Abstract: A hub assembly is provided. The hub assembly including a main body including a cavity, an aperture extending from an exterior surface of the main body to the cavity, and an attachment component disposed within the cavity. The attachment component includes a vent fluidly connected to the aperture, and a distal portion configured to fixedly attach a catheter lumen. The flow path is fluidly connected to the aperture and defined by an exterior surface of the attachment component and an interior surface of the cavity.

Abstract: A locking mechanism is provided including a proximal component including a distal end including a first spanning distance and a gap disposed between a material of the distal end defining the first spanning distance. A distal component is rotationally coupled with the proximal portion. The distal component includes a cavity including a distal end, the cavity rotationally coupled with the distal end of the proximal component. The cavity includes a second spanning distance of the distal end of the cavity. A rotation of the proximal component with respect to the distal component, or the distal component with respect to the proximal component, is configured to align a direction of the first spanning distance with a direction of the second spanning distance and diminish the gap of the proximal component.

Abstract: Devices used to restrict flow within a blood vessel are disclosed. Devices within the scope of this disclosure include a braided lattice of nitinol wires that form self-expanding enclosures of an embolic structure. The devices may further include embolic particles disposed within the enclosures. Methods of deploying the devices with the embolic particles are disclosed. Methods of manufacturing the devices with the embolic particles disposed within the enclosures are disclosed.

Abstract: Medical appliances may be formed of multilayered constructs. The layers of the constructs may be configured with various physical properties or characteristics. The disposition and arrangement of each layer may be configured to create an overall construct with a combination of the individual properties of the layers. Constructs may be used to create vascular prostheses or other medical devices.

Abstract: Endovascular prostheses used to treat diseased blood vessels, such as arteries, are disclosed. In some embodiments, the endovascular prosthesis is configured to be implanted within the diseased blood vessels adjacent a diseased section. The endovascular prosthesis may include a selectively openable internal duct configured to sealingly receive an expandable endovascular prosthesis that extends into a side branch vessel of the diseased blood vessel.

Abstract: Devices used to restrict flow within a blood vessel are disclosed. Devices within the scope of this disclosure include a braided lattice of nitinol wires that form self-expanding enclosures of an embolic structure. The devices may further include embolic particles disposed within the enclosures. Methods of deploying the devices with the embolic particles are disclosed. Methods of manufacturing the devices with the embolic particles disposed within the enclosures are disclosed.

Abstract: A vascular prosthesis deployment device and related methods are disclosed. In some embodiments the deployment device may include a delivery catheter assembly. The delivery catheter assembly may include a pliant member, wherein the pliant member is configured receive a vascular prosthesis. The pliant member may also be configured to aid in incrementally deploying a vascular prosthesis.

Abstract: Endovascular prostheses used to treat diseased blood vessels, such as arteries, are disclosed. In some embodiments, the endovascular prosthesis is configured to be implanted within the diseased blood vessels adjacent a diseased section. The endovascular prosthesis may include a selectively openable internal duct configured to sealingly receive an expandable endovascular prosthesis that extends into a side branch vessel of the diseased blood vessel.

Abstract: Devices used to pressurize, depressurize, or otherwise displace fluid are disclosed. The devices may be configured to displace fluid in order to inflate or deflate a medical device, such as a balloon. The devices include a trigger configured to convert the devices from a pressurization state to a priming state. The devices further include a locking or toggle member configured to toggle and/or maintain the devices in a priming state.

Abstract: Endovascular prostheses used to treat diseased blood vessels, such as arteries, are disclosed. In some embodiments, an endovascular prosthesis is configured to be implanted within a diseased blood vessel adjacent a diseased section. The endovascular prosthesis may include a fenestration tube through which a guidewire extends in a sealed configuration. The fenestration tube can be selectively openable and configured to sealingly receive an expandable endovascular prosthesis that extends into a side branch vessel of the diseased blood vessel.

Abstract: Endovascular prostheses used to treat diseased blood vessels, such as arteries, are disclosed. In some embodiments, an endovascular prosthesis is configured to be implanted within a diseased blood vessel adjacent a diseased section. The endovascular prosthesis may include a fenestration tube through which a guidewire extends in a sealed configuration. The fenestration tube can be selectively openable and configured to sealingly receive an expandable endovascular prosthesis that extends into a side branch vessel of the diseased blood vessel.

