thereof, wherein the substituents are as those disclosed in the specification. These compounds, and the pharmaceutical compositions containing them, promote mitochondrial biogenesis and are useful for the treatment of, for example, acute kidney injury and chronic kidney disease.
    Type: Grant
    Filed: November 2, 2017
    Date of Patent: May 25, 2021
    Assignees: MUSC FOUNDATION FOR RESEARCH DEVELOPMENT, The United States Government as Represented by the DEPARTMENT OF VETERANS AFFAIRS
    Inventors: Christopher C. Lindsey, Craig C. Beeson, Yuri Karl Peterson, Rick G. Schnellmann
  • 5HT1F RECEPTOR AGONISTS AND MITOCHONDRIAL BIOGENESIS
    Publication number: 20200055827
    Abstract: Provided herein are compounds of the formula (I): as well as pharmaceutically acceptable salts thereof, wherein the substituents are as those disclosed in the specification. These compounds, and the pharmaceutical compositions containing them, promote mitochondrial biogenesis and are useful for the treatment of, for example, acute kidney injury and chronic kidney disease.
    Type: Application
    Filed: November 2, 2017
    Publication date: February 20, 2020
    Inventors: Christopher C. LINDSEY, Craig C. BEESON, Yuri Karl PETERSON, Rick G. SCHNELLMANN
  • Aza-ellipticine analogs, methods of synthesis and methods of treatment
    Patent number: 10456400
    Abstract: In some aspects, the present invention relates to aza-ellipticine compounds of the formula: wherein the variables are as defined herein. The application also provides novel methods of preparing aza-ellipticine compounds, methods of using the compounds, and pharmaceutical compositions thereof.
    Type: Grant
    Filed: May 15, 2015
    Date of Patent: October 29, 2019
    Assignee: MUSC Foundation for Research Development
    Inventors: Christopher C. Lindsey, Craig C. Beeson
  • Oxindole compounds and pharmaceutical compositions thereof
    Patent number: 10370328
    Abstract: Provided herein are compounds of the formula (I) as well as pharmaceutically acceptable salts thereof, wherein the substituents are as those disclosed in the specification. These compounds, and the pharmaceutical compositions containing them, are useful for the treatment of degenerative diseases and disorders.
    Type: Grant
    Filed: April 28, 2016
    Date of Patent: August 6, 2019
    Assignee: MUSC Foundation for Research Development
    Inventors: Craig C. Beeson, Christopher C. Lindsey, Baerbel Rohrer, Yuri Karl Peterson
  • Pyrazole compounds, compositions and methods for treatment of degenerative diseases and disorders
    Patent number: 9981994
    Abstract: Provided herein are compounds of the formula (I): as well as pharmaceutically acceptable salts thereof, wherein the substituents are as those disclosed in the specification. These compounds, and the pharmaceutical compositions containing them, are useful for the treatment of degenerative diseases and disorders.
    Type: Grant
    Filed: January 17, 2017
    Date of Patent: May 29, 2018
    Assignee: MUSC FOUNDATION FOR RESEARCH DEVELOPMENT
    Inventors: Craig C. Beeson, Christopher C. Lindsey, Yuri K. Peterson, Baerbel Rohrer
  • OXINDOLE COMPOUNDS AND PHARMACEUTICAL COMPOSITIONS THEREOF
    Publication number: 20180134659
    Abstract: Provided herein are compounds of the formula (I) as well as pharmaceutically acceptable salts thereof, wherein the substituents are as those disclosed in the specification. These compounds, and the pharmaceutical compositions containing them, are useful for the treatment of degenerative diseases and disorders.
    Type: Application
    Filed: April 28, 2016
    Publication date: May 17, 2018
    Inventors: Craig C. BEESON, Christopher C. LINDSEY, Baerbel ROHRER
  • Isatin compounds, compositions and methods for treatment of degenerative diseases and disorders
    Patent number: 9920029
    Abstract: Provided herein are compounds of the formula (I): as well as pharmaceutically acceptable salts thereof, wherein the substituents are as those disclosed in the specification. These compounds, and the pharmaceutical compositions containing them, are useful for the treatment of degenerative diseases and disorders.