Abstract: Endovascular prostheses used to treat diseased blood vessels, such as arteries, are disclosed. In some embodiments, an endovascular prosthesis is configured to be implanted within a diseased blood vessel adjacent a diseased section. The endovascular prosthesis may include a fenestration tube through which a guidewire extends in a sealed configuration. The fenestration tube can be selectively openable and configured to sealingly receive an expandable endovascular prosthesis that extends into a side branch vessel of the diseased blood vessel.

Abstract: Endovascular prostheses used to treat diseased blood vessels, such as arteries, are disclosed. In some embodiments, an endovascular prosthesis is configured to be implanted within a diseased blood vessel adjacent a diseased section. The endovascular prosthesis may include a fenestration tube through which a guidewire extends in a sealed configuration. The fenestration tube can be selectively openable and configured to sealingly receive an expandable endovascular prosthesis that extends into a side branch vessel of the diseased blood vessel.

Abstract: A vascular prosthesis deployment device and related methods are disclosed. In some embodiments the deployment device may include a delivery catheter assembly. The delivery catheter assembly may include an outer sheath, an intermediate sheath, and an inner sheath. One or more of the outer sheath, the intermediate sheath, and the inner sheath may be reinforced with a braided structure to prevent elongation and ovalization of the sheaths. The braided structure may include one or more yarn members imbedded in a material and formed from a plurality of twisted singles. The twisted singles may be formed from an aromatic polyamide material.

Abstract: Vascular access assemblies for facilitating hemodialysis of a patient. The vascular access assembly may include a first tubular conduit and a bifurcated stent disposed in the superior vena cava. The vascular access assembly may further include a second tubular conduit that connects that couples an arm of the bifurcated stent to the first tubular conduit to create a blood flow pathway between two locations of a vasculature of a patient.

Abstract: Hybrid stent prosthesis and related methods for their use are described herein. A hybrid stent prosthesis may include a self-expanding stent frame, a balloon-expandable stent frame, and a cover integrating the self-expanding stent frame and the balloon-expandable stent frame. In some cases, the hybrid stent prosthesis may further include a transition zone and/or one or more markers. In some circumstances, the hybrid stent prosthesis may be advanced through the anatomy of a patient by a delivery catheter system and deployed at a deployment site by a deployment system of the delivery catheter system. A balloon inflation corresponding to the balloon-expandable stent frame may anchor the hybrid stent prosthesis. After anchoring, the self-expanding stent frame may be allowed to expand to its deployed configuration. The distal end of the balloon-expandable stent frame may then be further expanded to match anatomy. In cases, the hybrid stent prosthesis deploys with/in a parent prosthesis.

Abstract: Expandable branching stent prostheses and methods of deployment for the same are discussed herein. An expandable branching stent prosthesis may include a trunk portion, a first branching portion, and a second branching portion that are for deployment at, respectively, a trunk, a first branch, and a second branch of a branching implant site of an anatomical system. Methods for deploying the expandable branching stent prostheses include delivering a deployment system including the expandable branding stent prostheses, a balloon, a distal end of a floss wire, and in some cases a sock to the branching implant site; connecting, to the floss wire, a distal end of a snare wire delivered to the branching implant site via the second branch, and using the two floss wires to manipulate the deployment system to effectuate the deployment. In some cases, the sock may be pulled down over the balloon after the deployment.

Abstract: A vascular stent for treating a patient that can be manipulating remotely when the vascular stent is in a compressed configuration or in an expanded configuration. The vascular stent comprises a plurality of strings that can be used to open fenestrations on the vascular stent, manipulate the frame of the vascular stent, or shift the vascular stent within a vessel of a patient.

Abstract: A balloon expandable branching stent prosthesis are discussed herein. The balloon expandable branching stent prosthesis includes a trunk portion including a trunk portion stent frame, a first branching portion including a first branching portion stent frame, a second branching portion including a second branching portion stent frame, and a cover coupling the trunk portion stent frame, the first branching stent frame, and the second branching stent frame together forming a bifurcated stent, wherein the trunk portion stent frame, the first branching portion stent frame, and the second branching portion stent frame are spaced apart from each other with the cover disposed therebetween. A crotch portion of the balloon expandable branching stent prosthesis is disposed between the trunk portion, the first branching portion, and the second branching portion and the crotch portion is reinforced to prevent radial infolding of the cover.

Abstract: A stent for treating a patient that may comprise a body with a first end portion with a first opening and a second end portion with a second opening opposite the first opening. A stent may include a lumen that extends from the first opening to the second opening. The stent includes a single fenestration disposed in a sidewall of the body between the first opening and the second opening. The single fenestration is disposed in a center portion of the body of the stent in a length direction.