    Type: Grant
    Filed: April 14, 2015
    Date of Patent: March 20, 2018
    Assignee: MUSC FOUNDATION FOR RESEARCH DEVELOPMENT
    Inventors: Craig C. Beeson, Christopher C. Lindsey, Yuri K. Peterson, Baerbel Rohrer
  • Thiazole compounds, compositions and methods for treatment of degenerative diseases and disorders
    Patent number: 9850218
    Abstract: Provided herein are compounds of the formula (I): as well as pharmaceutically acceptable salts thereof, wherein the substituents are as those disclosed in the specification. These compounds, and the pharmaceutical compositions containing them, are useful for the treatment of degenerative diseases and disorders.
    Type: Grant
    Filed: January 14, 2016
    Date of Patent: December 26, 2017
    Assignee: MUSC Foundation For Research Development
    Inventors: Craig C. Beeson, Christopher C. Lindsey, Yuri K. Peterson, Baerbel Rohrer
  • PYRAZOLE COMPOUNDS, COMPOSITIONS AND MEHTODS FOR TREATMENT OF DEGENERATIVE DISEASES AND DISORDERS
    Publication number: 20170121353
    Abstract: Provided herein are compounds of the formula (I): as well as pharmaceutically acceptable salts thereof, wherein the substituents are as those disclosed in the specification. These compounds, and the pharmaceutical compositions containing them, are useful for the treatment of degenerative diseases and disorders.
    Type: Application
    Filed: January 17, 2017
    Publication date: May 4, 2017
    Inventors: Craig C. Beeson, Christopher C. Lindsey, Yuri K. PETERSON, Baerbel Rohrer
  • AZA-ELLIPTICINE ANALOGS, METHODS OF SYNTHESIS AND METHODS OF TREATMENT
    Publication number: 20170081328
    Abstract: In some aspects, the present invention relates to aza-ellipticine compounds of the formula: wherein the variables are as defined herein. The application also provides novel methods of preparing aza-ellipticine compounds, methods of using the compounds, and pharmaceutical compositions thereof.
    Type: Application
    Filed: May 15, 2015
    Publication date: March 23, 2017
    Inventors: Christopher C. Lindsey, Craig C. Beeson
  • Pyrazole compounds, compositions and methods for treatment of degenerative diseases and disorders
    Patent number: 9556207
    Abstract: Provided herein are compounds of the formula (I): as well as pharmaceutically acceptable salts thereof, wherein the substituents are as those disclosed in the specification. These compounds, and the pharmaceutical compositions containing them, are useful for the treatment of degenerative diseases and disorders.
    Type: Grant
    Filed: October 29, 2014
    Date of Patent: January 31, 2017
    Assignee: MUSC FOUNDATION FOR RESEARCH DEVELOPMENT
    Inventors: Craig C. Beeson, Christopher C. Lindsey, Yuri K. Peterson, Baerbel Rohrer
  • THIAZOLE COMPOUNDS, COMPOSITIONS AND METHODS FOR TREATMENT OF DEGENERATIVE DISEASES AND DISORDERS
    Publication number: 20160130241
    Abstract: Provided herein are compounds of the formula (I): as well as pharmaceutically acceptable salts thereof, wherein the substituents are as those disclosed in the specification. These compounds, and the pharmaceutical compositions containing them, are useful for the treatment of degenerative diseases and disorders.
    Type: Application
    Filed: January 14, 2016
    Publication date: May 12, 2016
    Inventors: Craig C. BEESON, Christopher C. LINDSEY, Yuri K. PETERSON, Baerbel ROHRER
  • Isatin Compounds, Compositions And Methods For Treatment Of Degenerative Diseases And Disorders
    Publication number: 20150218128
    Abstract: Provided herein are compounds of the formula (I): as well as pharmaceutically acceptable salts thereof, wherein the substituents are as those disclosed in the specification. These compounds, and the pharmaceutical compositions containing them, are useful for the treatment of degenerative diseases and disorders.
    Type: Application
    Filed: April 14, 2015
    Publication date: August 6, 2015
    Inventors: Craig C. Beeson, Christopher C. Lindsey, Yuri K. Peterson, Baerbel Rohrer
  • Isatin compounds, compositions and methods for treatment of degenerative diseases and disorders
    Patent number: 9079853
    Abstract: Provided herein are compounds of the formula (I): as well as pharmaceutically acceptable salts thereof, wherein the substituents are as those disclosed in the specification. These compounds, and the pharmaceutical compositions containing them, are useful for the treatment of degenerative diseases and disorders.
    Type: Grant
    Filed: March 13, 2013
    Date of Patent: July 14, 2015
    Assignee: MUSC FOUNDATION FOR RESEARCH DEVELOPMENT
    Inventors: Craig C. Beeson, Christopher C. Lindsey, Yuri K. Peterson, Baerbel Rohrer
  • PYRAZOLE COMPOUNDS, COMPOSITIONS AND METHODS FOR TREATMENT OF DEGENERATIVE DISEASES AND DISORDERS
    Publication number: 20150057247
    Abstract: Provided herein are compounds of the formula (I): as well as pharmaceutically acceptable salts thereof, wherein the substituents are as those disclosed in the specification. These compounds, and the pharmaceutical compositions containing them, are useful for the treatment of degenerative diseases and disorders.
    Type: Application
    Filed: October 29, 2014
    Publication date: February 26, 2015
    Inventors: Craig C. Beeson, Christopher C. Lindsey, Yuri K. Peterson, Baerbel Rohrer
  • Pyrazole compounds, compositions and methods for treatment of degenerative diseases and disorders
    Patent number: 8921401
    Abstract: Provided herein are compounds of the formula (I): as well as pharmaceutically acceptable salts thereof, wherein the substituents are as those disclosed in the specification. These compounds, and the pharmaceutical compositions containing them, are useful for the treatment of degenerative diseases and disorders.
    Type: Grant
    Filed: March 13, 2013
    Date of Patent: December 30, 2014
    Assignee: MUSC Foundation for Research Development
    Inventors: Craig C. Beeson, Christopher C. Lindsey, Yuri K. Peterson, Baerbel Rohrer
  • PYRAZOLE COMPOUNDS, COMPOSITIONS AND METHODS FOR TREATMENT OF DEGENERATIVE DISEASES AND DISORDERS
    Publication number: 20140274950
    Abstract: Provided herein are compounds of the formula (I): as well as pharmaceutically acceptable salts thereof, wherein the substituents are as those disclosed in the specification. These compounds, and the pharmaceutical compositions containing them, are useful for the treatment of degenerative diseases and disorders.
    Type: Application
    Filed: March 13, 2013
    Publication date: September 18, 2014
    Applicant: Medical University of South Carolina
    Inventors: Craig C. BEESON, Christopher C. LINDSEY, Yuri K. PETERSON, Baerbel ROHRER
  • ISATIN COMPOUNDS, COMPOSITIONS AND METHODS FOR TREATMENT OF DEGENERATIVE DISEASES AND DISORDERS
    Publication number: 20140275075
    Abstract: Provided herein are compounds of the formula (I): as well as pharmaceutically acceptable salts thereof, wherein the substituents are as those disclosed in the specification. These compounds, and the pharmaceutical compositions containing them, are useful for the treatment of degenerative diseases and disorders.
    Type: Application
    Filed: March 13, 2013
    Publication date: September 18, 2014
    Applicant: MUSC FOUNDATION FOR RESEARCH DEVELOPMENT
    Inventors: Craig C. BEESON, Christopher C. LINDSEY, Yuri K. PETERSON, Baerbel ROHRER